Xu Zhou (周旭)
@XuZhouLab
AP @BostonChildrens @harvardmed AM @broadinstitute inflammation, tissue biology, quant.&systems immunology #1stGen #ImmigrantScientists @xuzhoulab.bsky.social
Beyond excited to share our #NewPaper in @CellCellPress! Inflamed environments acidify intracellular pH. BRD4 senses this via transcriptional condensates, tuning #macrophage responses to match demand and consequences of inflammation. #inflammation #pH authors.elsevier.com/sd/article/S00…
Now online! Regulation of inflammatory responses by pH-dependent transcriptional condensates dlvr.it/TM0Mvr
Thanks for highlighting the preprint of our work, now online @CellCellPress authors.elsevier.com/sd/article/S00…
BRD4 acts as a pH sensor to tune inflammation bit.ly/3IOIyNU
🔥🔥🔥Endogenous oxidized lipids regulate polycomb complex to epigenetically control IL10 level! Congrats to @Lo_Zanzi and Marco! What an amazing discovery👏 honored to play a tiny part in this story 👇authors.elsevier.com/c/1lS0g3qNrU-i…
#EpigeneticPower! Our #NewPaper @ImmunityCP shows that endogenous oxidized lipids decide whether host survives or dies during #sepsis, #ARDS, or Staph infection! Ox lipids bind & inhibit #AKT, boosting inhibitory H3K27 methylation via EZH2, blocking #IL10! authors.elsevier.com/a/1lS0g3qNrU-i…
My lab is recruiting! We study respiratory immunology, chronic lung diseases and aging. Come join us @UVAimmunology at the beautiful UVA campus and Charlottesville. Please help spread the words.
Have been wating for this one: Macrophage derived growth factor promotes epithelial proliferation in the lung and tissue repair under inflammatory damage 🔥🔥🔥 huge congratulation to @RuthFranklinLab @RMedzhitov and the team! 🎉👏🏼🍾science.org/doi/10.1126/sc…
Key numbers in cell biology Having a sense of scale helps to think more rigorously and realistically about biological systems.
We are hiring! Please help spread the words. Thank you! nature.com/naturecareers/…
As I step down as @iuis president, I reflect on the achievements of immunology science & challenges ahead, and call on scientists to reclaim the narrative on science and explain with "humility &clarity" science’s contribution to global health & prosperity👉loom.ly/iZseYbQ
I don't think we're talking enough about how this Big Dumb Ugly Bill expands ICE by a factor of 20. ($2.2B to $45B) That's 20 times more agents. 20 times more arrests, plus illegal detention centers. Trump is using the bill to create his own paramilitary gestapo.
A list of 17 total universities around the USA announcing layoffs or cuts from this week alone…
17. University of Washington warns of potential layoffs kuow.org/stories/uw-pre…
2025 Nature Index: Harvard has dropped to No. 2 after the Chinese Academy of Sciences. No. 1 and 3-9 are all Chinese research institutes. Meanwhile, American research institutes are facing a 43% cut in NIH funding and a 50% cut in NSF funding. Please, don’t look up.
In the nucleus, many intrinsically disordered proteins (IDPs) form condensates. What IDP sequence features drive this behavior? We developed CondenSeq, a high-throughput method to measure nuclear condensate formation & applied it to ~14000 IDPs to find out rdcu.be/eq975