Alejandro Aguilera Castrejon

Thanks to MIT Technology Review for selecting me as one of the 35 innovators under 35 for 2024!

Enhancers, how do they work (in vivo)? To find out, we mutagenized 7 human enhancers comprehensively in 12bp blocks and scored for activity in developing mouse embryos. rdcu.be/erD22 @Nature #mutagenesis #noncoding #enhancers

Thrilled to announce that we are looking for a Research Technician/Assistant to join our lab @IMBA. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab! I’m thankful for any retweet! imba.onlyfy.jobs/job/l6u2m980

In our interview with Jennifer Lippincott-Schwartz @JLS_Lab, we discuss her research career, her advice on building collaborations and learn why she is looking forward to #biologists100. Jennifer will be speaking in our emerging technologies session. journals.biologists.com/jcs/article/13…

It was a privilege to be invited by Celeste Nelson to talk about our work princeton at @Princeton. I was excited to see Nobel Laureate Eric Wieschaus among the audience, one of the heroes of #devbio

Princeton's new Bioengineering Institute @omenndarlingbio is hiring! New building opening this Fall, & Princeton is awesome place to live & do amazing research at intersection of engineering & life sciences. **Please spread the word*** bioengineering.princeton.edu/join/open.

Still can't believe we got onto the cover of Science! Across 11 reserves and 7 years, we found that dehorning rhinos achieved large reductions in poaching. But it's not a magic bullet (read why) Full article: science.org/doi/10.1126/sc… Popular version: dailymaverick.co.za/article/2025-0…

Headline here nature.com/articles/d4158… should be “Iron deficiency in pregnant mice causes (SOME) XY embryos to develop with female characteristics. Interesting how 4/5% becomes a general statement. Result clearly says iron deficiency alone DOES NOT cause the phenotypic change.

🥳 Happy #DNADay! 🧬 What better way to celebrate than with cycleHCR: one of our newest tools, developed by the Liu Lab, that uses a novel DNA barcode system to track hundreds of RNA & protein molecules in single cells within thick biological samples ➡️ janelia.org/news/new-metho…

A new tissue expansion method developed by the Wang (@mengwang939) & Tillberg (@TillbergPaul) labs & the @LingjunLi2 lab @UWMadison enables scientists to use mass spec imaging to simultaneously detect 100s of molecules in single cells in intact tissues➡️ janelia.org/news/new-techn…

#hiring! come join @Eric_Betzig and the rest of an amazing team at the Advanced BioImaging Center at UC Berkeley to help us build the #CellObservatory! 1/2 aprecruit.berkeley.edu/JPF04858

Are you a #biologist looking to learn more about cell surface molecules? Apply today to attend a cross-disciplinary conference on the #biology and engineering of the cell surface at @HHMIJanelia (October 5-8). This @janeliaconf will: 🧪 Connect tool developers with biologists…

In this Review, @BernaSozen_ , Patrick Tam and @martinperaJAX summarize how recent studies of embryo models have advanced our understanding of cell state transitions of the pluripotent human epiblast and highlights some key remaining questions: doi.org/10.1242/dev.20…

Construction of an atlas of transcription factor binding during mouse development identifies popular regulatory regions Read this Techniques & Resources Article by @AnnaNordin96, @GianlucaZamba, @MattEJonasson, @ppagella86 Claudio Cantù & co.: doi.org/10.1242/dev.20…

🔬 The Liu Lab needed to image hundreds of RNA molecules in thick tissues but there weren’t any tools that were up to the task. 🧪 So, they built their own tool – and are now working to make it available to labs worldwide. #openscience janelia.org/news/new-metho…

The Department of Cellular Biology and Physiology at the Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), is seeking a member for its research staff!! See details👇 biomedicas.unam.mx/wp-content/pdf… PLEASE, SHARE!!!

Deadline for abstract submission & registration approaching The time is now!!!! meetings.embo.org/event/25-dev-t…

We’re living through pretty unusual times, but we’re excited to share good news! Our CRISPRa-programmed #embryo model paper is out! Thanks to our amazing group @glodewijk_sci @sayakakozuki and collaborators. I hope the community finds this model useful for new discoveries #CRISPR

📢 #AI & #CellularPhysiology researchers 👉 join us March 30-April 1 for a free livestream of our conference examining the intersection of these fields. Topics include AI-driven insights into genomes, overcoming dataset challenges & more. 🔗Register: janelia.news/register