Journal of Cell Biology

New Perspective: Brian North, Christopher Shoemaker @shoemaker_lab et al. @GeiselMed highlight emerging evidence that LIRs act as protein interaction hotspots, coordinating diverse protein–protein interactions across the #autophagy pathway. hubs.la/Q03yMFKv0

.@srishti_mandal and @Sudha__Kumari @iiscbangalore highlight new work from @LabYuseff (hubs.ly/Q03yztgP0), describing mechanisms underlying the effect of #mechanotransduction in B cells on antigen extraction & presentation at the immune synapse hubs.ly/Q03yzvJs0

In a new Perspective article, Josh Morgan @WashU discusses how progress in cell biology is hindered by significance testing and the need for a shift to effect size estimation. hubs.la/Q03ytY7h0 #Technology #Reproducibility #CellCycle #CellDivision #Statistics

Abraham Martinez, Chad Pearson et al. @CUAnschutz reveal that the RNA-binding protein, UNK, facilitates PLK4-induced #centriole overduplication and promotes centriole and centriolar satellite protein localization. hubs.la/Q03ytVYV0 #RNAbiology #Cancer #Centrosomes

📢 For all HaloTag lovers💙💚💛❤️💜🩶 we are excited to share that our work, in which we developed a new biotin-HaloTag ligand, is now published in @JCellBiol! Full link here: rupress.org/jcb/article-ab…

Dennison and Baldridge @UMichMedScience reveal how the #Golgi-localized Tul1 #ubiquitin ligase complex targets substrates to the #proteasome versus the vacuole in S. cerevisiae. hubs.la/Q03yh31t0 #Biochemistry #ProteinHomeostasis

Check our new article in B cell mechanoresponses 💥 @Peaceiton @IsidoraRiobo @coffee_lipe @Jheim01309974 @Cabrera_R_FE @ContrerasTeemly @sarahdezperez @mattilalab

We have written a spotlight on this fantastic paper as well @mattilalab @labyuseff @srishti_mandal check it out: rupress.org/jcb/article/22…

Finally! My PhD work is out in @JCellBiol 😀 Thanks to everyone involved at @LabYuseff, @sarahdezperez and @mattilalab . It took a while but was completely worth it 🙌

🧬 My first paper is out in Journal of Cell Biology! @JCellBiol We show how B cells use ATAT1 to sense stiffness, acetylate microtubules, and improve antigen presentation. Proud to share this milestone 🌎💪 🔗 rupress.org/jcb/article/22… #Bcells #Mechanobiology #Immunology #PhD

.@LabYuseff @uc_chile show that B cells respond to mechanical cues at the immune synapse through ATAT1-dependent microtubule acetylation to coordinate cytoskeletal dynamics & lysosome positioning, enhancing antigen extraction and presentation hubs.la/Q03y2G-f0

Borisyuk, Kaganovich, Amen et al. (@EPFL_en @unisouthampton) show that PKC promotes peroxisome-ER interactions and #peroxisome formation. hubs.la/Q03y2Cm30 ▶️ See video summary of the study by Howman: hubs.la/Q03y2Gk20 #ER_literature

Missed the @KeystoneSymp "#Autophagosomes and #Endolysosomes: Mechanisms to Disease Implications" in June? Register now for #OnDemand Access to explore emerging research! hubs.la/Q03x8W7k0 #KSAutophagy25

Our Phagoptosis paper is in Spotlight. @PrasadLabIISERK @NandiAbhrajyoti @devyan304 @SOUVIKDE244421

Powell and Ables @EastCarolina discuss work from Ghosh et al. (hubs.la/Q03xH2QH0), which reveals that ecdysone signaling reprograms epithelial follicle cells toward a phagocytic fate during #Drosophila late #oogenesis. hubs.la/Q03xH4Xb0

In new study from Muziyue Wu et al. @OWeinerLab, in vivo biochemistry sheds new light on how the WAVE complex templates the characteristic shape of lamellipodial protrusions. hubs.la/Q03xvbW90 #Cytoskeleton #Actin #Migration #Motility #Biophysics

.@yadav_anoop101, Jadhav, @SvendaJakub, @HanaSedlackova1 et al. present a novel cell-permeable biotin-HaloTag ligand. The reported ligand enables in vivo labeling & provides capabilities for efficient affinity capture of protein variants from live cells. hubs.la/Q03xv9Sd0

Paumier, Sauvanet, and Gigant highlight work from Muñoz-Hernández, Xu, @MikeVVieczorek et al. (hubs.la/Q03xjk310), which describes new insight into the means by which NEDD1 protein recruits the γ-TuRC to microtubule-organizing centers. hubs.la/Q03xj7000

Naughton et al @schliekerlab @YaleCellBio conducted force measurements within the endoplasmic reticulum (ER) measuring forces in the piconewton range uncovering a critical role for NOMO as force-bearing transmembrane protein that is critical for myogenesis hubs.la/Q03xj6rv0

Missed the @KeystoneSymp "#Neurodegeneration: Linking #CellularPathways to Therapeutic Strategies" in June? Register now for #OnDemand Access to explore emerging research! hubs.la/Q03x8Vj90 #KSNeuroDegen25