Romanos SP
@RomanosSP
MD-PhD, Instructor at @DanaFarber and @BroadInstitute working on Multiple Myeloma and Waldenstrom's genomics/immunology. Founder @PredictaBiosci 🏳️🌈(he/him)
Let's walk through what we found in our new study using single-cell RNA-seq on tumor and immune cells from pts w/ asymptomatic Waldenstrom's Macroglobulinemia - out now in @NatureComms! W/ @Yoshi_konnykid @IrenemGhobrial @gaddyg #wmsm #mmsm nature.com/articles/s4146… 1/
A historic day for myeloma!! After 5 decades of research. European Commission / EMA approves Daratumumab as the first ever approved treatment for high risk smoldering myeloma based on the results of the AQUILA trial. @thanosdimop @PlasmaCellPete globenewswire.com/news-release/2…
Major Regulatory Milestone in MM: In response to an application by I2TEAMM and @IMFmyeloma, the European Medicines Agency has officially endorsed MRD as an early endpoint in clinical trials for Myeloma. This marks a transformative step forward in drug development !! @VincentRK
Happy to share our new work out today on @BloodPortfolio #Blood where we report CD38 loss as recurrent mechanisms of resistance to anti-CD38 antibody in multiple myeloma. Great collaboration between @MSKCancerCenter @MSK_DeptOfMed @UCalgary @HDMyeloma @MayoClinic #mmsm #wgs
Great step forward for patients with myeloma! IMS/IMWG recommending NGS for the identification of high-risk patients. Also noting many other high-risk genomic/transcriptomic etc. features, that could be incorporated in future iterations as more data becomes available. #mmsm
International Myeloma Society/International Myeloma Working Group Consensus Recommendations on the Definition of High-Risk Multiple Myeloma | Journal of Clinical Oncology ascopubs.org/doi/10.1200/JC…
Excited to share our work investigating the mutagenic impact of radiotherapy in hematological cancers out today in @BCD_AACR!! 🎉 Another study born from amazing collaborations across @MoffittNews @HDMyeloma @univmiami @MSKCancerCenter @MSK_DeptOfMed 💪 #lysm #wgs #RT #mmsm
This was a privilege to work on. Big thanks to all of our co-authors and collaborators for supporting the effort!
Excited to share our work investigating the mutagenic impact of radiotherapy in hematological cancers out today in @BCD_AACR!! 🎉 Another study born from amazing collaborations across @MoffittNews @HDMyeloma @univmiami @MSKCancerCenter @MSK_DeptOfMed 💪 #lysm #wgs #RT #mmsm
Great timing for this publication, as we discuss the need to improve the identification of patients with SMM at high risk of progression in light of yesterday’s ODAC meeting. Congrats @JbAlberge @ankitkdutta @andreapoletti19 @IrenemGhobrial @gaddyg and team #mmsm
1/ 🧵Check out our new study in @NatureGenet, which examines how precancerous conditions (MGUS/SMM) evolve into Multiple Myeloma, and offers new computational methods to predict progression risk and model cancer evolution. doi.org/10.1038/s41588…
At #IBC2025, we caught up with @RomanosSP (@DanaFarber) to hear the findings from a single-cell sequencing study evaluating tumor & immune cells in pts with MGUS, #SmolderingMyeloma & overt #myeloma. Click here to watch: 🎥 ow.ly/Ve6150VxZaC #MMSM #MultipleMyeloma #HemOnc