Alexis Lomakin, Ph.D. (אל) אַלעקסיס לאָמאַקין

The second part of my PhD thesis: The role of the microtubule cytoskeleton in the assembly & dynamics of cytoplasmic stress granules. This is how the AI powered artwork tool Wombo Art app.wombo.art sees it. I absolutely love the aesthetics of it! @stress_granules

Plasma Membrane Damage (0.005~0.09% SDS) induces Yeast or Fibroblast #Senescence Activating p53-p21 axis but independently of DNA damage response Roles of ESCRT (CHMP4B) & Glycoprotein VI Really interested if PMD-senescence occurs in endothelial/muscle cells, or by…

NEW content online! Replication timings affect the frequency of chromosomal translocation bit.ly/4mcaPfT

In a new Perspective article, Josh Morgan @WashU discusses how progress in cell biology is hindered by significance testing and the need for a shift to effect size estimation. hubs.la/Q03ytY7h0 #Technology #Reproducibility #CellCycle #CellDivision #Statistics

New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes? biorxiv.org/content/10.110…

Global inhibition of deadenylation stabilizes the transcriptome in mitotic cells biorxiv.org/content/10.110… #biorxiv_cellbio

Senescence: Returning aging cells to productivity elifesciences.org/articles/107777

Protein structure prediction contest CASP gets temporary funding from Google DeepMind as NIH grant runs out. trib.al/bGoz7lf

Boehringer Ingelheim Stiftung has committed €7 million to EMBL’s Imaging Centre. That means more opportunities to create groundbreaking, next-gen imaging technologies & provide necessary support to European life scientists. embl.org/news/connectio…

For years I have dreamt of a tool that could neutralize pathogens the moment they emerge. Today we unveil ApexOracle—an AI that, from a pathogen’s genome and phenotypic knowledge alone, predicts which antibiotics will work and invents new molecules for threats it has never seen.…

Check our new article in B cell mechanoresponses 💥 @Peaceiton @IsidoraRiobo @coffee_lipe @Jheim01309974 @Cabrera_R_FE @ContrerasTeemly @sarahdezperez @mattilalab

Construction and phenotypic classification of synthetic dual-pole Escherichia coli cells "a genetic circuit that enables two distinct scaffolding proteins to localize at opposite poles in E. coli" nature.com/articles/s4200…

Biomolecular condensates at the nuclear pore basket maintain global chromatin organization biorxiv.org/content/10.110… #biorxiv_cellbio

Does viscoelastic confinement physically alter cell proliferation? Sree @padmanabh97 & @Mridul_Gautam01, along with @bagade_nikita18 & Sunil Laxman, discovered a 3D confinement-driven cell cycle regulation in budding yeast. (1/9) @NCBS_Bangalore @ESoftbio tinyurl.com/esoftbio20252

Tiny molecular spirals in cells can scale up to control the twist and turn of entire tissues – an important step towards understanding left-right symmetry in tissues and organs. elifesciences.org/articles/10229…

m6A-induced ribosome stalling and collision trigger mRNA decay dlvr.it/TM2C4P

Today is #NationalIceCreamDay Natural antifreeze proteins purified have been used as a preservative in ice cream

Eukaryotic ribosome biogenesis youtube.com/watch?v=ETkwf6…

Cells are so tiny that measuring their weight seems, at first blush, like an impossible task. But back in 1953, two biologists from Southern Illinois University — supported, in part, with funding from Anheuser-Busch! — invented a super clever method for figuring out the weight…

Take a brief survey at the RCSB PDB booth at #aca2025 and you'll be entered in a survey to win a mini-print from David Goodsell

1/ No, you do not always need single-cell RNA-seq. Here's why bulk RNA-seq might still be the smarter move for your experiment.