Igor Ulitsky ๐
@IgorUlitsky
Associate Professor @WeizmannScience . lncRNAs, RNA biology, RNA therapeutics, gene regulation, all wet+dry. Father of 4. Not much time for anything else.
Website update: "Guide for following the scientific literature" that I first in ~2008, now updated for 2018 - including Twitter, BioRxiv, shoutout to @RNApreprints and more. Mostly useful for early career scientists, so distribute! weizmann.ac.il/Biological_Regโฆ
Many proteins bind RNA, yet we still donโt know what RNAs most bind because methods map one RBP at a time. In @CellCellPress, with the Jovanovic lab, we describe SPIDR โ a method for mapping the RNA binding sites of dozens of RBPs in a single experiment. sciencedirect.com/science/articlโฆ
Our preprint describing the Range Extender element, which is required and sufficient for long-range enhancer activation at the Shh locus, is out in @Nature. nature.com/articles/s4158โฆ
How do enhancers work over distances that sometimes exceed megabases? Excited to share our work led by @gracecbower where we uncover a unique sequence signature globally associated with long-range enhancer-promoter interactions in developing limb buds: biorxiv.org/content/10.110โฆ 1/
We are not our government. Support Israelis, help us oppose our government, and help us end the war in Gaza
๐ฅืืืืืง ืืจื ืขืืื ืื, ืื ืฉื ืืฉืจืืืื ืฉืฉืืืฉ ืืจืืฉ ืืกืื ืื ืื ืฉืื ืืืืื, ืืืืจ ืืื ืืงืื ืฉื ืจืื ืืืฉืจืืืื: ืืคืฉืจ ืืชืืื ืืืืื ืช ืืฉืจืื ืืืืชื ืื ืื ืชื ืืื. ืืืืืื. @thehonestlypod with @BariWeiss
Imagine what would happen if they both cut unnecessary meetings and kept working for 5 days a week? Biggest trial of four-day work week finds workers are happier and feel just as productive nature.com/articles/d4158โฆ
Selecting all images with traffic lights
What makes us human
Dear friends, The vast majority of Israelis do not support the ultra-radical, fascist ideology that has taken hold of our political leadership. Our government is acting in direct opposition to the will and values of most of its citizens.
"All you want is all the Palestinians gone... you don't care how many die in the process, do you?" Piers Morgan grills the โGodmotherโ of the Israeli settler movement, Daniella Weiss. Watch the full interview ๐ ๐บ youtu.be/8CwuyoiVNAQ @piersmorgan
How bats developed their wings? ๐ฆ Turns out they reutilize existing gene programs ๐ง Find out more in our paper @NatureEcoEvo in collaboration with @RealFany and @StefanMundlos labs nature.com/articles/s4155โฆ
๐จNew preprint from our labs (STOP lab & Nojima lab @pol2rna)! @kopczynska_m and Chihiro Nakayama have been digging into how chromatin remodeller SETD2 controls the start and end of transcription ๐ (1/5) biorxiv.org/cgi/content/shโฆ
Very excited to share our new work on gastruloids by the incredible @ugcgccacc! We mapped gene expression across 26 individual gastruloids at single-cell resolution and discovered some pretty amazing patterns about how these "mini-embryos" organize themselves.
will be awkward if we solve aging but discover there's a secret 2nd puberty that only hits at 140, lost to the time of noah and abraham
Frightening Rise In Anti-Semitism Blamed On The Jews buff.ly/9mioDUv
East Germany was so good people routinely got shot trying to climb the fence out of it.
In Berlin, a friend told me about a map that was circulating of East and West Germany, illustrating how individual generational wealth was far greater in the Westโa supposed testament to capitalism's superiority. But as my friend pointed out, what the map left out was that inโฆ
Yes, NYT. Whereas much of the world would prefer that Israelis leave themselves surrounded by well-armed enemies determined to do them harm.
Ground-breaking as usual from the Mayr lab
More than 2700 3โฒUTRs are highly conserved. These 3โฒUTRs are essential components in mRNA templates, as their deletion decreases protein activity without changing protein abundance. Highly conserved 3โฒUTRs help the folding of proteins with long IDRs. biorxiv.org/content/10.110โฆ
1/ H3K27me3 mimicry has repeatedly emerged through evolution, but what's the physiological relevance? We show that JARID2 and PALI1 mimic H3K27me3 to antagonise PRC2 in vivo and restrict the spread of Polycomb domains. ๐งต biorxiv.org/content/10.110โฆ
Iggy Pop is one emeritus with a lust for life. Proud to share a nickname!
How weโre rebuilding the Weizmann Institute โ and our hopes for a better future nature.com/articles/d4158โฆ
Novel insights into the silencing of an understudied transposable element - check out our latest preprint by Jakob Schnabl-Baumgartner and colleagues bsky.app/profile/did:plโฆ biorxiv.org/content/10.110โฆ
I am pleased to present our latest pre-print describing our identification of the long-sought triggers for target-directed microRNA degradation (TDMD) of miR-322 and miR-503, led by @ColletteLavigne and @Jaeil__Han. Read on for more info!๐ biorxiv.org/content/10.110โฆ