Nan Zhang
@NanZhangWistar
Aiming to cure #OvarianCancer #PeritonealMetastasis by manipulating #Macrophage #MyeloidCell #Microenvironment. Also on 🦋
Congratulations, Hong and the team!!!
Now online in @CD_AACR: An Immunomechanical Checkpoint PYK2 Governs Monocyte-to-Macrophage Differentiation in Pancreatic Cancer - by Wenyan Xie, Xin Yu, Qingxin Yang, Nengwen Ke, Ping Wang, Yun-Hua Liu, Bi-Sen Ding, Qiang Wei, Hong Jiang, and colleagues doi.org/10.1158/2159-8…
CSF1R regulates monocyte subset differentiation and intracellular metabolism. biorxiv.org/content/10.110… Our new preprint is now online ! Here, we explore links between CSF1R signalling, intracellular metabolism and monocyte differentiation.@LP2M_Lab @Cnrs20 @Univ_CotedAzur @Inserm
"writing is not only about reporting results; it also provides a tool to uncover new thoughts and ideas. Writing compels us to think"
Proud to share @niseto’s (new PI @TheCrick) paper: As a postdoc (@CSHL/@HopkinsMedicine), he found #NETs in necrotic tumors—I shrugged. But he looked closer: NETs block tumor vessel perfusion, causing necrosis, hypoxia, EMT & #Metastasis. nature.com/articles/s4158… @JHU_BDP @Nature
Have been wating for this one: Macrophage derived growth factor promotes epithelial proliferation in the lung and tissue repair under inflammatory damage 🔥🔥🔥 huge congratulation to @RuthFranklinLab @RMedzhitov and the team! 🎉👏🏼🍾science.org/doi/10.1126/sc…
We are hiring! Please help spread the words. Thank you! nature.com/naturecareers/…
Apply if you are interested in IBD, lymphatics, and mucosal immunology.
Share the news! We're excited to find a passionate postdoctoral researcher to help us take our incredible in vivo tools even further, with the hope of making a positive difference in the lives of IBD patients. Join our team @ImmunologyAU More info: shorturl.at/aTswK
Activation of macrophages engulfing neutrophils by TNF switches efferocytosis to caspase-8–mediated pyroptosis and IL-1β production @SciImmunology @LabPoltorak science.org/doi/10.1126/sc…
The last week has seen a convergence of studies looking at how to use IL-12 and approaches to overcome toxicity. Just a brief recap for @CytokineSociety @NatRevImmunol Single doses of the mRNA encoding IL-12 enhances mRNA vaccine induced CD8 T cells science.org/doi/10.1126/sc…
Hear from OCRP leaders in this video series on how the Ovarian Cancer Academy supports researchers in making ovarian cancer the focus of their scientific careers and accelerating progress in the field: youtube.com/watch?v=rC2GhP… youtube.com/watch?v=ogO4fq… youtube.com/watch?v=DwWVcP…
For the immunologists still on X science.org/doi/10.1126/sc…
Interferon-γ orchestrates leptomeningeal anti-tumour response @Nature nature.com/articles/s4158…
It was an awesome time! Meeting new people, learning new science, and setting up new collaborations! Thank you, @TheVFoundation!
Taking pictures like we were at a concert. Can you tell we had a great time at the V Foundation for Cancer Research Summit?
in ~15 years, metastatic melanoma went from a disease with a median 6 month survival time to one where 52% of patients have melanoma-specific survival 10 years out may we all get a chance to work on medical technologies like this - my god! nejm.org/doi/full/10.10…
“You are the best of the best.” We’re excited to be kicking off our annual V Foundation Cancer Research Summit today! It’s going to be a wonderful few days supporting our grantees. 🔬❤️
Our first in-person NIH Ovarian Cancer SPORE team meeting after the successful renewal! Great to see our Hopkins partners. Thank you to our EAB/IAB members for their time and insights. @JHUPath @HopkinsMedicine @PennCancer @RogerRogergr @BuckanovichLab @Penn_OCRC @NanZhangWistar
@kodiravi @SciImmunology Apoptotic cells are not all created equal science.org/doi/10.1126/sc…
Congratulations to @EJohnWherry and Penn colleagues, @kkariko (@PennNSG), Virginia Lee (@PennPathLabMed), and Mark Devlin (@physatpenn), on being elected as members of @theNASciences—one of the highest honors a scientist can receive!
Congratulations to @kkariko (@PennNSG), Virginia Lee (@PennPathLabMed), @EJohnWherry (@PennSysPharmATT) & Mark Devlin (@physatpenn) on their election to @theNASciences! tinyurl.com/5eehdtms
Yes! This is another @CD_AACR seminal study by the amazing @MaraShermanLab @MSKCancerCenter and her terrific team & colleagues. Check out this commentary about it by yours truly aacrjournals.org/cancerdiscover…
The final #OpenAccess version of @MaraShermanLab recent paper is now available on @CD_AACR Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor Progression aacrjournals.org/cancerdiscover…