Broad Institute (@broadinstitute)

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Broad Institute@broadinstitute · 19 h

Join us on Thursday, August 14 at 6 pm ET in Cambridge, MA, or virtually for a Broad Discovery Series talk with @soumya_boston, “Arthritis, autoimmunity, and how the genome works.” Register: broadinstitute.swoogo.com/DiscoverySerie…

broadinstitute's tweet image. Join us on Thursday, August 14 at 6 pm ET in Cambridge, MA, or virtually for a Broad Discovery Series talk with @soumya_boston, “Arthritis, autoimmunity, and how the genome works.” Register: broadinstitute.swoogo.com/DiscoverySerie…

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Eric and Wendy Schmidt Center@Schmidt_Center · 21 h

🏅 Congratulations to @Schmidt_Center postdoctoral fellow @bdanubius on being selected as an award recipient of the 2025 @NIH Outstanding Scholars in Neuroscience Award Program (OSNAP) earlier this month! Learn more: nimh.nih.gov/research/resea…. Oh, snap indeed. @broadinstitute

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Blainey Lab@BlaineyLab · 20 h

Out now in @NatureMicrobiol @beccajcarlson and our lab collab w/ Rob Davey's lab @neidl on high-content image-based perturbational screening for regulators of Ebola virus infection @broadinstitute nature.com/articles/s4156…

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Broad Institute@broadinstitute · 22 h

Using an image-based screening method, Broad and Boston University researchers found potential new drug targets for reducing Ebola infection severity, uncovering human genes that, when silenced, impaired Ebola’s ability to replicate. broad.io/Ebola-News-0724

broadinstitute's tweet image. Using an image-based screening method, Broad and Boston University researchers found potential new drug targets for reducing Ebola infection severity, uncovering human genes that, when silenced, impaired Ebola’s ability to replicate. broad.io/Ebola-News-0724

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Eric Topol@EricTopol · Jul 21

One-shot prime genome editing ("CRISPR 3.0") of the brain in vivo corrected AHC, a rare genetic disorder, in the mouse model. Another big step forward in the genome editing field. @CellCellPress @davidrliu and colleagues cell.com/cell/fulltext/…

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David R. Liu@davidrliu · Jul 21

Today in @CellCellPress we report the use of prime editing to correct several mutations that cause alternating hemiplegia of childhood (AHC), a rare and devastating neurodevelopmental disorder, in patient-derived cells and in two mouse models. drive.google.com/file/d/1ibC50t… 1/10

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Broad Institute@broadinstitute · Jul 21

Partnership between @davidrliu, @jacksonlab, and rare disease group @RAREH0pe leads to first use of prime editing for a brain disease that reduced symptoms, extended lifespan in mice, offering hope for other rare genetic diseases. broad.io/Prime-AHC

broadinstitute's tweet image. Partnership between @davidrliu, @jacksonlab, and rare disease group @RAREH0pe leads to first use of prime editing for a brain disease that reduced symptoms, extended lifespan in mice, offering hope for other rare genetic diseases. broad.io/Prime-AHC

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Eric and Wendy Schmidt Center@Schmidt_Center · Jul 18

.@Schmidt_Center fellows Divya Shyamal & @JiaqiZhangVic, with senior author Caroline Uhler, introduce a new framework for designing experiments with treatment combos, scaling discovery of complex interactions in biology and medicine. 🔗 news.mit.edu/2025/more-effi… @broadinstitute

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Broad Institute@broadinstitute · Jul 18

Join me for this lecture to find out how we use genomics to decipher #autoimmunity and #rheumatoid arthritis

BBroad Institute@broadinstitute · Jul 16

Join us on Thursday, August 14 at 6 PM ET in Cambridge, MA – or online – for a Broad Discovery Series talk with @soumya_boston: “Arthritis, autoimmunity, and how the genome works.” Register: broadinstitute.swoogo.com/DiscoverySerie… #ScienceTalks

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Broad Institute@broadinstitute · Jul 17

I've always found @soumya_boston's research to be absolutely fascinating, and I'm excited to bring him on-stage for the next talk in the @broadinstitute's Broad Discovery Series. Join us in-person or online on 8/14!

