Jason C.L. Tong
@JasonCLTong
DPhil candidate @UniofOxford specialising in islets, incretins, and diabetes. Likes microscopes 🔬 🇦🇺🇭🇰
Nice one @daveyboyhod !
Dr. David Hodson (@daveyboyhod) and team show that GLP1R is enriched as nanodomains on beta cell membranes that contact alpha cells, in keeping with increased single-molecule transcript expression. 💡 Learn more: bit.ly/451mubz
Dr. David Hodson (@daveyboyhod) and team show that GLP1R is enriched as nanodomains on beta cell membranes that contact alpha cells, in keeping with increased single-molecule transcript expression. 💡 Learn more: bit.ly/451mubz
This is a *pretty amazing* paper--really fascinating implications for those who wish the field would finally begin to look into #cellbio cell.com/cell-metabolis…
A regulated pathway through which glucagon modulates insulin release via alpha to beta cell communication and control of GLP-1R internalization and beta cell Ca2+ responses to high glucose @Cell_Metabolism @daveyboyhod #islets cell.com/cell-metabolis…
Great read!!
New! Online now: Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication dlvr.it/TLvwgF
Tong et al. show that beta cells adjacent to alpha cells are equipped as glucagon sensors by virtue of glucagon-like peptide-1 receptor enrichment and disproportionately contribute to alpha cell regulation of beta cell function. cell.com/cell-metabolis…
膵α細胞はグルカゴン放出を介してβ細胞の機能をパラクライン的に調節しますが、分子機構は不明です。α細胞に隣接するβ細胞がGLP1Rの高発現によってグルカゴンセンサーとして特別に適応して血糖値の上昇に最初に反応していることを示した論文がCell Metab誌に発表されました。 cell.com/cell-metabolis…
Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication: Cell Metabolism cell.com/cell-metabolis…
Cell Talk Gets Smarter with GLP-1! Localized GLP-1 receptor pre-internalization enhances alpha-to-beta cell communication unlocking new insights in glucose control! #GLP1 #PancreaticCells #AlphaToBeta #CellCommunication #Diabetes #Endocrinology #Insulin cell.com/cell-metabolis…
Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication: Cell Metabolism cell.com/cell-metabolis…
Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication. cell.com/cell-metabolis…
New! Online now: Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication dlvr.it/TLvwgF
Very pleased to share my first-author paper, now published online in @Cell_Metabolism featuring my DPhil work with @daveyboyhod. We used advanced imaging approaches to reveal the mechanisms underlying islet α-cell to β-cell communication via GLP1R. sciencedirect.com/science/articl…
It was my honour to have been nominated by the Australian High Commission to attend the King’s Garden Party at Buckingham Palace as a representative of Australia, in recognition of my work. Meeting Their Majesties up close was a particular treat!
