Madam Mitochondria

Mitochondrial control of inflammation | Nature Reviews Immunology nature.com/articles/s4157…

Efficient intervention for pulmonary fibrosis via mitochondrial transfer promoted by mitochondrial biogenesis | Nature Communications ⁦@PathfinderEq⁩ nature.com/articles/s4146…

Nanotube-mediated mitochondrial transfer: power to the T cells!: Trends in Immunology cell.com/trends/immunol…

Although trafficking of exogenous mitochondria assoc w transfer has been reported through tunneling nanotubes in vivo & EVs (such as exosome and exopher), the phenomenon of substitution has never been recognized in the context of true transfer. mdpi.com/2073-4409/12/1…

PDLSCs are a class of MSCs derived from periodontal ligament & are ideal seed cells for tissue regen due to their superior osteogenic differentiation potential. PDLSCs cultured on low stiffness hydrogels were restored by mitochondrial transfer. sciencedirect.com/science/articl…

Textbook oxidative phosphorylation needs to be rewritten: Trends in Biochemical Sciences ⁦@MitoPsychoBio⁩ ⁦@mitorandy⁩ cell.com/trends/biochem…

The role of mitochondrial transfer in the suppression of CD8+ T cell responses by Mesenchymal stem cells; @PathfinderEq stemcellres.biomedcentral.com/articles/10.11…

Exogenous mitochondrial transfer to human lung cells reverses TGF-β-induced mitochondrial dysfunction and reduces pulmonary fibrosis; @PathfinderEq @andy_d_lee @CoCo_Headley @MitoPsychoBio mdpi.com/1422-0067/25/2…

Hijacking the powerhouse: Mitochondrial transfer and mitophagy as emerging mechanisms of immune evasion: Molecular Cell cell.com/molecular-cell…

We propose that skull bone marrow harbours a protected and dynamically expanding bone marrow microenvironment, which is relevant for experimental studies and, potentially, for clinical treatments in humans. nature.com/articles/s4158…

Treatment with osteoblast-secreted #mitochondria significantly enhanced bone #regeneration in mice, suggesting the potential of mitochondrial transplantation therapy for #bone healing; academic.oup.com/jbmr/article/3…

The ⬇️ in mitochondrial respiration in DPP4− APCs rendered the cells competent to undergo osteoblast differentiation. These results are very important, because they indicate that mitochondrial activity greatly influences mesenchymal lineage determination. cell.com/cell-stem-cell…

Mitochondria-enriched hematopoietic stem cells exhibit elevated self-renewal capabilities, thriving within the context of aged bone marrow | Nature Aging nature.com/articles/s4358…

Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness. aging-us.com/article/206213…

Epimorphic regeneration in the mammalian tympanic membrane | npj Regenerative Medicine nature.com/articles/s4153…

#Mitochondria-targeting materials and therapies for #regenerative engineering sciencedirect.com/science/articl….

So many of our dreams at first seem impossible, then they seem improbable, and then, when we summon the will, they soon become inevitable.”  —Christopher Reeve