Laura Formentini
@FormentiniLaura
interested in #mitochondria and #metabolism. 🇮🇹🇪🇸🇺🇸 Professor at UAM university 🐠
The new Mitchell model of OXPHOS in skeletal muscle. rdcu.be/dwqbw @NatMetabolism @FormentiniLab @CBM_CSIC_UAM @UAM_Madrid @FundacionAreces
1/ 🚨 Our new paper is online in @Nature ! As its first author, I’m enthusiastic to finally share it with you all!🎉 🧠 We discovered a mechanistic link between cellular energy metabolism and the control of the need to sleep 💤 👉 nature.com/articles/s4158… @OxfordDPAG 🧵👇
📌 Glucose Metabolism An amazing & versatile substrate! 🍒 🍑 #Biology #Metabolism #Nutrition #MedEd #Science
Lipid synthesis supports membrane growth and organelle biogenesis. Sunyoung Hwang, Eduardo Torres et al. @UMassChan show that synthesis of sphingolipids, mainly long-chain bases, is essential to increasing nuclear membranes during #CellDivision. hubs.la/Q03vNnKP0
Unlike what's in the textbook, neurons and the brain fuel on lipids... nature.com/articles/s4225…
New Online! Key challenges and recommendations for defining organelle membrane contact sites bit.ly/4lnIBP1
🔬 Talk by Laura Formentini (UAM, Spain): What makes our muscles efficient at using fats for energy? It turns out a newly discovered protein team—or metabolon—could hold the key. Here’s what we learned about CoQ, mitochondria, and metabolism. 🧵 #11thConferenceICQ10A
Awesome. Great work, really impressive.
My lab's first paper is out in @Nature. We show that lipoprotein uptake protects tumors from ferroptosis by delivering the lipid antioxidant α-tocopherol. Surprisingly, tumors use sulfated glycosaminoglycans—not canonical receptors—to capture lipoproteins. nature.com/articles/s4158…
The wet, carbon-based matrix of biology behaves like an electrical circuit, slowly fluxing electrons from food ⊖ → ⊕ oxygen Through each step, energy flow meets energy resistance: éR éR is the fire of life, allowing transformation and adaptation Preprint here with the…
Proximity proteomics reveals a mechanism of fatty acid transfer at lipid droplet-mitochondria- endoplasmic reticulum contact sites nature.com/articles/s4146…
We have 2 PhD Positions🔥Join us in Madrid!!
The UNION consortium is excited to announce 17 open #PhD positions! UNION aims to address the challenges of our ageing society. It involves experts from various disciplines (PIs tagged below) and uses cutting-edge technologies. Contact the individual PIs with your EOI
Top Citations 2024: #19🏆✨ @FormentiniLaura (@CBM_CSIC_UAM) and co-authors describe how an ETFDH-driven metabolon supports #OXPHOS efficiency in skeletal #muscle via regulation of coenzyme Q homeostasis 🔄 nature.com/articles/s4225…
We are part of UNION 🩷🌱 -Understanding mitochondrial lipid metabolism in ageing- We will offer 2 PhD position in our Madrid-based lab in 2025 as part of this exciting MSCA-DN. (+ 2 rotations in other outstanding European labs) JOIN US!!! @MSCActions #PhDPosition Please 🔁
#UNION
Thrilled to share our latest work @puigserver_lab in @CellCellPress! Great collaboration with @vivekvivsharma and #LiaoLab, where we show how the combination of #physiology, #cryoem, and #simulations can be implemented as a discovery tool.
New paper by @platorremuro published in @CellCellPress! We combined thermoregulatory physiology, structural and computational approaches to determine the mechanisms of electron transfer and structural basis of respiratory complex adaptation to cold temperatures.
Crosstalk between mitochondria–ER contact sites and the apoptotic machinery as a novel health meter: Trends in Cell Biology cell.com/trends/cell-bi…
A cell videoed through a microscope. The powerhouses/overlords of the cell, mitochondria, are shown in yellow. The nucleus is shown in cyan and actin filaments are shown in magenta. #CellBiology
One of the most beautiful and famous picture of a mitochondrion
Congratulation javi ⭐️🎊, you are the very best!! Well deserved
Grateful to receive the NIH Director’s New Innovator Award #NIHHighRisk Congratulations to all the amazing investigators in this cohort.
Great opportunity ⭐️🔥: Tenure track professorships, Graz 🇦🇹 medunigraz.at/en/job-opening…
This is one of the best reviews about mitochondrial functions. A must read!
As we celebrate mitochondria awareness week, let's remind ourselves that mitochondria are the processor of the cell The 1957 "powerhouse" analogy has expired 😀 Mitochondria process and transform energy, together with hundreds of other signals cell.com/cell-metabolis…