Martin Picard
@MitoPsychoBio
Mitochondrial Psychobiology. Bridging the science of energy and the human experience to create Healing Science. Upcoming book: ENERGY (2026).
To truly decode the brain, we need to transcend disciplines and collaborate openly. Energy efficiency, information processing—these need a systems-level perspective. It's time to bridge the wealth of mapping, omics, and siloed neuroscience data (whether top-down or bottom-up)…
There is strong support for Alzheimer's disease being Type 3 diabetes or "diabetes of the brain" Metabolic dysfunction affects multiple organ systems and their ability to work coherently, at low energetic cost, keeping us in a good health state This video is an example from a…
Breathe for your mitochondria 😀
“The purpose of breathing is to bring oxygen to your cristae.” - @MitoPsychoBio Breathe efficiently and you will improve your body’s ability to move and create energy efficiently.
We need to rethink psychiatry as much as we need to rethink the underlying assumptions of biomedical science
Psychiatry errs because it fails to grasp how incredibly well-designed the human mind really is. Depression, anxiety, even psychosis are signals that carry invaluable information about what’s going wrong in life - yet we idiotically treat them as “symptoms” to be “managed.”
Why do we sleep? What happens in our cells that make us feel the need to go to bed? New study in flies showing that as energy flows with more energy resistance (éR) in our mitochondria--producing "reductive stress"-- the pressure to sleep increases Manipulating mitochondrial…
Why do we sleep? What happens in our cells that make us feel the need to go to bed? New study in flies showing that as energy flows with more energy resistance (éR) in our mitochondria--producing "reductive stress"-- the pressure to sleep increases Manipulating mitochondrial…
A mitochondrion with a snippet sliced off so you can see its inside
Peering into mitochondria - gorgeous life patterns! The parallel infolding are "cristae" where respiration and energy transformation happen The purpose of breathing is to bring oxygen to your cristae
Much of our behaviors are likely driven by the behavior of energy in our mitochondria
Congratulations! Beautiful initiative to address the immense clinical needs and existing gaps in traditional care models Thank you for your good work, Chris
Several new papers on light-biology interactions recently Understanding how patterned energy in it rawest form (light) interacts with crystallized energy (biochemistry and material things) could transform our view of health @msahsorin and others leading the way - thank you!
The theory now is that longer wavelengths of light specifically from sunlight restore membrane potential in your mitochondria, whereas shorter wavelengths of light (such as from LEDs) reduce it. This needs testing, but it’s intriguing & brings together a lot of data.
Wow, fatty acid oxidation in neurons! Time to update the textbooks?!
A study in @NatMetabolism shows that under glucose-depleted conditions, neurons can use fatty acids as an alternative source of energy to support synaptic function. go.nature.com/46ArR2G