Kyle G Daniels

🚨 New Preprint 🚨 A continuous landscape of signaling encodes a corresponding landscape of CAR T cell phenotype How can we tune JAK/STAT signaling to create better immune cell therapies? doi.org/10.1101/2025.0…

Super exciting work from @GallowayLabMIT

We traveled to DC to talk to Congressional Staffers about the impact of @NIH @NIBIBgov funding. It enables us to develop synthetic biology tools to advance cell & genetic medicines for patients in need. REPOST to deliver the message that SCIENCE saves lives & makes America great!

Plasma proteomics links brain and immune system aging with healthspan and longevity nature.com/articles/s4159…

Excited to share that I’ve officially received the NIH/NCI Early-Stage K99/R00 award! So grateful for my mentors (Dr. Marcela Maus and Dr. Matthew Paszek), colleagues, and friends who’ve supported me. A slightly delayed but unforgettable birthday gift! 🎉 #K99R00 #NIH #MGH

My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15

Now that the lab has stuff in it, I’m looking for a postdoc. Must have: - Mouse experience (several years ideally) - Cell culture experience - An interest in T cells - Team player Bonus points for: - any flow experience - any scRNAseq exp (wet or dry) - CAR T manufacturing

@sara_mostafavi (@genentech ) & I (@Stanford) r excited to announce co-advised postdoc positions for candidates with deep expertise in ML for bio (especially sequence to function models, causal perturbational models & single cell models). See details below. Pls RT 1/

🌠 Announcing our latest awardees! 🤩 These talented scientists are uncovering how viruses infect cells, decoding cell behavior, and exploring the hidden biology in the ocean: bit.ly/HFAwardees. Meet the awardees & hear about their bold projects from our #HFScouts 👇 /1

Register for tomorrow's #SITC In Vivo Gene Modification as a Method of Generating CAR-T Cells Webinar that will address alternative strategies to deliver chimeric #antigen receptors (#CARs) to modify T #cells in #vivo. Learn more & save your spot: sitcancer.org/DeepDive

Excited to share our Cancer Cell @CellPressNews article on the discovery of the IL-15 Receptor "Regulome". A technical tour-de-force from the Immunology, computational biology & functional genomics teams @oNKo_innate @MonashBDI

We’re honored to have @KDrazan, MD, Co-founder, CEO, and Chairman of the Board, recognized as a winner in the EY Entrepreneur Of The Year® 2025 Bay Area program. go.ey.com/4kI4eJI #EOYUS #EOYBAYAREA

Ever wondered about IL-12 toxicity? Here we build off Garcia labs and @synthekine to de-couple immune parameters and toxicity associated with IL-12 agonism: Cell Reports cell.com/cell-reports/f…

As a son of a poor, Mexican immigrant family, I’m humbled to finish my vascular surgery training at @NMCardioVasc & start my job as Assistant Professor of Surgery at @Stanford @StanfordVasc & provide care to a diverse patient population at Santa Clara Valley Medical Center!

Congrats to #StanDOM's Nathan Lo (@NathanLo3579) on being named a @theNAMedicine Emerging Leader! As a 2025-2028 Scholar, he'll join top early-career minds advancing health & medicine nationwide. stan.md/3ZYh1PV

Targeting immune hubs to advance cancer immunotherapy | Science Translational Medicine ⁦@GladstoneInst⁩ ⁦@parkerici⁩ ⁦@UCSFMedicine⁩ science.org/doi/10.1126/sc…

PanKbase #ADA2025 spotlight: PI @annagloyn presents Sun. the 22nd at 2pm CDT. Session: Genetic Regulation of Beta-Cell Mass and Function in Humans: Lessons from GWAS and Rare Genetics. Her talk: "Integrating Multiomic Data to Understand Complex Gene Regulatory Networks in Islets"

Tay Lab is looking for a computational postdoc to work on proximity sequencing projects. Our new experimental pipelines extend this method to spatially resolved tissue measurements, intracellular proteins, as well as protein modifications like glycosylation, phosphorylation, etc.

We previously showed that IFNg is required for CAR-T efficacy in solid tumors, but is it always good? Here, we show that IFNg limits CD28 CAR-T cells and that protection from this signal drives greater antitumor activity and durability. Enjoy! science.org/doi/10.1126/sc…

Today - we begin a Legacy, Learning, and Justice Journey with a network of @BWFund grantees, stakeholders, and partners. The #bwfden in action!