Julia Joung

Thrilled to share my primary PhD work: a Transcription Factor Atlas for understanding gene regulation and cell engineering @CellCellPress. We created a comprehensive TF ORF library and applied it to profile resulting expression changes. A thread 1/X sciencedirect.com/science/articl…

SPIDR enables multiplexed mapping of RNA-protein interactions and uncovers a mechanism for selective translational suppression upon cell stress: Cell cell.com/cell/fulltext/…

Thrilled to be launching @terrainbiosci today! Revolutionizing RNA medicines with our AI-powered design & manufacturing platform Helping biotechs get better mRNA candidates to patients, faster 🧬 #biotech #RNAmedicine w/ @jgooten @pdhsu Chetan and many others (awesome team!)

Excited to announce that this work is now live as a first release article @ScienceMagazine So grateful for this fantatic team and to see this work in wild! science.org/doi/10.1126/sc…

Why do some genetic mutations devastate specific tissues while sparing others? We explore this question in GGC repeat disorders, revealing a mechanism linking protein aggregation to tRNA splicing failure in the brain. 🧵 on our new paper in Science: 🔗 science.org/doi/10.1126/sc…

Just published in Nature (June 2025), Andersen et al. (@EAChiocca, Reardon, @QuintanaLabHMS) developed a novel viral barcode interaction-tracing (RABID-seq) platform, uncovering previously unknown immunosuppressive interactions between astrocytes and glioblastoma (GBM) cells.…

Repeat-element RNAs integrate a neuronal growth circuit: Cell cell.com/cell/fulltext/…

PAPER ALERT! Excited to share my PhD work in the lab of @larsplus @CRGenomica. We screened minimalistic synthetic enhancers throughout myeloid differentiation. We uncovered widespread dual activator-repressor functions for individual TFs and TF pairs tinyurl.com/4z3rntyz (1/n)

Stem cell therapy for Parkinson’s disease has entered a new era. Two @Nature studies demonstrate that pluripotent stem cell–derived dopamine neurons can survive, restore function, and potentially change the treatment paradigm for this neurodegenerative disease.

Inserting large, scarless DNA sequences is a major hurdle for gene therapy. We explored if site-specific retrotransposons, natural genome editors found across the tree of life, could be engineered for this task. Excited to share STITCHR in @Nature with @jgooten!

This is the most important paper in the circadian field in over a decade. A completely new clock component that is evolutionarily conserved. @Eric_E_Zhang @susanksgolden @ @SRBR_Outreach rdcu.be/efxV8

The massive changes in US research brought about by the new administration of President Donald Trump are causing many scientists in the country to rethink their lives and careers go.nature.com/4cbUXX0

The latest from @GladstoneInst of Cardiovascular Research and @ucsf: Isha Jain's lab, with an outstanding discovery of a small molecule that mimics hypoxia, to treat neurodegenerative diseases. The amazing Sylar Blume, RA in Isha's lab, is first author! cell.com/cell/fulltext/…

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis…

Big #RegenerativeMedicine advance! New study demonstrates the use of iPSC-heart muscle to treat a patient with heart failure. The patches successfully engrafted, contributing to heart repair. Patient survived 3 months before receiving a heart transplant nature.com/articles/s4158…

Super excited to share our new study from the @JD_Buenrostro Lab in @Nature! We developed a computational method for tracking transcription factor and nucleosome binding using single-cell ATAC-seq and deep learning. Paper: nature.com/articles/s4158…

Could one envision a synthetic receptor technology that is fully programmable, able to detect diverse extracellular antigens – both soluble and cell-attached – and convert that recognition into a wide range of intracellular responses, from transgene expression and real-time…

Delighted to share our #NightScience tale: "A tetramer of BCL11A is required for stable protein production & fetal hemoglobin silencing," in @ScienceMagazine. Co-led by Zheng Ge, Yin Maolu, & me, here’s a tweetorial about our puzzle-solving adventure! 1/7 tinyurl.com/2tpaaua3

I’m thrilled to share this story from @Mendell_lab and Jan Erzberger labs, led by postdoc extraordinaire Xiaoqiang Zhu! We showed that in addition to their canonical decoding function, tRNAs play a key role in regulating mRNA stability during translation. science.org/doi/10.1126/sc…

EVOLVEpro, our general AI model for protein engineering, is now out in Science! We show the ability to design and evolve dozens of unique proteins to have up to 500 times more activity or function using a combination of LLMs and regression models. 🧵👇 science.org/doi/10.1126/sc…