Arc Institute
@arcinstitute
A new scientific institution for curiosity-driven biomedical science and technology.
Our 2nd Annual Investigator Retreat wrapped up with talks covering immunology and technology development from Core Investigators @ChristophThaiss and @FelixHorns, our incoming Science Fellow @maya_arce_, and our Innovation Investigators and Ignite Awardees @icclarker, Calvin Kuo,…




The Arc Institute Investigator Retreat is off to a great start! Huge thanks to @davey_burke and @BrianHie for sharing their computational research, and to @ishahjain, Will Allen, @FaranakFattahi, and @brainevodevo for diving into cell biology and neuroscience.



Our work with the STATE model tackled context generalization for *seen* perturbations. @arcinstitute's Virtual Cell Challenge (VCC) focuses on a more challenging scenario: context generalization for *unseen* perturbations. Colab notebook to train your own STATE models for VCC:…
“You need to have appreciation for the real molecular mechanism of a pathway, and you really need to study it until the last residue. Until then, you can’t develop potent inhibitors.” ~ Arc Core Investigator @li_lingyin
Activation of the stimulator of interferon genes (STING) pathway can be great for fighting pathogens and treating cancer. But when the pathway is too active, it can do more harm than good, aggravating autoimmune and neurodegenerative diseases. cen.acs.org/analytical-che…
Come join the bridge editing team @arcinstitute and build the future of genome design!
Happy to share that I'm continuing my research on bridge recombinases as a scientist in @pdhsu lab at the @arcinstitute! I am looking for a motivated post-grad to work with me as a research associate. If you are interested or know of someone, please use the link below:
STING Inhibition Differences Revealed Between Humans and Mice Mechanistic discrepancies between species highlight the limitations of mouse models in advancing STING inhibition drugs for various diseases @arcinstitute #immunecells #mice #therapeutics hubs.li/Q03vPvl80
Getting to the virtual cell is the holy grail of life science. Now there's a challenge on to accelerate it cell.com/cell/fulltext/… @arcinstitute @CellCellPress @nvidia @10xGenomics @yusufroohani @StanfordAILab @davey_burke @UltimaGenomics
Love the enthusiasm @nalidoust! Virtual Cell Challenge entrants who are happy to share their models will benefit the entire field.
I f*** love this. And to put even more momentum behind this awesome movement by our @arcinstitute friends: 🥁@tahoe_ai will give $25K to the best model that is also open-sourced with weights on @huggingface for everyone's use! + maybe a mention on X by @ClementDelangue? ;)
How close are we to simulating living cells? Today @arcinstitute is launching the Virtual Cell Challenge (VCC), an annual competition for evaluating progress towards a virtual cell. Read our @CellPressNews commentary