Puigserver Lab

A great line-up of speakers for Cell Symposia Multifaceted Mitochondria June 2026 in Glasglow! Check it out and register early: cell-symposia.com/mitochondria-2… @KivancBirsoy @RutterLab @jourdainlab and more! #mitochondria @CellPressNews

A postnatal molecular switch drives activity-dependent maturation of parvalbumin interneurons: Cell cell.com/cell/fulltext/…

#CIBseminars Mechanisms of mitochondrial adaptive respiration Pedro Latorre Muro, Dana-Farber Cancer Institute/Harvard Medical School, Boston, MA (USA) 📆July 17 ⏰15pm Online seminar. Registration required 🔗rediris.zoom.us/meeting/regist…

PGC-1α–mediated phospholipid synthesis plays a pivotal role in BAT thermogenesis in a sex-dependent manner in mice revealing a new therapeutic target for metabolic diseases in postmenopausal women. nature.com/articles/s4146…

Thrilled to share that I’ll be starting my new position as a tenure-track assistant professor at the @OSU Comprehensive Cancer Center on July 1st! And to continue my journey to conquer cancer through the lens of metabolism and immunity.

Thanks from my deep heart to @puigserver_lab @PpuigserverB, Kai Wucherpfennig, Hans Widlund, Jean Zhao, and everyone at @DFCI_CancerBio and @harvardmed for your mentorship and support. Excited for what’s ahead!

Pan & colleagues identified a novel role of #PVSC-derived #PGC-1α in regulating #PVAT plasticity & the pathogenesis of #aneurysms. Learn more at ahajrnls.org/44uVCQW @CVR_TomaszGuzik

A vascular perspective on #cancer cachexia here restoring endothelial PGC1α activity preserved vascular density and muscle mass in tumor-bearing mice @NatureCancer nature.com/articles/s4301…

Happy to share the new publication from our lab, identifying a new assembly factor of CI involved in disease!!!‼️🚨#mitochondria Time-resolved mitochondrial screen identifies regulatory components of oxidative metabolism | EMBO reports embopress.org/doi/full/10.10…

RBM43 controls PGC1α translation and a PGC1α-STING signaling axis dlvr.it/TJPmDw

Polyplex Nanomicelle‐Mediated Pgc‐1α4 mRNA Delivery Via Hydrodynamic Limb Vein Injection Enhances Damage Resistance in Duchenne Muscular Dystrophy Mice - Du - Advanced Science - Wiley Online Library advanced.onlinelibrary.wiley.com/doi/10.1002/ad…

Latest paper from our group, coming out in the March 25th issue of Cell Reports: The pro-inflammatory cytokine IL6 suppresses mitochondrial function via the gp130-JAK1/STAT1/3-HIF1α/ERRα axis cell.com/cell-reports/f…

The potential link between obesity and cancer is not new. But there is very little data showing that weight-loss interventions reduce cancer risk. See what our researchers are doing to learn more about the obesity-cancer connection: bit.ly/40JZbQb

Register now for @CellSymposia #CSMetabolites2025, May 11–13, 2025, in Sitges, Spain! Explore cutting-edge research with world-class experts in a stunning location. Early registration discount deadline: March 28! hubs.li/Q0375WQd0 #CSMetabolites2025

Matthew Ravichandran ’23 Wins ASA Early Career Scientist Award for Bridging Faith and Science  stories.gordon.edu/matthew-ravich… via @@gordoncollege Congratulations Matthew!

Does the lack of correlation between PGC1a RNA and protein give you a headache? Us too. Phillip Dumesic has uncovered a key factor controlling PGC1a mRNA translation authors.elsevier.com/a/1kdIZ5WXUlaX…

New! Online now: RBM43 controls PGC1α translation and a PGC1α-STING signaling axis dlvr.it/TJ23QD

(1/3) Excited to share our latest work using @CancerDepMap to uncover a new synthetic lethality in two distinct patient populations! We found that SKI complex inactivation through two independent genomic alterations creates a dependency on PELO nature.com/articles/s4158…