BBroad Institute@broadinstitute · Jul 16

Join us on Thursday, August 14 at 6 PM ET in Cambridge, MA – or online – for a Broad Discovery Series talk with @soumya_boston: “Arthritis, autoimmunity, and how the genome works.” Register: broadinstitute.swoogo.com/DiscoverySerie… #ScienceTalks

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Broad Institute@broadinstitute · Jul 17

Great opportunity to hear from our very own @BrighamWomens researcher @soumya_boston!

BBroad Institute@broadinstitute · Jul 16

Join us on Thursday, August 14 at 6 PM ET in Cambridge, MA – or online – for a Broad Discovery Series talk with @soumya_boston: “Arthritis, autoimmunity, and how the genome works.” Register: broadinstitute.swoogo.com/DiscoverySerie… #ScienceTalks

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Vijay Sankaran@bloodgenes · Jul 17

Delighted to have our preprint led by @lvchosen1 up: Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells biorxiv.org/content/10.110… 🧵 below ...

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Broad Institute@broadinstitute · Jul 17

We are thrilled to announce that Seth Klarman will become the next Chair of the Broad Institute Board of Directors, succeeding Eric Schmidt. We also welcome Aviv Regev as a new member of the Board. broad.io/Klarman-Board

broadinstitute's tweet image. We are thrilled to announce that Seth Klarman will become the next Chair of the Broad Institute Board of Directors, succeeding Eric Schmidt. We also welcome Aviv Regev as a new member of the Board. broad.io/Klarman-Board

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Broad Institute@broadinstitute · Jul 16

Join us on Thursday, August 14 at 6 PM ET in Cambridge, MA – or online – for a Broad Discovery Series talk with @soumya_boston: “Arthritis, autoimmunity, and how the genome works.” Register: broadinstitute.swoogo.com/DiscoverySerie… #ScienceTalks

broadinstitute's tweet image. Join us on Thursday, August 14 at 6 PM ET in Cambridge, MA – or online – for a Broad Discovery Series talk with @soumya_boston: “Arthritis, autoimmunity, and how the genome works.” Register: broadinstitute.swoogo.com/DiscoverySerie… #ScienceTalks

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So Mi Jemma Cho@somijemmacho · Jul 14

[1/10] At last, @MassGenBrigham x @MountSinaiNYC x @PennMedicine x @VUMChealth collaboration on external validation of the @AHAScience's PREVENT is now out in @JACCJournals! sciencedirect.com/science/articl…

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Pradeep Natarajan@pnatarajanmd · Jul 14

An absolute risk generalizable risk calculator is challenging. Led by @somijemmacho, evaluating AHA PREVENT across 4 academic health systems, we found similar discrimination but variable calibration. A universal absolute risk threshold may not suitably guide.…

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Nature Biotechnology@NatureBiotech · Jul 15

The July issue is live nature.com/nbt/volumes/43… On the cover, Chen et al. have developed a precise chemo-enzymatic method to synthesize and modify protein-coding mRNA to optimize functionality and pharmacokinetics go.nature.com/47EXbfq

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Romanos SP@RomanosSP · Jul 8

Our paper on establishing targeted therapy for patients with myeloma and 1q+ is out in @BloodPortfolio! w/ Liz Lightbody, Mairead Reidy, @gaddyg @IrenemGhobrial and Salomon Manier @DanaFarber @broadinstitute #mmsm ashpublications.org/blood/article-… 1/

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Pradeep Natarajan@pnatarajanmd · Jul 3

Our study led by R. Bhattacharya & @cmarnell92 shows that, when simultaneously considering clinical, laboratory, and genetic risk factors for incident CAD prediction, the top 2 model explanatory factors are: 1. Hypertension 2. CAD polygenic risk score ahajournals.org/doi/10.1161/CI……

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Anna Greka@AnnaGreka · Jul 3

Delighted to share our latest, expertly led by @KatlynGabriel_ and @ChoahK: FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses Impactful work with therapeutic potential by our @GrekaLab team at @broadinstitute! science.org/doi/10.1126/sc…

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