Julia Bauman
@JuliaBauman2
PhD student at @Stanford Genetics in @LarsMSteinmetz lab | Prev @broadinstitute | Explaining cool biotech to the world here and @ 60_SecondScience on TikTok
Lab scientists are now resorting to "Go fund me" like campaigns to keep their labs afloat (and not fire personnel). Just awful (but do consider helping them out!).
As of today @Columbia has not received ANY of the terminated funding and many non-competitive renewal of federal grants. Therefore, last week the university starting laying off postdocs. If you care about PANDAS research please support my postdoc joinus.cuimc.columbia.edu/index.cfm?fuse…
A study in Cell reports the first high-resolution structures of measles virus polymerase complex (the molecular “machine” that builds viruses) alone and with inhibitors. The researchers used these structures to show that one of the inhibitors also works against Nipah virus!…
My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15
Now that the budget bill has passed Congress, we can see what the projections look like for deficits, government debt, and debt service expenses. In brief, the bill is expected to lead to spending of about $7 trillion a year with inflows of about $5 trillion a year, so the debt,…
CASP is getting cut by NIH... 😢 (Anyone with extra funds wanna help support perhaps the most important competition of the century?) science.org/content/articl…
So you want to change transgene expression: just change your promoter, right? Changing the promoter increases RNA and thus protein levels. What more could be happening? [1/n] Well, promoters don’t just set RNA levels; they uniquely transform how RNAs are transmitted into protein…
Prevention beats cure, which is why it's so exciting that Lenacapavir, a twice-yearly HIV preventative, just got approved for the first time (by the FDA) Why is it such a big deal? When trialled (in women in South Africa and Uganda) there were 0 HIV infections 🧵
New in @Nature: A brain-computer interface that turns thoughts into voice in just 10 milliseconds. For the first time, someone who lost their speech can ask questions, emphasise words, and sing - all through brain signals alone. Here's how they did it 🧵
People—teachers, students, parents—have been complaining for a century that memorization is pointless when ”you can just look it up“. This complaint predates AI, it predates Google, it predates this internet. But it’s wrong. Here’s Pauling on why he gave closed notes exams:
NEW POST on AI, learning and why knowing stuff still matters. Link in reply ⬇️
Interesting piece on a nasty common disease More endometriosis research needed!
Endometriosis is an incredibly interesting disease 5k words, 23 minutes reading time covering one of the strangest conditions ive ever heard about link: owlposting.com/p/endometriosi… very grateful to @shilpap_ for initial inspiration for this piece + reviewing it!!
I had been craving a real-world exploration of antimemes since reading TINAD @nayafia’s book really delivers, very enjoyable read
I wrote a new book! It's called ANTIMEMETICS: Why Some Ideas Resist Spreading, and it's about ideas that don't want to be shared or remembered, despite their importance. Now available for pre-order: darkforest.metalabel.com/antimemetics
After over a year of incubating, I’m excited to share a new project inspired by a ~decade of in vivo drug discovery experience 🧬 Artemis is a Focused Research Organization (FRO) to establish alternative, naturally physiologically human-like animal species for complex disease…
The peer-reviewed version of expansion in situ genome sequencing is now out in Science! The news is bittersweet – when we first revealed this last September, I never guessed it would be my final paper in academia, but a lot has changed. A few parting thoughts:
I remember getting the advice that it doesn’t really matter what you focus your graduate work on as long as you find it interesting This analysis suggests otherwise - if you care about impact, choose a research area to commit to for the long haul!
The further a scientist moves away from the topic of their previous work, the fewer citations their new work will receive, according to an analysis of millions of scientific papers and patents published in @Nature. go.nature.com/3HdyflX
This is an incredible progress story An aggressive type of cancer (Philadelphia chromosome–positive acute lymphoblastic leukemia) used to carry a dismal prognosis, with 50% of patients dying in a year New therapies have transformed it to a cancer that most people are cured of