Raghu Chivukula, MD PhD 🫁🧬🧠

@chivukula_raghu

physician-scientist @harvardmed @MassGeneralNews & @CGM_MGH | dadx2 | porschephile | via @JohnsHopkins @HopkinsMedicine @MGHMedicine @HarvardPulm @WhiteheadInst

Boston & Camberville, MA

Joined January 2020

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Raghu Chivukula, MD PhD 🫁🧬🧠@chivukula_raghu · Jul 21

Why do some genetic mutations devastate specific tissues while sparing others? We explore this question in GGC repeat disorders, revealing a mechanism linking protein aggregation to tRNA splicing failure in the brain. 🧵 on our new paper in Science: 🔗 science.org/doi/10.1126/sc…

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Raghu Chivukula, MD PhD 🫁🧬🧠 Retweeted

Cell@CellCellPress · 12 h

Now online! SPIDR enables multiplexed mapping of RNA-protein interactions and uncovers a mechanism for selective translational suppression upon cell stress dlvr.it/TM4dlf

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Hao Zhu Lab@Zhu_Lab · Jul 12

Intro to 2 new studies from my lab on somatic mutations in liver disease. 1st is about a mutated gene that leads to improved clone fitness and organismal health (CIDEB). The 2nd is about a mutated gene that leads to improved clone fitness but worse overall health (TBX3). 1/8

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Michael Pacold@MichaelPacold · Jul 9

Just published: nature.com/articles/s4158… Coenzyme Q10 (CoQ10) is critical for mitochondrial function and for controlling reactive oxygen species damage to biological membranes. Because CoQ10 is poorly bioavailable, new approaches are needed to promote CoQ10 synthesis. In our…

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Raghu Chivukula, MD PhD 🫁🧬🧠@chivukula_raghu · Jul 9

This is a really remarkable scientific and clinical story — just beautiful, rigorous work with direct relevance to human disease. Congratulations @MichaelPacold and team!

NNYU Grossman School of Medicine@nyugrossman · Jul 9

Discover how @nyugrossman’s Dr. Michael E. Pacold turned a basic question about oxygen into a potential cure for a rare pediatric disease. #BehindTheBreakthrough Watch the latest episode: bit.ly/45UNk6e Head to nature for the full study: go.nature.com/45W5W5R

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Joshua Mendell@Mendell_lab · Jul 2

I am pleased to present our latest pre-print describing our identification of the long-sought triggers for target-directed microRNA degradation (TDMD) of miR-322 and miR-503, led by @ColletteLavigne and @Jaeil__Han. Read on for more info!👇 biorxiv.org/content/10.110…

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Raghu Chivukula, MD PhD 🫁🧬🧠@chivukula_raghu · Jun 27

Legend

RRajshri (Mainthia) Gartland@RMGartlandMD · Jun 26

Truly no one more deserving of the @MGHSurgery 2025 faculty mentor award

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Raghu Chivukula, MD PhD 🫁🧬🧠 Retweeted

Marty Taylor, MD PhD@DrMartyTaylor · Jun 14

Excited to share I've been selected as the 2025 Rita Allen Milton E. Cassel Scholar. This award honors the memory of a longtime President of the Rita Allen Foundation. I am very grateful to Foundation for the support and recognition of our work and ideas. ritaallen.org/stories/2025-s…

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