Chuanyun Xu
@Raiseemhigh
Postdoc-Baker lab @UW; PhD-Luo lab @Stanford
How I Met Your Mother/Father: The Synaptic Partner Matching Tale Thanks to incredible colleagues @LuoLabStanford and collaborators @JiefuBiol @aliceyting @BroadProteomics ! cell.com/cell/fulltext/…
1/14 On behalf of the amazing team in @JswLab, we’re excited to share PEtracer (biorxiv.org/content/10.110…) a prime editing-based evolving lineage recorder compatible with both scRNA-seq and high-resolution imaging readouts in intact tissue. By applying PEtracer in a syngeneic mouse…
Design of high specificity binders for peptide-MHC-I complexes 🚀 New preprint from David Baker!🚀 • Researchers from @UWproteindesign introduced a novel approach using deep learning tools like RFdiffusion to design specific protein binders for peptide-MHC-I (pMHC) complexes,…
lol
This year’s second place Graduate Sammy Kuo Award goes to Chuanyun Xu from Liqun Luo lab for his @CellCellPress paper on "Molecular and cellular mechanisms of teneurin signaling in synaptic partner matching."
Thrilled to share our latest work on lipid nanoparticle (LNP) delivery of a stable CRISPR-Cas9 ribonucleoprotein (RNP) for in vivo genome editing, now published @NatureBiotech! 🧬 nature.com/articles/s4158… In this paper, we first engineered robust, efficient, and stable…
Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR–Cas9 ribonucleoprotein go.nature.com/408uNAq
In the latest issue! Molecular and cellular mechanisms of teneurin signaling in synaptic partner matching dlvr.it/TCvXBT
What a wonderful journey this has been! Thanks to extraordinary colleagues!!!
Super excited to share our latest study led by the awesome @Raiseemhigh! Spatially-resolved proteomics + in vivo genetic and cell biology analyses united the molecular and cellular mechanisms of Teneurin in synaptic partner matching. biorxiv.org/content/10.110…
My second project @doudna_lab also has a topic on RNP delivery for genome editing in vivo. Different from using LNPs to package and transport gene editors, we engineered self-deliverable Cas9 RNPs through fusion to cell-penetrating peptides (CPPs). biorxiv.org/content/10.110…
Today I want to share two stories of my postdoc research @doudna_lab. The first project in collaboration with the Murthy lab at Berkeley describes our work on “lung and liver editing using lipid nanoparticle delivery of a stable CRISPR-Cas9 RNP”. biorxiv.org/content/10.110…
So excited to finally share one of the most fun and exciting projects from my PhD! Here, @beccajcarlson and I show that STING, a key player in the immune system, is a proton channel. Paper: lnkd.in/eQ6TXhvr MIT News Story: lnkd.in/eXExmjta
I was taken by surprise this morning when congratulatory emails started arriving in my inbox. I'm incredibly honored, grateful, and humbled to be included among such an esteemed group of scientists, many of whom I’ve admired for decades. While this recognition is individual,…
Super excited to share our latest study led by the awesome @Raiseemhigh! Spatially-resolved proteomics + in vivo genetic and cell biology analyses united the molecular and cellular mechanisms of Teneurin in synaptic partner matching. biorxiv.org/content/10.110…
And thank you, @GrinsteinJ for the nice interview with Eerik and Josh: Programmable RNA Sensors Enable Cell Editing and Therapeutic Intervention genengnews.com/gen-edge/progr… via @GENbio
BREAKING: Guanyu Zhou will race for Alfa Romeo in 2022, becoming China's first full-time #F1 driver
Fly Cell Atlas is out!! check BioRxiv and flycellatlas.org; thanks everyone #FCAconsortium. biorxiv.org/content/10.110…
New issue cell.com/neuron/current With a Joshua tree on the cover for @TakeoYukari, Shuster & coll. reporting that GluD2, a synapse organizer, supports Purkinje cell dendritic branching patterns & shape Paper bit.ly/3k1GK3Y Preview by Lu & Craig bit.ly/2Ztsd7D
