Islet Biology Lab - UMH
@isletbiologylab
We're interested in islet cell function and survival in #type1diabetes. Headed by @lmarroqui and @rsdossantos13. @UnibadUMH/@IDiBE_UMH/@ciberdem/@GVAfisabio
Excited to share this fantastic @T1D_TrialNet paper by @erinltempleman @EmKSims Lauric Ferrat, Nick Thomas @cevansmo @catespeake and colleagues @UniofExeter @ExeterMed #ExeterDiabetes @IUSweetTweets diabetesjournals.org/care/article-a…
Auddino et al. discuss the potential link between cellular stresses and isomiR biogenesis, and how this association could improve our knowledge of islet inflammation and dysfunction. cell.com/trends/endocri…
Nanaware et al. used mass spectrometry to identify native and post-translationally modified self-peptides presented by MHC proteins from human cadaveric islet samples treated in vitro with cytokines to identify epitopes in an inflamed pancreas. cell.com/cell-reports/f…
RESEARCH | @MatthiasTschop, @TimoMueller_IDO et al (@HelmholtzMunich) Part 2: This study and a co-pub delve into how both #GIPreceptor #agonists and #antagonists trigger weight loss through different mechanisms. nature.com/articles/s4225…
P.S. we would be remiss if we did not also thank the amazing reviewers and editor who made our work better and more complete. As well as @cevansmo for the lovely commentary on our work! nature.com/articles/s4225…
Type 2 diabetes is often considered a protein misfolding disease. But where are these toxic proteins found? 🤔 🚨In new work out today in @NatMetabolism, we show that mitochondrial protein misfolding (yes mitos🤯) leads to beta cell damage in T2D. 🚨 nature.com/articles/s4225… 1/n
Degroote et al. provide evidence that continuous administration of verapamil combined with a short course of low-dose rabbit-anti-mouse ATG significantly improves glucose control in recent-onset diabetic NOD mice, outperforming either treatment alone. link.springer.com/article/10.100…
📣 Lanzamos un nuevo #calendario de #convocatorias con información clara, estructuradas y actualizada sobre las principales convocatorias de ayudas previstas para la segunda mitad del 2025. 👉 aei.gob.es/convocatorias/… 📍 Novedades 🔹 Listado de las convocatorias cuya apertura…
Fundación DiabetesCERO lanza la primera convocatoria internacional «Frontiers in T1D Cure 2025», una iniciativa destinada a financiar proyectos innovadores de investigación biomédica centrados en encontrar una cura para la #diabetestipo1. Se concederán dos becas de 100.000 €…
Coming Soon: Frontiers in T1D Cure 2025 2 grants of up to €100,000 to fund innovative research to cure type 1 diabetes. Applications open soon. Stay tuned & share! #Type1Diabetes #ResearchFunding #DiabetesCERO
El próximo viernes, 25 de julio, a partir de las 12:00 en la Sala Van Humboldt del edificio Torregaitán, tendrá lugar el seminario «Brainstem circuits regulating ingestive behaviours». La sesión correrá a cargo de el Dr. Pablo B. Martínez de Morentin de la Universidad de Leeds
🫵Preinscripción abierta hasta cubrir plazas🏟️: 🖱️lnkd.in/eh67k_N ▶️Más información sobre el @mbiotingUMH: 🖱️lnkd.in/dzjZEuyQ 💡Una formación diseñada para afrontar los retos científicos y tecnológicos del futuro 🎯
3⃣ Capacitación para diseñar intervenciones industriales, terapéuticas o preventivas eficaces. 4⃣ Habilidades para la divulgación científica, orientadas a poner en valor el impacto social de la ciencia.
🚨 ¡¡¡RECORDAD, MAÑANA ÚLTIMO DÍA para la preinscripción al @mbiotingUMH!!! 🗓️Este programa combina la experiencia de dos centros de referencia de la @UniversidadMH, el @IB_UMH e @IDiBE_UMH, con la participación de grupos de investigación 🚀punteros en sus disciplinas 🔬🦠 🧵
Findings by Steck et al. increase our understanding of #type1diabetes development and support incorporating the #T1D genetic risk score 2 to enhance the prediction of progression through the preclinical stages of T1D. doi.org/10.1210/clinem…
If you're eligible, don't miss this great Scientists Training Course!!!
🔔 Reminder: Applications for our Scientists Training Course 2025, at @idibaps, are open! Unique opportunity for early career scientists to advance skills & career in #diabetes #research! 📅 10 - 14 Nov '25📍Barcelona More 👉easd.org/education/meet… Supported by @LillyDiabetesIn
🎓🔬 ¡Últimos días para preinscribirte en el Máster en Biotecnología y Bioingeniería de la UMH - @mbiotingUMH! 📅 El plazo acaba el 17 de julio de 2025 📌 ¡Últimas plazas disponibles! Toda la info en: …er-biotecnologia-bioingenieria.umh.es Preinscripción aquí: universite.umh.es/preins_postgra…
Tong et al. show that beta cells adjacent to alpha cells are equipped as glucagon sensors by virtue of glucagon-like peptide-1 receptor enrichment and disproportionately contribute to alpha cell regulation of beta cell function. cell.com/cell-metabolis…
La Fundación @diabetes_CERO lanza la convocatoria internacional 'Frontiers in T1D Cure 2025', una iniciativa para impulsar proyectos de #diabetes tipo 1. Se otorgarán dos ayudas de 100.000 € a investigadores consolidados con enfoque traslacional lc.cx/7gr0EV
Join us TOMORROW for the 1st CIBER-DZD joint meeting! We're diving into the latest developments on incretin agonists and their role in metabolic diseases, featuring speakers from Spain and Germany. 🗓️ July 15 🕞 15:30–16:30 (CEST) 🔗Registration: tinyurl.com/f8uzk2w2

Excited to present this today at #ENDO2025 with Drs. Dirk Homann and Al Powers who organized. Swing by and join the discussion.
Michels et al integrate and summarize information about the pathogenesis of T1D, highlight gaps in current knowledge, and propose future activities that may lead to additional approaches to treat the underlying autoimmunity and β-cell defects in #diabetes. doi.org/10.1210/clinem…