Daniel Fazakerley
@DPhaz
Group leader at @IMS_MRL researching insulin action and glucose transporter traffic.
Please check out Liv's preprint and thread below!
Very excited to finally share our work using subcellular proteomics to look at insulin-stimulated protein movement in adipocytes! 🧵below: (1/5) biorxiv.org/content/10.110… @DPhaz @IMS_MRL
Excited to share our opinion piece on why current standard cell culture practices deserve more consideration - with implications on cell metabolism and beyond! We focus in particular on nutrient and oxygen availability. A pleasure to work with @JasonRCantor lab! @DPhaz @IMS_MRL
happy to share our forum now online @Cell_Metabolism! fun for us (@guytochondria & myself) to collaborate with @DPhaz @joycelyntsi, and Sam in putting together what we hope will be a useful piece for the broad metabolism community re: in vitro modeling! cell.com/cell-metabolis…
Interested in a pretty cool postdoc project with Dr @HenningLanger and I? 🔥
Hey Muscle And Metabolism Folks on Twitter, @LykkeSylow and I are looking for a Postdoc who is interested in applying for a prestigious @DDEA_Denmark fellowship with us. More details in the picture attached. Please share widely! @MYOTWlTTER
Uri is a brilliant and creative scientist working on super important and challenging research questions - he’s also a bloody nice guy. I hope his message spreads wide and far to highlight the absolute madness many of our US colleagues are going through at the moment. Please RT 🙏
My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15
Thanks to our amazing collaborators: @TVPLab @ThomasKriegLab @Mito_Redox @DPhaz and @AstraZeneca teams. Proud of this @TheBHF -supported science!
🚨 New paper out from us, reveals a novel role for mitochondrial RET-ROS in #HFpEF. 🧬 ND6 mutation ➡️ 🫀 Hypertrophy 💔 Diastolic dysfunction 🏃♂️ ↓ Exercise capacity 💪 ↑ Lean mass 🍩 HFD worsened metabolism ✅ Exercise reversed many effects! doi.org/10.1152/ajphea…
🚨We're hiring! Come join us in Belfast at @WWIEM_QUB 🔬 We're looking for a postdoc to help uncover the mechanism behind a novel genetic cause of heart failure, funded by @TheBHF. Apply here👉 hrwebapp.qub.ac.uk/tlive_webrecru… Questions? Reach out via X/LinkedIn/Email! @ProfDavidGrieve
Check out our latest paper published in Diabetes @ADA_DiabetesPro Analysis of multiple insulin actions in single muscle fibres from insulin resistant mice reveals selective defect in endogenous GLUT4 translocation diabetesjournals.org/diabetes/artic…
🚨 pleased to share a new preprint made possible through a great collaboration with the @melissa_skala & @SeanPalecek labs! can medium composition impact the behavior of hPSC-derived cardiomyocytes? Andy and Aaron co-led efforts to tackle this Q w/HPLM! tinyurl.com/ux2arjw8
excited for a weekend of great science #ASBMB25! if you're in CHI, I encourage you to check out a session that @Derpology & I co-organized, Sat @ 930 (W176): events.rdmobile.com/Sessions/Detai… +a short talk from Kyle (Sun @ 9, W178), and posters from Kim, Kyle, & Gavin (Sun @ 430, W375c)!
Interested in undertaking a PhD to contribute to the understanding of the links between insulin resistance and cardiovascular disease? Apply to join my lab at the RVC with this fully-funded PhD studentship.
🎓 Fully-funded PhD studentship available. Apply now for a PhD studentship to learn from experts who produce cutting-edge research and are published in top academic journals. Fully-funded for UK 'Home' students. ➡️ rvc.ac.uk/phd
@IMS_MRL @Cambridge_Uni full-time taught MPhil in Obesity, Endocrinology and Metabolism for 2025/2026 Application deadline 4th April!!! High quality postgrad training in physiology & pathophysiology of energy balance & metabolism. 🛜 mrl.ims.cam.ac.uk/study-us/taugh…
New! Online now: Seeing the world through the eyes of cultured cells dlvr.it/TJW8zZ
We have a postdoc position available in our team to undertake a UKRI-funded project to develop a new cultured skeletal muscle model for studying glc metabolism and insulin action. jobs.cam.ac.uk/job/50597/ @IMS_MRL Please RT. Please email if interested.
happy to share our forum now online @Cell_Metabolism! fun for us (@guytochondria & myself) to collaborate with @DPhaz @joycelyntsi, and Sam in putting together what we hope will be a useful piece for the broad metabolism community re: in vitro modeling! cell.com/cell-metabolis…
Anyone interested in working with me @IMS_MRL @Cambridge_Uni on how AMGEN's new obesity drug works? I have a 3 year postdoc position available! Deadline March 31st! please share jobs.cam.ac.uk/job/50529/
🚨Long term postdoc position available on the reconstitution of lipid kinases!🚨 Do you have a passion for protein reconstitution and lipid signalling? You will reconstitute lipid kinases to determine their kinetic regulation. jobs.ac.uk/job/DLW981/res…
I’m excited to share the first paper from my lab, out today in @ScienceAdvances! science.org/doi/10.1126/sc… We uncover a new family of phospholipid remodelling enzymes. A 🧵:
excited to share a new preprint from our lab! led by the outstanding (& recently minted PhD) @thebioKIMist, we first uncover a basis for conditional HK2 essentiality in HPLM - leveraging this dependence➡️distinct rationale underlying the Warburg Effect! biorxiv.org/content/10.110…