Sanjay Srivatsan
@SRsrivatsan
Assistant Professor at @fredhutch. Previously, @UWproteindesign, @uwgenome, and @NIAIDNews. Building sequencing tools to explore biology.
Today out in @biorxivpreprint we present SCOPE. An optics-free, self-registering array of DNA encoded beads for spatial genomics. This was work led by the intrepid duo of Hanna Liao and Sanjay Kottapalli, with @JShendure's lab. biorxiv.org/content/10.110…
Excited to share our work with @julie_trolle and @JefBoeke We developed a 'shotgun' method to screen millions of synthetic metabolic pathways to enable mammalian cells to grow without two essential nutrients for the first time in >500 million years! biorxiv.org/content/10.110…
E11 Bio is excited to share a major step towards brain mapping at 100x lower cost, making whole-brain connectomics at human & mouse scale feasible (🧠→🔬→💻). Critical for curing brain disorders, building human-like AI systems, and even simulating human brains. 1/N 🧵
A team of researchers reached into the genome of a seven-month-old baby with a base editing therapy targeted specifically to repair his unique mutation. Now nine months old, baby KJ, as he is known, appears healthy nature.com/articles/s4158… rdcu.be/evbZK
Please RT🔁 I will be hosting this Synthetic Biology Workshop at @WPI_PRIMe in Osaka on July 15. Great lineup of speakers: @_mattrich, @Lab_Nagai, @CarldeBoerPhD, @nikashakiba, @kenjikamimoto68, @tToshimichiY. The event will be followed by a networking session🥸
Procrastinators unite! 4 hours left for Flux applications!
"The game is far more brutal if you're young. A young scientist with their own lab who sets their own research direction is unheard of." Steer your own ship with Flux. Applications due at midnight tonight.
Hiring alert! @SRsrivatsan @fredhutch and I @HHMIJanelia are looking for a joint postdoc to combine single-cell omics and ex utero embryogenesis. Please retweet! If you are interested, DM us or send an email to [email protected] ; [email protected]
New preprint! We carried out the largest complementation and inhibition study for diverse homologs in a single protein family (DHFR) to date. Highlights thread follows... 1/n 🧵
Exploring Antibiotic Resistance in Diverse Homologs of the Dihydrofolate Reductase Protein Family through Broad Mutational Scanning biorxiv.org/cgi/content/sh… #biorxiv_synbio
Our annual DSA scientific retreat is just around the corner! We will be celebrating our 2024 DSA winners: @zz_zhaozhang, @WangLabUIUC, @SRsrivatsan, and @crcadwell. If you would like to become a DSA awardee, the application portal is now open! bit.ly/3uJMmJo
Since we announced the FutureHouse AI for Science Fellowship, we've had a bunch more amazing professors sign on as potential co-advisors: Sergey Ovchinnikov (MIT) Ellen Zhong (Princeton University) Patrick Hsu (UC Berkeley/Arc Institute) Pratyush Tiwary (University of Maryland)…
We need more programs like this one (@FutureHouseSF) to bring new ideas into the biological sciences. As mentioned in the fellowship link, our lab is excited to co-advise fellows who want to solve the world’s biggest problems with cutting edge tools. DM me if you want to talk
FutureHouse is launching an independent postdoctoral fellowship program for exceptional researchers who want to apply our automated science tools to specific problems in biology and biochemistry, in collaboration with world-leading academic labs. --$125,000 annual stipend.…
Grateful for the support of the Sontag Foundation, we’re excited to do this important work!
The Sontag Foundation is proud to announce that Sanjay Srivatsan, Ph.D. from @fredhutch is our second DSA recipient of 2024! His funded project is titled 'Reconstructing Glioblastoma’s Cellular Origins Using Single Cell Genome Sequencing.' #DSA2024 #DSAgrantee @SRsrivatsan
New work by Mia Yang's lab reports evidence of prevalent aneuploidies in human trophoblast stem cells and suggests that chromosomal instability may be a normal feature of placental development. biorxiv.org/content/10.110…
I am ***absurdly*** excited to announce the launch of a new funding opportunity through Experiment dot com!!! You have one month to pitch something wonderful in the realm of plant biology/biotech research and education. $10,000 max grant. PLEASE RT!!! 1/3 experiment.com/programs/plants
Please consider working with us! We have a wonderful growing team and exciting roadmap ahead.
@BrianHie and I also have a joint postdoc position open (for ML and synthetic biology projects), as well as roles in our Technology Centers. Several posted (and unposted jobs!), check out arcinstitute.org/jobs to learn more or just contact us anyway
🧵In new work, we report a systematic engineering roadmap to optimize large serine recombinases (LSRs) for direct, site-specific insertion into the human genome 🧬. We achieved over 50% insertion efficiency and 97% genome-wide specificity, a 10X improvement over our previous work
Great faculty position in VIDD @Fredhutch open-strong support from the Bezos family included! Please apply and/or RT!
Join us in accelerating groundbreaking discoveries in #infectiousdiseases and #immunology! Fred Hutch is seeking a scientific leader for the Bezos Family Distinguished Scholar in Viruses and Vaccines faculty position. Learn more and apply: bit.ly/488PkH4
Hey folks, I know most deadlines are fast approaching, but I am applying for assistant professor positions this cycle, and I would appreciate recommendations for open positions! My research plan is focused on MGEs, genome engineering, and applying AI to biological discovery.
New synthetic biology / gene regulation lab opening in Zurich! We’re studying how to control cell state transitions – for example, making diseased cells healthy or creating new cellular functions – using systematic perturbations, single-cell genomics and machine learning. 🧵1/4
Absolutely nuts!!! History made! Congrats to your whole awesome team!
Mechazilla has caught the Super Heavy booster!
♥️♥️♥️
We recently spent a day in the lab with 2024 @NobelPrize winner and HHMI Investigator David Baker, where he discussed his groundbreaking work, the importance of basic science, and his passion for mentorship #NobelPrize