Joycelyn Tan
@joycelyntsi
Postdoc @lydfinley lab @MSKCancerCenter interested in cellular metabolism and mitochondria 🧫 | Previously PhD @Cambridge_Uni @IMS_MRL
Beyond excited to share my first paper from my PhD @DPhaz Lab @IMS_MRL now out in @embojournal! Special thanks to Sam from @TVPLab and @dougall_norris for co-leading this project with me. We found that many cell culture models, despite living in 18% oxygen, are hypoxic! 🧵below:…
Excited to share our opinion piece on why current standard cell culture practices deserve more consideration - with implications on cell metabolism and beyond! We focus in particular on nutrient and oxygen availability. A pleasure to work with @JasonRCantor lab! @DPhaz @IMS_MRL
happy to share our forum now online @Cell_Metabolism! fun for us (@guytochondria & myself) to collaborate with @DPhaz @joycelyntsi, and Sam in putting together what we hope will be a useful piece for the broad metabolism community re: in vitro modeling! cell.com/cell-metabolis…
Postdocs: we want to start a NYC "Postdoc Night Science" forum where fellows meet monthly for a drink and fun practicing the creative process together with chalk talks and brainstorming. Sign up here: docs.google.com/forms/d/1V4_c2… @KelseyRMonson is helping and we need more volunteers!
I'm excited to share our latest story from the @lydfinley lab, where we show that it's not just whether cells take up nutrients that matters, but how and where those metabolites are used . Out now in @NatMetabolism: rdcu.be/ejFTs 1/
We have a postdoc position available in our team to undertake a UKRI-funded project to develop a new cultured skeletal muscle model for studying glc metabolism and insulin action. jobs.cam.ac.uk/job/50597/ @IMS_MRL Please RT. Please email if interested.
Very excited to finally share our work using subcellular proteomics to look at insulin-stimulated protein movement in adipocytes! 🧵below: (1/5) biorxiv.org/content/10.110… @DPhaz @IMS_MRL
Our latest preprint identifies (targetable!) metabolic programs intrinsic to different cancer cell states in rhabdomyosarcoma, out just in time for @kiparas21's thesis defense tomorrow!
PAX3-FOXO1 drives targetable cell state-dependent metabolic vulnerabilities in rhabdomyosarcoma biorxiv.org/cgi/content/sh… #biorxiv_cancer
no PhD in history has ever needed to say this before
Guys, I adore your enthusiasm towards reading my thesis, but please stop requesting it on the university’s depository. I can’t lift the embargo as publishers prefer/require it and I’ve been getting hundreds of emails per day for over a month. I’m really sorry!
Oncometabolites at the crossroads of genetic, epigenetic and ecological alterations in cancer nature.com/articles/s4141…
19th October 2024 Watching autumn leave. @stjohnscam
Check out this #Resipher feature on @TheScientistLLC! It outlines the experience that @joycelyntsi, cellular biologist at Memorial Sloan Kettering Cancer Center, had with using the device to measure #OxygenConsumption rate. the-scientist.com/a-simple-cell-…
BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
Hi #cancer #metabolism twitter. New review from @CognetGuillaume: science.org/doi/10.1126/sc…. Has long been understood that tumors experience metabolic stress due to nutrient limitation in the tumor microenvironment. 1/7
Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. MouseMapper showed obesity-induced changes in facial nerves & body-wide inflammation 👉🏼🧵biorxiv.org/content/10.110…
We are looking for a Postdoc to investigate novel genes that regulate insulin-stimulated glucose transport (tinyurl.com/ycarykzh). MRC-funded collaboration with O'Rahilly (@StephenORahilly) @IMS_MRL & Langenberg groups (QMUL). Please RT. Link: tinyurl.com/57ea9p3f
We @IMS_MRL @Cambridge_Uni are looking to significantly expand our computational science capabilities in metabolism & are recruiting 3 senior bioinformaticians. Please contact me for more info. Deadline Aug 2. Please share widely nature.com/naturecareers/…
One of the PhD students in my department made this. I can´t get over how cute this is.😭 #Crochet #CellBiology #Microscopy
Thanks to this funding scheme, we will be shortly looking for a post-doc to run the metabolomics part of the project, in collaboration with a wonderful team of scientists and the metabolomics facility @CECAD_ Please write to me for more information!
A big day for the Cologne mitochondrial community! The #CRC1218 is funded by the DFG for another four years! This collaborative grant will foster exciting discoveries on how #mitochondria regulate cell function. Thank you to all colleagues, postdocs, and PhD students involved.
Thank you @NathalieMazure for the thoughtful commentary on our work, and for putting these findings into context alongside other preceding studies on oxygen in cell culture! 🧫 embopress.org/doi/full/10.10…
Presenting metabolomics analyses: what is in a number? embopress.org/doi/full/10.10… @JohannesMeiser and I wrote this short piece to raise awareness about how present metabolomics data. We hope you will find it useful. Any comment is welcome! thanks @DanielKlimmeck for the support!