Aging Science News
@AgingBiology
Latest news in the biology and genetics of aging, covering longevity science, rejuvenation technologies and life-extension research. Tweets by @jpsenescence
New description of the Human Ageing Genomic Resources (HAGR) Since its inception 20 years ago, HAGR has become the leading online platform in ageing research. A brief thread on HAGR's databases 🧵 academic.oup.com/nar/article/52…
Analyses of the mechanism and therapeutic targets of senescence related genes in ischemic stroke with multi-omics approach nature.com/articles/s4159…
The emerging role of multiomics in aging research tandfonline.com/doi/abs/10.108…
Profiling Epigenetic Aging at Cell-Type Resolution Through Long-Read Sequencing onlinelibrary.wiley.com/doi/full/10.11…
Single-cell and spatial transcriptomics map senescent vascular cells in arterial remodeling during atherosclerosis in mice nature.com/articles/s4358…
Identification of Functional Cellular Markers Related to Human Health, Frailty and Chronological Age onlinelibrary.wiley.com/doi/full/10.11…
Even at 100+: Acute Exercise Modulates Inflammatory Pathways in Centenarians onlinelibrary.wiley.com/doi/full/10.11…
Senescence: Returning aging cells to productivity elifesciences.org/articles/107777
Rapamycin for longevity: the pros, the cons, and future perspectives frontiersin.org/journals/aging…
GrimAge and GrimAge2 Age Acceleration effectively predict mortality risk: a retrospective cohort study tandfonline.com/doi/full/10.10…
Proteins with cognition-associated structural changes in a rat model of aging exhibit reduced refolding capacity science.org/doi/10.1126/sc…
MethAgingDB: a comprehensive DNA methylation database for aging biology nature.com/articles/s4159…
Bryan Johnson Is Going to Die wired.com/story/big-inte…
A Machine-Learning Approach Identifies Rejuvenating Interventions in the Human Brain advanced.onlinelibrary.wiley.com/doi/10.1002/ad…
Proteomic aging signatures across mouse organs and life stages embopress.org/doi/full/10.10…
Multiorgan transcriptomics in mice identifies immunoglobulin heavy constant mu (Ighm) as a tissue-level aging biomarker pnas.org/doi/abs/10.107…
An unbiased comparison of 14 epigenetic clocks in relation to 10-year onset of 174 disease outcomes in 18,859 individuals medrxiv.org/content/10.110…
A multi-omics analysis of human fibroblasts overexpressing an Alu transposon reveals widespread disruptions in aging-associated pathways biorxiv.org/content/10.110…
Reactivation of retrotransposable elements is associated with environmental stress and ageing nature.com/articles/s4157…
CHIP and aging: a key regulator of proteostasis and cellular senescence link.springer.com/article/10.100…
