bioRxiv Cancer Bio

A novel, high-density CRISPR activation platform for mapping cancer dependencies and resistance pathways ex vivo and in vivo biorxiv.org/content/10.110… #biorxiv_cancer

Capillary constrictions prime cancer cell tumorigenicity through PIEZO1 biorxiv.org/content/10.110… #biorxiv_cancer

The 3D genome of pediatric B-cell precursor acute lymphoblastic leukemia biorxiv.org/content/10.110… #biorxiv_cancer

Uttroside B, a US FDA-designated Orphan drug, mitigates thedevelopment of hepatocellular carcinoma and its pulmonary metastasis via ... biorxiv.org/content/10.110… #biorxiv_cancer

Targeting nucleolin facilitates the development of blood-tumor barrier-penetrating and glioblastoma-specific PROTACs biorxiv.org/content/10.110… #biorxiv_cancer

RNA Methylation dynamics regulates cancer stemness through modulation of cell migration and cell proliferation in the spheroidal ... biorxiv.org/content/10.110… #biorxiv_cancer

Baseline expression of c-Myc defines the tissue specificity of oncogenic K-Ras biorxiv.org/content/10.110… #biorxiv_cancer

RUNX2 inhibition disrupts a PAX3::FOXO1-RUNX2 feed-forward loop and dismantles oncogenic gene programs in fusion-positive rhabdomyosarcoma biorxiv.org/content/10.110… #biorxiv_cancer

Integrated single-nuclei and spatial transcriptomic profiling of human sacrococcygeal teratomas reveals heterogeneity in cellular ... biorxiv.org/content/10.110… #biorxiv_cancer

Bisantrene potentiates tyrosine kinase inhibitor activity in clear cell renal cell carcinoma biorxiv.org/content/10.110… #biorxiv_cancer

Targeted disruption of Oncogenic Biosphere: A Paradigm Shift Beyond Cancer Cell-Centric Therapies biorxiv.org/content/10.110… #biorxiv_cancer

microRNA-21 promotes dysregulated lipid metabolism and hepatocellular carcinoma biorxiv.org/content/10.110… #biorxiv_cancer

Actin-modulated nuclear shape controls adaptive reprogramming in cancer-associated fibroblasts biorxiv.org/content/10.110… #biorxiv_cancer

Endocrine therapy induces oxidative stress in ER+ breast cancer that sensitizes persister cells to ferroptosis biorxiv.org/content/10.110… #biorxiv_cancer

An Atomic Force Microscopic analysis of Exosomes derived from Tumor Associated pluripotent Mesenchymal Stem Cells. biorxiv.org/content/10.110… #biorxiv_cancer

Engineered Extracellular Vesicles Enriched with miR-214 Enhance the Efficacy of Chemotherapy for Ovarian Cancer biorxiv.org/content/10.110… #biorxiv_cancer

Transcriptional Circuitry in HGSOC: A Dynamic Three-State Model Informed by a Living Biobank of Purified Tumour Fractions biorxiv.org/content/10.110… #biorxiv_cancer

A Step-wise, Deterministic and Fatal Mouse Model of Myeloid Neoplasm with Spontaneous Acquisition of Patient-relevant RTK-RAS Mutations biorxiv.org/content/10.110… #biorxiv_cancer

Oxidative Stress, Hypoxia and Cellular Metabolism: Unraveling the Effects of Fentanyl on Lung Cancer Cells biorxiv.org/content/10.110… #biorxiv_cancer

Mutational and Expression Profile of ZNF217, ZNF750, ZNF703 Zinc Finger Genes in Kenya Women diagnosed with Breast Cancer biorxiv.org/content/10.110… #biorxiv_cancer