Akos Nyerges
@AkosNyerges
#SyntheticGenomics #GenomeEngineering & #DirectedEvolution | Research Associate at @harvardmed, George M Church @geochurch's lab | @NIH @NIBIBgov K99/R00 Fellow
Today in @Nature we share our work describing • how to achieve resistance to natural viruses, • a technology that prevents the escape of engineered genetic information, • how viruses overcome genetic-code-based resistance. nature.com/articles/s4158…
Congrats to Nilmani, Steve, Tianhao, Jingxia, Adrianna, and Ocean for developing an AI-powered autonomous protein engineering platform (nature.com/articles/s4146…). See news release: news.illinois.edu/self-driving-l…).
We are sponsoring travel grants for US PhD students to attend ICML this year! Apply below or share on to students who might benefit from this!
University budgets everywhere are getting slashed, and we hear many PhD students with accepted ICML papers can no longer afford to attend. We are stepping in to offer travel grants for researchers who lost funding. Sponsored by Pillar VC, Ormoni Bio, Latent Labs, and Cimulate
If you love #viruses, #ribosomes, and genomic #darkmatter, this thread is for you!! 💫 We're excited to share our published work developing Massively Parallel Ribosome Profiling (MPRP), which uncovered ~4,000 hidden proteins in ~700 viral genomes. science.org/doi/10.1126/sc…
Predicting the translation efficiency of messenger RNA in mammalian cells go.nature.com/4mgXR0C
After a long sleep, environmental remediation with live biologics is back to the mainstream R&D agenda at this side of the pond. Wanna join an EU-wide on line conversation with bioremediation stakeholders this Nov 10? Express interest and register here 👉 forms.cloud.microsoft/e/b7xVz7dJcu
Advances in DNA-synthesis technologies are allowing large volumes of DNA to be pumped out a low cost go.nature.com/46XgtOz
It’s July 20th, the anniversary of the Apollo 11 moon landing in 1969 — I hope for all of science and humanity that we, as a civilization, continue to dream and aspire. As JFK said: “We choose to go to the moon. We choose to go to the moon in this decade and do the other…
We traveled to DC to talk to Congressional Staffers about the impact of @NIH @NIBIBgov funding. It enables us to develop synthetic biology tools to advance cell & genetic medicines for patients in need. REPOST to deliver the message that SCIENCE saves lives & makes America great!
Comparing LigandMPNN and Directed Evolution for Altering the Effector-Binding Site in the RamR Transcription Factor A new study delves into the challenging realm of designing allosteric transcription factors (aTFs) using machine learning (ML) tools, a frontier less explored…
CASP is getting cut by NIH... 😢 (Anyone with extra funds wanna help support perhaps the most important competition of the century?) science.org/content/articl…
This Lancet figure shows estimated deaths from 10 vaccine-preventable diseases across 98 countries - with and without vaccination. Look at measles. The gap between the lines is staggering. And the confidence intervals are tight - we know these vaccines save lives. This progress…
Gavi has helped vaccinate over a billion children and save more than 150 million lives. Measles deaths dropped from 500,000 to under 50,000. Now the U.S. is pulling support - while exporting anti-vaccine misinformation that’s undermining trust far beyond our borders. The…
I did a hour long lab meeting recently and told everyone in the lab to use all the AI tools extensively for research purposes. AI is not going away. But, if we don't learn how to use it efficiently, probably we will fall behind.
I use all the help I can get—from AI and beyond—because most academic papers are poorly written, and too many are outright fraudulent…
So you want to change transgene expression: just change your promoter, right? Changing the promoter increases RNA and thus protein levels. What more could be happening? [1/n] Well, promoters don’t just set RNA levels; they uniquely transform how RNAs are transmitted into protein…
Out Now! Defining ultra-slow-growing extremophilic microorganisms as aeonophiles bit.ly/3HRzK9F #Microbiology #Extremophiles #Aeonophiles
Identification of non-canonical peptides with moPepGen go.nature.com/3HYJyyz
Registration is Now Open for the 2025 AIChE® Annual Meeting! The must-attend conference for chemical engineers, R&D scientists, and academic leaders at all career stages. Join a vibrant global community this November in Boston: bit.ly/463pyVt #AIChEAnnual #AIChE2025
📣 Applications now open PATH award supports early-career researchers studying the pathogenesis of infectious diseases in humans 💰 $505K over 5 years 🔬 For assistant professors 📅 LOI due: 07/17/25 Apply now 👉 buff.ly/qcSSxbq
With the help of a technique called Massively Parallel Ribosome Profiling, researchers in Science have identified more than 4000 open reading frames—stretches of genetic material that can encode proteins—across 679 human-associated viral genomes. scim.ag/44mWZB6
Our review on the versatile roles of phage-encoded tRNAs is out. Great work @DaanFvdBerg authors.elsevier.com/a/1lHYB,L%7EyC…
Thank you @carlzimmer @nytimes for covering our new study and the miraculous universe of microproteins! 💫 nytimes.com/2025/06/12/sci… @PardisSabeti @ScienceMagazine @broadinstitute @harvardmed