ChrisHunter
@KingOfPathogens
Scottish Cytokine Immunoparasitologist @KingOfPathogens.bsky.social
See bronchial Beaker cell from @IHeartHisto - I will provide an appropriate bounty for the best (or any) Gritty cell.
For those with an interest in enteric infections (or if you have had Beaver Fever) - this commentary summarizes recent studies on the potential benefits of Giardia. Public offering of shares in ParasitesAreUs to come.... rdcu.be/ew8nk
Subscribe on the PATH website to get details of upcoming general information Zooms ahead of the letter of intent deadline.
BWF PATH Letter of Intent Deadline is coming soon! Just think of the possibilities!
New in @SciImmunology! @EmilyAunins, Dr. Anthony Phan, and their colleagues in the @WeissmanLab and Hunter Lab (@KingOfPathogens) used lipid nanoparticles encoding IL-12 to boost CD8 T cell responses to mRNA vaccines. 📃 bit.ly/3G24jZL 🎧 bit.ly/4n7qA96
What a week: I was lucky enough to get an ERC Advanced Grant, a Wellcome Trust Discovery award, and my fab colleagues at Inflammazoom nominated me for this BSI award. Thank you so much x.com/britsocimm/sta…
Congratulations to the winner of the 2025 BSI Outstanding Leadership Award, sponsored by @CEIjournal… Professor Clare Bryant, @ClareBryant13 !
Improving T-cell responses to vaccines ft. @emilyaunins (@CAMBUPenn), @KingOfPathogens, Anthony Phan (@PennVet), Susan Domchek (@PennCancer), @WeissmanLab (@PennMedicine), @MgAlameh (@PennPathLabMed) & @SCOTTeHENSLEY (@PennMicro) @SciImmunology tinyurl.com/2p8xztbz
ITCH revolutionized veterinary medicine and what is considered a BLOCKBUSTER drug and a major indication. Apoquel (JAK inhibitor) was approved in 2013 for canines and literally sold like hotcakes. Itch in dogs is now a $multiBILLION dollar market: 🧵
Drawing attention to our senior immunology student Mark Maynes who published his MRI and spectral flow cytometry methods to measure neuroinflammation and neurodegeneration in dementia models. Nice job Mark! @markmaynes_ sciencedirect.com/science/articl…
Get your proposal together for BWF PATH's 2026 awards! Letter of Intent deadline is July 17, 2025
Now open - LOIs for the Investigators in the Pathogenesis of Infectious Disease (PATH) program. Deadline is July 17 @ 3pm ET. More information here: buff.ly/iSu3v60 #bwfpath #GrantOpportunity
Ever wondered about IL-12 toxicity? Here we build off Garcia labs and @synthekine to de-couple immune parameters and toxicity associated with IL-12 agonism: Cell Reports cell.com/cell-reports/f…
Sharing Dr Marina Seady’s comprehensive review published in Trends in Neuroscience regarding CD8 T cell mediated blood-brain barrier disruption. Great job Marina! @marinaseady lnkd.in/gPZsTA4j
Microbial Pathogenesis Peeps - New Investigators - this one is for you! Easy first round one pager. Break out your imagination and think of those high risk-reward projects and risks you want to take.... bwfund.org/funding-opport…
We previously showed that IFNg is required for CAR-T efficacy in solid tumors, but is it always good? Here, we show that IFNg limits CD28 CAR-T cells and that protection from this signal drives greater antitumor activity and durability. Enjoy! science.org/doi/10.1126/sc…
Ohh - so cool. For lovers of THE interferon.
We previously showed that IFNg is required for CAR-T efficacy in solid tumors, but is it always good? Here, we show that IFNg limits CD28 CAR-T cells and that protection from this signal drives greater antitumor activity and durability. Enjoy! science.org/doi/10.1126/sc…
For the immunologists still on X science.org/doi/10.1126/sc…
25 years ago, I came to Stanford on a J1 visa and worked so hard to be worthy of that privilege. Today, I lead Immunology at Mount Sinai and I am the one who feel privileged when brilliant international students chose to join us.
Incredible! Over the past 2 months, 5 independent manuscripts — from @TheColonnaLab, Dan Littman, @gardnerlabUCSF and @themis_brown, and our own (now in @Nature nature.com/articles/s4158…), reports that the dietary pTreg program is initiated by RORγt⁺ antigen-presenting cells. /1