Matthias Mann Lab
@labs_mann
The Mann Lab is a pioneer in mass spectrometry-based proteomics. Tweets represent personal views from lab members and Matthias Mann @MPI_Biochem and @UCPH_CPR.
Thank you Matthias @labs_mann for your visionary leadership and for creating a scientific family that continues to push boundaries. Congratulations from all members and looking forward to the future! #MS #Proteomics #20Years
🎉Congratulations to Matthias Mann on 20 years leading Proteomics & Signal Transduction at MPI of Biochemistry! Two decades of groundbreaking mass spectrometry research and training excellent future scientists. #MS #Proteomics #Science @labs_mann
Don't forget to connect with our team members at #ASMS2025. Talks and poster line-up below 👇
Heading to #ASMS2025? Our team will be there showcasing our latest breakthroughs in mass spectrometry! Don't miss the chance to connect with @labs_mann team members and discover the cutting-edge work we have been developing.
Huge congrats to @atul_deshmukh and team on this Cell paper! Cutting-edge MS-based proteomics across >120 individuals shows fasting muscle proteome predicts insulin sensitivity & reveals selective resistance patterns. New perspective for diabetes medicine!
Thrilled to share that our preprint mapping proteomic & phosphoproteomic signatures of NGT, T2D, males & females — before and after hyperinsulinemic-euglycemic clamp — is now accepted in Cell. Thank you to everyone involved! doi.org/10.1016/j.cell…
Our collaboration with @ErnstLengyel and team is out in @Nature. The study shows that blocking NNMT reprograms cancer-associated fibroblasts & restores immune response against ovarian cancer. Happy to see that our earlier research contributed to this breakthrough. Congrats all!
New in @Nature: Drs. @ErnstLengyel, @JannaHeide, @OvCa_UChicago & team discovered a first-of-its-kind NNMT inhibitor that reprograms cancer-associated fibroblasts & restores immune response in ovarian cancer, marking a major step toward better therapies. nature.com/articles/s4158…
Apply today and be part of inspiring science! Deadline July 23rd! #Proteomics #Postdocs
My lab is hiring a postdoc for translational research in inflammatory skin diseases using cutting-edge proteomics Join us @MPI_Biochem. All the infos here 🔍 mpg.de/24950076/postd… Apply until July 23. Please RT.
Excited to share our new preprint! Collaborating with Dr Maitra @Aiims1742 and his outstanding team at @MDAndersonNews and the Nebraska Rapid Autopsy Program, we used AI-driven Deep Visual Proteomics to uncover early molecular shifts in pancreatic cancer precursor lesions.…
New @biorxivpreprint ! With Dr. Maitra @Aiims1742 (@MDAndersonNews) & Nebraska Rapid Autopsy Program, we used AI-powered Deep Visual Proteomics to map early molecular changes in pancreatic cancer precursor lesions. Read: bit.ly/4nAqPK8 #SpatialMedicine #PDAC
Congratulations Vincent @_VAlbrecht - well done!
After many hours in the lab and tackling tricky research questions, it's now time to celebrate. 🥳 Congratulations on your PhD, Vincent @labs_mann. We wish you every success in your future career. @_VAlbrecht
Don't forget to check out Marvin Thielert's poster 773 on single cell proteomics at #ASMS2025! #SingleCellProteomics
Protein digestion in 200 nL on solid-phase tips: SPEC enables low-input proteomics—even with SDS/SDC at high levels. From FFPE and muscle to high throughput plasma. SPEC is a universal and Evosep-compatible protocol. biorxiv.org/content/10.110…
Nano-scale, mega-impact: nanoPhos delivers 100× phosphoproteomics sensitivity, 70k sites from 1µg, 8k from 10ng! Powered by SPEC, it enables phosphoDVP: deep spatial phosphoproteomics from 1000 neurons, hitting 17k sites, a game changer for spatial omics. biorxiv.org/content/10.110…
New approach tackles studying rare pediatric diseases! We developed an ontology-guided clustering framework using SNOMED CT to analyze proteomes from 1,140 children across 394 conditions - enabling meaningful insights even with tiny patient numbers! embopress.org/doi/full/10.10…
