Hongjie Li
@HongjieLi5
Assistant professor & CPRIT scholar; aging and longevity research @ Baylor College of Medicine
Our Aging Fly Cell Atlas is out. Do different cell types age at the same rate? No. Which cell types age faster? Fat, liver and muscle. Which cell types age slower? Neurons. Great collaboration with @StephenQuake @HenriJasper @mariabrbic @TzuChiaoLu
🔥 Super cool research in longevity by Shift Bioscience! A new preprint ("A single factor for safer cellular rejuvenation") from Shift Bioscience reports a striking finding: a single gene, SB000, achieves robust cellular rejuvenation across two germ layers—fibroblasts and…
The dream of waking up in the near future and being substantially younger at a cellular level is something I have the rare privilege to pursue each day. However, keeping this dream alive is contingent on the following (1) making timely and meaningful technical progress towards…
My great honor to receive this prestigious DeBakey Award.
DeBakey Research Award recipient, Dr. Dr. @HongjieLi5, receives his award for his work on the #FlyCellAtlas. @bcmhouston @bcmgenetics
Can we build multimodal models by simply aligning pretrained unimodal models with limited paired data? We introduce STRUCTURE 🏗️: a lightweight, plug-and-play regularizer that preserves latent geometry to align frozen unimodal models using <1% of paired data typically used in…
#AlzheimersDisease Affects Tissues Beyond the #Brain. @HongjieLi5 Belen lab @YeJin_YeahGene @TzuChiaoLu explain their findings in @TheScientistLLC. @NeuroCellPress @bcmhouston @bcmgenetics @BCMGradSchool @TCHResearchNews the-scientist.com/alzheimer-s-di… @TheScientistLLC
❗Fresh OA 🔓 Publication Olfactory dysfunction increases progression to dementia in cognitively impaired older adults: a 12-year population-based study by Javier Oltra (@JotaOltra) & Erika J. Laukka et al. rdcu.be/ergXH #dementia #olfaction #populationbasedstudy…
News: NIH researchers conclude that taurine is unlikely to be a good aging biomarker bit.ly/4dPlcDe
#Alzheimers not only affects the brain, but many other organs as well. #fruitflyModel #Brain @HongjieLi5 Belen lab @YeJin_YeahGene @TzuChiaoLu explain their findings. @NeuroCellPress @bcmhouston @bcmgenetics @BCMGradSchool @TCHResearchNews blogs.bcm.edu/2025/06/03/fro…
We need to save the Flybase; without it I cannot be a scientist as today.
Read more about the study in @AgingCell that shows therapeutic plasma exchange combined with intravenous immunoglobulin reduced biological age on average by 2.6 years. Great to team up with @CirculateHealth on this. @furmanbios buckinstitute.org/news/clinical-…
virtual seminar events.cancer.gov/dcb/beyond-mam… #drosophila #CancerResearch
🗞️Our May issue is live!📷 This month, we're featuring work on planarians and rejuvenation, how ancient viruses factor into mammalian reproduction, mitochondrial biology in aging, age-related hearing loss, and much more. Read it all here 👇nature.com/nataging/volum…
Working w/ laboratory fruit fly, researchers Ye-Jin Park, Hugo Bellen, @HongjieLi5, et al. provide new understanding of how #AlzheimersDisease affects different tissues across entire body. @NeuroCellPress cell.com/neuron/abstrac… Overview @NeuroscienceNew neurosciencenews.com/alzheimers-who…
Our new study, published on Neuron, shows how Alzheimer’s disease impact the whole body at the single cell level. Led by @YeJin_YeahGene and @TzuChiaoLu. cell.com/neuron/abstrac…
#Alzheimers disease not only affects the #brain. @HongjieLi5 Belen lab @YeJin_YeahGene @TzuChiaoLu et al show it also impacts the whole body. @NeuroCellPress @bcmhouston @bcmgenetics @BCMGradSchool @TCHResearchNews bcm.edu/news/study-rev…
Read about Study reveals impacts of Alzheimer’s disease on the whole body here: bcm.edu/news/study-rev…
Want to discover, design, and engineer cutting-edge drug delivery vectors? We're hiring a PhD-level Scientist at the Horns Lab at @arcinstitute and @Stanford! Check out bit.ly/ScientistDeliv…
You don't intimidate me, you're going to be my best friend whether you like it or not!
Hepatic gluconeogenesis and PDK3 upregulation drive cancer cachexia in flies and mice. Liu, Dantas, Ferrer, Miao, Qadiri, Liu, Comjean , Davidson, Perrier, Ahmed, Hu, Goncalves, Janowitz, Perrimon. Nat Metab. 2025 doi: 10.1038/s42255-025-01265-2. PMID: 40275022