David Sinclair
@davidasinclair
Professor @Harvard researching why we age & how to reverse it. Author & host of Lifespan. Mission: Extend healthy life for all. Views are entirely his own 🙏✌️
Chronic inflammation speeds up every hallmark of aging. Have your inflammation levels tested: CRP, IL-1b, TNF-a, Lp-PLA2, and food sensitivities
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We are excited to announce a research collaboration with SingHealth Duke-NUS Regenerative Medicine Institute of Singapore (REMEDIS) to further expand our pipeline of cellular rejuvenation therapies. Read more:bit.ly/45hhaAU
Strength training twice a week cuts cancer death risk by 31%
A future without disease IS POSSIBLE.
Time-restricted eating improves insulin sensitivity and lowers blood pressure, even without weight loss. —Cell Metabolism, 2018
>80% of urine samples from children and adults contained a weed killing chemical called glyphosate which has been linked to cancer and Alzheimer's risk. Another reason to eat organic, at least for certain foods likely to be contaminated. wwwn.cdc.gov/Nchs/Nhanes/20…
It’s baffling how a double-blind placebo-controlled trial testing NMN can show reductions in BP, LDL, trigs, body weight, and some still claim NMN doesn’t do anything. A drug that did that would be global news and worth billions academic.oup.com/jcem/article/1…

This is significant. AI is increasingly the place to go for health info - but it’s full of errors. Team’s working hard on a solution….
Interesting/a bit unnerving to see that health is the one plummeting the fastest here! That’s the place where AI hallucinating nonsense could be directly and seriously harmful, and there’s plenty of health misinformation in the training data…
The average American spends 11 years in poor health at the end of life - unless they work health years before the diseases set in
Metformin users have a 15–20% lower risk of all-cause mortality, even if non-diabetic
People with low grip strength have up to 3× higher mortality risk —Lancet, 2015
High-sensitivity CRP >2.0 mg/L doubles the risk of heart attack. —Ridker et al., NEJM (my cardiologist)
🧵1/ A rigorous new study from Chile’s oldest birth cohort (Santiago Longitudinal Study, N=947, mean age ~30) finds that long-term obesity accelerates biological aging—according to three DNA methylation-based aging biomarkers. Here's why it matters. 👇 Reference: Long-Term…
Childhood physical activity associates with adult fitness & lower risks of disease. Cause or effect? In mice, early-life exercise enhances late life metabolism, cardio function, strength & reduces frailty in old age. The epigenome never forgets. nature.com/articles/s4146…
