Bhattacharyya Lab
@moitrayee_lab
science enthusiasts in Pharmacology @Yale studying molecular mechanisms of cell signaling in cancer and neurodegeneration (https://www.bhattacharyya-lab.org/)
Here is a tweetorial summarizing findings from our recent paper from @YalePharm @YaleMed in @NatureNano by @GTWalker7 and @CBcellbiologist. Dream team @shalgene @Xiangyu_GigiG @MuzumdarLab @GuptaLab1! Also see the N&Vs at nature.com/articles/s4156… by @KrishnanYamuna!
New content online: Oligomeric organization of membrane proteins from native membranes at nanoscale spatial and single-molecule resolution dlvr.it/SzNQf8
As we know, the human plasma🩸 proteome is crucial! The @labs_mann just published a fantastic study in @NatureGenet! And here is our News & Views highlighting the mapping of plasma protein QTLs and why #MassSpec remains a key player: nature.com/articles/s4158…. @asmsnews @hupo_org
Thrilled to share our latest work published in @NatureGenet today: Plasma proteome variation and its genetic determinants in children and adolescents. 🩸#PediatricProteomics #PlasmaProteomics #pQTL nature.com/articles/s4158… 🧵A thread by @hustniu explains below ⬇️
Many congratulations @JunLiuLab for this beautiful work!
Exciting findings from @JunLiuLab #postdoc @YueJianUSTC @YaleMed Architecture and activation of the Legionella Dot/Icm type IVB secretion machine #cryoEM #cryoET #Legionella biorxiv.org/content/10.110…
The call just opened! ki.se/en/about-ki/jo… You can apply to several departments simultaneously, check out which depts better fit your profile! Here is the call for our Department of Medical Biochemistry and Biophysics ki.varbi.com/what:job/jobID…
Come and join us! Start your group at Karolinska Institutet @karolinskainst! news.ki.se/ki-to-recruit-…
The secret to how nucleosomes shape the genome | Journal Club | PNAS pnas.org/post/journal-c…
Excited to attend and speak at the grc.org/neurotrophic-m… about our work on NGF receptor TrkA @YalePharm @YaleMed! Dr. Shailesh Kumar from my lab is also presenting a poster. Looking forward to hearing about cool new discoveries in the area! @GordonConf
Check out this tour de force study by Sangwoo Park and his incredible team of collaborators. Biophysical properties of single nucleosomes are responsible for A and B compartments in cell nucleus.
"Native nucleosomes know where to go!” Our Condense-seq paper is now published in Nature! 📄 nature.com/articles/s4158… I’m deeply grateful to my PhD advisor @taekjip and our incredible collaborators @MuirLab , @binzmit , Erika Pearce, and Ben Garcia lab!!
jobs.boehringer-ingelheim.com/job/Ridgefield… I am hiring a postdoctoral fellow with expertise in molecular modeling and machine learning approaches to accelerate our growing predictive formulation development pipeline. DM me to know more
Our scientists with over 150 collaborators have released the largest functional map and wiring diagram of the brain to date – seven years in the making. Today’s 1.6 petabyte release marks a historic day for neuroscience. This moonshot milestone will further efforts towards…
How does the brain work? Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵
A big step forward for biomolecular ultrasound! 🔊 Congrats @bgheiles, @DMarescalab at @tudelft and collaborators! #gasvesicles
A new method reported in Science allows the generation of 3D ultrasound images of gene expression and 2D ultrasound images of capillary vessels. The approach enables fast, deep, and volumetric imaging of living opaque organs labeled with echogenic reporters. Learn more in this…
Thank you @Hypothesisfund and Yamuna Krishnan for this opportunity to shed “light” on membrane contact sites! Very honored to be a part of this mechanism and congratulations to my fellow awardees. Can’t wait to start this scientific adventure in my lab @YalePharm @YaleMed!
4/ With a 'molecular scalpel'🔪 to 'biopsy' membrane sites where cells/organoids make contact, Awardee @moitrayee_lab's research may reveal new insights into cellular processes & disease development (e.g. ALS). 🎉Congrats Dr. Bhattacharyya! @Yale 🙏#HFScout Yamuna Krishnan
Thrilled to share that my work from postdoctoral research has been published in @Nature . Huge thanks to my mentor Dr. Edward Twomey, and collaborators Elisa Carrillo and Prof. Vasanthi Jayaraman. nature.com/articles/s4158…
Join us in welcoming our next 2025 Pharmacology Seminar Series speaker, Susan Shao (@sshaolab). She will be presenting her work at 12 pm on Thursday, March 27th in the Brady Auditorium.
Thrilled to share our latest work published in @CellCellPress: Turnover Atlas of Proteome and Phosphoproteome Across Mouse Tissues and Brain Regions! cell.com/cell/abstract/… @Yanshen73854711 @JunminPengLab @euforna @YaleMed @YalePharm @CancerYale @HUPO #Proteomics #TeamMassSpec
Congratulations @Yanshen73854711!
Great Cell paper from Yansheng: cell.com/cell/fulltext/…
Excited to share our latest work on songbirds showing dopamine guides learning of natural behavior nature.com/articles/s4158… Congrats to @JonathanKasdin Alison Duffy Nathan Nadler @pantamallion @alfairhall @neuro_kim ! @ZuckermanBrain @Columbia @GoogleDeepMind @UW
Our new preprint is out＠bioRxiv: biorxiv.org/content/10.110… @MasaAShimazoe et al. reveal that linker histone H1 acts as a liquid-like "glue" to organize chromatin in living cells. 🎉 Fantastic collab with @rcollepardo, Charlie Phillips, @janhuemar and others—huge thanks! 🙌 1/2
Very excited to host Dr. Stephen Sligar this Thursday! Anyone doing membrane protein biophysics will immediately recognize his immense contributions in enabling reconstitution of membrane proteins in lipid nanodiscs and subsequent applications! Hope to see many of you there!
Join us in welcoming our next 2025 Pharmacology Seminar Series speaker, Stephen Sligar. He will be presenting his work at 12 pm on Thursday, February 27th in the Brady Auditorium.
Single-molecule live-cell RNA imaging with CRISPR–Csm go.nature.com/3EJPKsM
Thrilled (and relieved) to finally have this review by Arianna, Zeyi, and Kaitlyn out! Everything you've ever wanted to know about genetic code expansion in mammalian cells! pubs.acs.org/doi/10.1021/ac…