Yichi (Tony) Zhang
@tony_zhang_phd
Believer of serendipity in science & life. Canadian, Bball fan. PhD w. Eric Olson at UTSW, Damon Runyon fellow w. Matt Vander Heiden at Koch Institute in MIT
Excited to receive an NIH K08 Clinical Investigator Award to support my research on #mitochondria #peroxisomes 😀 The $775K will be critical in helping me transition to independence as I begin looking for a place to start my lab 🙏🏻 @A_P_S_A @the_asci @AmerAcadPeds #neotwitter
It’s with deep regret that I share the passing of my master of science mentor, Dr. Kenneth B. Storey. Ken was a renowned scientist from Carleton university. More than that, he was a man who inspired me to pursue a career in science. For that I’m forever grateful. Goodbye Ken


Muscle mass predicts lifespan better than BMI or weight - so get moving and get lifting
While I’m a big fan of new technologies that help us study human biology…there’s still no replacement for animal research! I wrote an article outlining this in @GENbio genengnews.com/topics/transla…
This has to be the best? or worst poster I've ever seen 😂
Johnny Furphy : 15 points (5-9 shooting, 1-3 from 3 & 4-5 from the FT line), 6 rebounds, 2 steals & 2 blocks in 31 minutes
Losing your mentor is a painful experience. When asked “what do you consider to be your greatest achievement? Dr. Ken Storey always said “My students!” Thank you for the countless lessons in science and life, the jokes, and the music! @CarletonScience
So excited to see this amazing work published from an amazing friend and colleague. It's amazing to see that PHF7 alone has such an effect on restoring cardiac function after MI. Congrats @glynnis_bann
Excited to share our study out in Circulation identifying the ability of PHF7 to activate cellular reprogramming and recover function in the heart following myocardial infarction. Grateful to @Transactivator and the great team who made this work possible! ahajournals.org/doi/10.1161/CI…
Excited to share our study out in Circulation identifying the ability of PHF7 to activate cellular reprogramming and recover function in the heart following myocardial infarction. Grateful to @Transactivator and the great team who made this work possible! ahajournals.org/doi/10.1161/CI…
Guess we’re gonna have to ask our favorite AI chatbots to predict drug efficacy instead of doing preclinical studies now
NIH no longer award funding to new grant proposals solely relying on animal testing. drugdiscoverytrends.com/nih-announces-…
As promised, a 🧵 on our recent article now out in @NatureSMB! Co-led with @AbbyBartlett_ @Pagliarini_Lab @JudithSimcox, we find ACAD10/11 are NOT like other acyl-CoA dehydrogenases and instead catabolize atypical lipids called 4-hydroxy acids 🤯#lipidtime doi.org/10.1038/s41594…
This is effectively a cure for type 1 diabetes. Autologous, (chemically) reprogrammed iPSCs were engineered from a patient's fat cells and injected back into her stomach. After ~2.5 months, she no longer needed insulin and now enjoys ice cream + candy like a normal person.
I'm excited to share that I will be starting my lab at NTU Singapore. It is bittersweet to be moving halfway around the world. On one hand, I'm excited for a new adventure. I have spent my entire adult life chasing this dream, and it's finally happening. On the other hand, I…
AHH!! My primary thesis work is finally out! Tweetorial to come...
New online! ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism bit.ly/4kNfh4m
It's official - I am thrilled to share that I am joining @MITBiology, the @kochinstitute, and @MIT_IMES as an Assistant Professor this fall! We will be a hybrid lab combining new technologies and computation to study ecDNA and tumor evolution. thejoneslaboratory.com
Thrilled to share that the last paper of my postdoc is now out in @Nature ! We show how metabolic rewiring through OGDH drives tissue regeneration and stem cell fate. A wild and rewarding ride—huge thanks to @ScottMillmanMD and the @LoweLabMSKCC ! nature.com/articles/s4158…
Two guys in the front row at the Pacers game dressed like Dumb and Dumber with Stephen A Smith and Kendrick Perkins faces on their suits 😂😂😂
Over the last 2 weeks, I took a deep dive into Evo 2, Arc's Genomic Foundation model. But, I couldn't find a crisp primer on Evo 2 that covered the decisions for the ML architecture, the inference-time scaling results or the mechanistic interpretability results. So, I wrote one!
Announcing Evo 2: The largest publicly available, AI model for biology to date, capable of understanding and designing genetic code across all three domains of life. arcinstitute.org/manuscripts/Ev…
In 2019, a postdoctoral research fellow and a PhD student working with me were having a conflict about the authorship on a paper. She previously agreed to work with a student on the study. The student wanted more credit for the time she was spending. We made a deal that the…
From River Xiang to Harvard, from Columbia to Today: Reflections at a Critical Moment Nearly 40 years ago, I came from China to the U.S. with $50 in my pocket. I was fortunate to pursue graduate studies through the Harvard-MIT Health Sciences and Technology program — one of the…
KAT IS HILARIOUS BRUH Even his passes be SASSY lmaooo 🤣