Sangwoo Park
@RealSangwooPark
Chromatin Biophysicist at Dana-Farber Cancer Institute.
"Native nucleosomes know where to go!” Our Condense-seq paper is now published in Nature! 📄 nature.com/articles/s4158… I’m deeply grateful to my PhD advisor @taekjip and our incredible collaborators @MuirLab , @binzmit , Erika Pearce, and Ben Garcia lab!!
New Online! Nucleosomes as blueprints of genome architecture bit.ly/4mM6wsO
The secret to how nucleosomes shape the genome | Journal Club | PNAS pnas.org/post/journal-c…
Commemorate the life and science of our dear departed colleague Jon Widom - this Thurs May 15 1230 pm in Pancoe Auditorium @NUmolbiosci @NorthwesternU - our distinguished Widom Lecturer is Prof. Lucy Bai @penn_state - Chromatin Accessibility and the 3D Genome
Latest #CDlab paper now in @NatureNano: nature.com/articles/s4156… Here 1st author @MembraneMachine showed that the protein Dynamin A can act as (single-component!) division machine to split a dumbbell-shaped liposome into two daughter vesicles!
Excited to have the final part of my graduate work from the @Kadochlab @DanaFarber @DanaFarberNews out today in @CellCellPress, where we dissect the (exciting!) role of ARID1A and ARID1B, two of the most mutated mSWI/SNF complex subunits! cell.com/cell/fulltext/…
My first 1st author paper is finally out! 😭 Thank you so much for my PhD advisor @taekjip, Greg, and my wonderful collaborator, Giovanni! doi.org/10.1093/nar/gk…
In @NatureRevGenet today, we discuss recent advances in computational methods for #3Dgenome analysis, pointing to an integrative future. Apologies for any missed refs. Joint w/ @NCITomMisteli @faucla @zocean636 @LoreBonimba @muyu_wendy_yang. @4DNucleome nature.com/articles/s4157…
Congratulations to @FreddyMValencia and @akshaysci on their newest study, just published in @NatureGenet ! Beautiful analysis highlighting that #SWISNF /#BAFcomplex genes are the most frequently perturbed gene classes in #neurodevelopmental disorders. nature.com/articles/s4158…
Congratulations to our @ajinkyapatil00 on an absolutely outstanding thesis defense yesterday!! @VirologyHarvard @harvardmed @DanaFarber We are so proud of you and are going to miss you very much! 🎉💯! @kadochlab @CKadoch
Congratulations, @kristin_qian !!
An honor to hood @kristin_qian in today’s @BBS_Harvard @harvardmed doctoral hooding ceremony just a few weeks after her beautiful thesis defense! Congratulations, Dr. Kristin Qian! @kadochlab
Molecule hibiscus nearly finished 🌺 #summerart #sciart #chemtwitter
.@CKadoch (@DanaFarber) kicking off the afternoon session with ‘Structure and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Health and Disease’ @JHU_BDPs
What is the 3D structure of chromatin condensed by the Polycomb repressive complex 1 (PRC1)? We determined it using #cryoET. Led by @MichaUckelmann from the @DavidovichLab in collaboration with @demarco_lab. @EMBLAustralia @MonashBDI @CryoEM_Monash biorxiv.org/content/10.110…
So excited to be celebrating @kristin_qian today as she defends her exciting @BBS_Harvard @harvardmed thesis work in our lab at @DanaFarber ! Congrats, Kristin!!! We are all so proud of you! 🎉🎉🥂
CAR T-cell therapies have opened a new era in the treatment of cancer, yet these therapies can lose potency over time. New research explains why. hvrd.me/u8bL50NJAM3
Next up at @AACR #AACR23 is @ajinkyapatil00 from @kadochlab @harvardmed #AACR Scholar-in-Training award winner presenting his exciting new work on #mSWISNF #BAF complexes! #chromatin #cancer
Looking to study chromatin interactomes with proximity labeling? Check out our new paper in @Nature, where we combine our split-intein expertise with uMap technology from the @MacMillan_Lab to map the microenvironment of chromatin state changes. nature.com/articles/s4158…