Siyuan (Steven) Wang
@SStevenWang
Image-based spatial multi-omics. Associate Professor at Yale. NIH Director's New Innovator Awardee. MIT Technology Review 35 Innovators Under 35.
Deeply honored and humbled to have been selected to receive the ASCB Innovation In Research Award this year. I could not have received it without the immense support from my mentors and colleagues in the field, and the great work of my lab members. 1/2 ascb.org/society-news/a…

“Dr. Wu’s story shows us how the effect of unjust scrutiny and investigations of Chinese American scholars does not just end careers, it can end lives. Universities must be places of community, support, and fairness, not fear and coercion.” -@gkusawaka
“As painful as it is for us as her family to recount how Northwestern treated her, we are seeking justice to prevent this from happening again to others in the future,” Rao says.
Time for some justice and accountability.
@nbcnews has published a powerful feature on the death of pioneering Chinese American neuroscientist Dr. Jane Wu, who died by suicide on July 10, 2024, after Northwestern University abruptly shut down her laboratory: nbcnews.com/news/asian-ame…
I saw it firsthand at the #Lindau2025 Nobel Laureates meeting--international young scientists welcomed and recruited in Germany and elsewhere. Some of the very best are leaving, and many of the best will no longer come. wsj.com/politics/polic…
🧬 Congratulations to Dr. Stefania Nicoli @NicoliLab, newly elected Fellow of the American Heart Association (@American_Heart)! Her groundbreaking work on RNA biology is advancing cardiovascular research at @YaleMed. Read more: medicine.yale.edu/genetics/news-…
DNA methylation goes spatial! Introducing Spatial-DMT: a technology that co-profiles DNA methylation and transcriptome in the same tissue section. A fantastic collaboration with @zhouwanding lab. Kudos to Chin Nien Lee @ChinNLee2021 and Hongxiang Fu! biorxiv.org/content/10.110…
This is just awfuI…I hope the courts hasten the restoration of Uri’s R01! While NIH/HHS leaders sit there and say all is well…scientists’ lives are being destroyed for arbitrary reasons.
My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15
Our scMicro-C paper is out in @NatureGenet! Huge thanks to the reviewers for their valuable insights, to @XieSunney for unwavering support, and to fantastic collaborators @JiankunZhang21 & @tanlongzhi. Thrilled to share this work!
Very excited to share our work on high-resolution single-cell Micro-C, which is on bioRxiv now. Here we reveal that cohesin-mediated loop extrusion participates in transcription with kilobase-resolution single-cell 3D structures. biorxiv.org/content/10.110…
For those wondering about the NIH/NSF budgets...that is still a fight in congress, so contact your Reps!
The "Big Beautiful Bill" isn’t the federal budget—it’s a reconciliation bill focused on tax cuts. The real FY26 funding decisions for NIH, NSF, and more are happening now in Congress. ascb.org/science-policy…
Introducing Epi-PHR, the first non-disruptive, high-genomic-resolution, image-based epigenetic profiling method. Allelic Epi-PHR generates the first single-cell phased examination of histone mark deposition and 3D genome architecture at an imprinted locus by any technique. 1/8
high-throughput single-molecule platform to study DNA supercoiling effect on protein–DNA interactions academic.oup.com/nar/article/53…