Scott Soleimanpour

Type 2 diabetes is often considered a protein misfolding disease. But where are these toxic proteins found? 🤔 🚨In new work out today in @NatMetabolism, we show that mitochondrial protein misfolding (yes mitos🤯) leads to beta cell damage in T2D. 🚨 nature.com/articles/s4225… 1/n

Excited to share the latest @UMich Caswell Diabetes Institute Annual Report! 🎉 Discover how we're advancing #diabetes research, education, and care - and reach out if you'd like to partner with us! diabetes.med.umich.edu

The Division of Metabolism, Endocrinology, & Diabetes (MEND) is seeking an optimistic, collaborative, and creative chief to lead the division in clinical care, research, and education. Learn more and apply: medschool.umich.edu/departments/in…

Wow, fatty acid oxidation in neurons! Time to update the textbooks?!

My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15

My absolute favorite lab tradition - champagne (mimosa) toasts to a newly accepted paper, celebrating @JinLi33877470's new story! Can't wait to share when it's out in print! 🍾🥳

Today, the annual Stefan Fajans Lecture (the highest profile @UMich Diabetes seminar) was delivered by @drmohanv, whose presentation was a tour de force on MODY and T2D in India with comparisons worldwide. Thank you Dr. Mohan and @DMDSC for your illuminating and important work!

First Pan India MONOGENIC DIABETES (MODY) paper published today. Thank you and congratulations to all collaborators and coauthors from across India. Very special day for me as today as with Baba’s Grace, I am at University of Michigan to receive the award and deliver the Stefan…

PanKbase #ADA2025 spotlight: PI @annagloyn presents Sun. the 22nd at 2pm CDT. Session: Genetic Regulation of Beta-Cell Mass and Function in Humans: Lessons from GWAS and Rare Genetics. Her talk: "Integrating Multiomic Data to Understand Complex Gene Regulatory Networks in Islets"

As we all age, we accumulate mtDNA mutations, but what underlies this hockey stick pattern? See our new pre-print: we treat mtDNA SNV burden as a "trait" and use GWAS to uncover the mechanism in blood. Led by newly minted MD-PhD @rahulg603 w/ @LabNeale. shorturl.at/IqYY8

I discuss the urgent crisis from the loss of federal support of science in the US and recent clinical gene editing breakthroughs with @WalterIsaacson & @amanpour on @AmanpourCoPBS, airing on @PBS tonight at 11 pm ET, and on @cnni earlier today. Pls share! youtube.com/watch?v=8YhJM6…

Silencing mitochondrial gene expression in living cells | Science science.org/doi/10.1126/sc…. Wonderful that our paper is out now in Science. A big thanks to LD Cruz-Zaragoza and the team, @warscheidlab & @JakobsLab .

🚨Job Alert!🚨 @NatMetabolism seeks an Associate or Senior #Editor to join our team. If being a #Metabolism Editor is for you, and you are based in, or open to moving to New York or Shanghai, check out our #job posting below and apply before June 11th! springernature.wd3.myworkdayjobs.com/SpringerNature…

This is interesting, de novo serine biosynthesis is upregulated as an adaptive response during mitochondrial stress cell.com/cell-reports/f…

The Multidisciplinary Training Program in Basic Diabetes Research T32 at @umichmedicine is accepting applications from postdoctoral fellows interested in diabetes and metabolic disease research. Deadline May 16. Apply and learn more here: medschool.umich.edu/departments/in…

"Just some of the triumphs that have come from our robust biomedical research enterprise. NIDDK, as a reflection of work done across the entire NIH, is a prime example of government monies well spent" The 75th anniversary of @NIDDKgov @NIH diabetesjournals.org/care/article/d…