Dr. Stuti Mehta
@StutiMehtaR
midnight explorer. scientist.
Delighted to share our #NightScience tale: "A tetramer of BCL11A is required for stable protein production & fetal hemoglobin silencing," in @ScienceMagazine. Co-led by Zheng Ge, Yin Maolu, & me, here’s a tweetorial about our puzzle-solving adventure! 1/7 tinyurl.com/2tpaaua3
🧵 It's raining outside, perfect for some vibe coding... ☔ So I built something cool with @AnthropicAI's Claude Desktop! Introducing Claude Text Editor - edit ANY text, ANYWHERE on macOS with Claude's help. No more copy-paste gymnastics! 🚀
Join us for an exciting seminar on Dec 5, 2024, at 12 PM EST: Yifat Merbl (Weizmann Institute): "Proteasome Profiling: MAPPing the degradation landscape in health & disease." Gregory Michaud (Novartis): "Novel Molecular Glue Targets." …afarbertargetedproteindegradation.org
Hear hear
The vast majority over discoveries are low hanging fruit when they are made. The key to scientific progress is progressively making more fruit low-hanging. One of the deep problems we have in science is that we reward the people who pick the fruit rather than the ones who lower…
I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Bioeng Custom Lab Hardware Turn Key Genetic Design Please RT 💚
Wild if true!
There are so many weird Biology quirks that I somehow missed before and am only just finding now... Apparently translation can and *does* initiate from EVERY codon With the caveat that any codon other than the canonical AUG / GUG / UUG options induce transcription at such…
What is it like to transform an academic study into patient care? Drs. Vijay Sankaran (@bloodgenes) and Stuart Orkin from @harvardmed reflect on how the journey they took in creating the world’s first #CRISPR medicine for #SickleCellDisease. Learn more: bit.ly/3F6tOID
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis…
The timeless aesthetics of Indian women reading. Thread. An astounding frame capturing Rati Bartholomew reading "Thought", Old Delhi (1958) by Richard Bartholomew. © Estate of Richard Bartholomew via Museum of Fine Arts, Huston. 1/14
We hope that this will rewrite some basic ideas about macrophage specification and human HSCs.
Second preprint of the day. biorxiv.org/content/10.110…
Regulated GATA1 expression as a universal gene therapy for Diamond-Blackfan anemia dlvr.it/TH7gR5
Applications open for 6-week undergraduate summer training program 2025 at Param Hansa Center for Computational Oncology, @iiscbangalore. Deadline: Jan 31, 2025. forms.gle/XcdsGXrpsAdMc6… @biopatrika @IndiaBioscience @DynamicsLiving @SMBMathOnco @BE_IISc @cphms_aic @rakeshthejoy
RIP President Jimmy Carter For years you have been my go-to example of how immunotherapy has revolutionized our approach to some cancers I still remember the first time I saw a case of melanoma vanish entirely — not through chemo but unfettered T cells web.archive.org/web/2016020406…
It’s crazy how talking with a science buddy is simultaneously what’s most likely to move the project forward and the thing that’s least prioritized in our schedule.
Many people talk about the 'Golden Age of Antibiotics' but I hadn't seen it visualized properly. How abundant was antibiotic development during that time period? How many types of antibiotics were developed? So I visualized it myself!
The good idea comes when one person feels comfortable enough to say something that might make them look stupid and their friend is open enough to recognize its potential.
Can't wait to dig into this one, congrats Rowe lab!
Just in time for #ASH24, our latest is online: nature.com/articles/s4159…