Seth Bannon (@sethbannon)

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Seth Bannon@sethbannon · Jul 15

Plasmidsaurus is wild. 10 labs. 4 countries. Profitable from day one. Customers were stunned by their overnight turnaround time. So what did they do? Rolled out same-day. Hear the story in Happy Warriors, our new video series.

FFifty Years@fiftyyears · Jul 15

Introducing Happy Warriors -- stories of founders building what civilization needs. Episode 1 is here, featuring @Plasmidsaurus, the startup quietly speeding up biology worldwide.

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Elicit@elicitorg · 9 h

Clinical Trials are live on Elicit 🎊 You can now search through the 545,000 trials available on clinicaltrials.gov and summarize them in structured tables or descriptive reports. New trial registrations are instantly available.

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Seth Bannon@sethbannon · 18 h

Fifty Years has been cooking 🍳 a very cool event for those interested in translating their research!! Stanford, Berkeley, UW and Caltech, this is your chance :)

FFifty Years@fiftyyears · 23 h

Startups are the best way to scale the impact of research. At 50Y, we've helped 100s of scientists go from lab bench to founding. Want to learn how deep tech companies get started and how to grow into a great founder? Join us at Stanford, Berkeley, UW, or Caltech 👇

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Seth Bannon@sethbannon · 23 h

We're coming to Stanford, Berkeley, UW, Caltech to help more scientists start companies.

FFifty Years@fiftyyears · 23 h

Startups are the best way to scale the impact of research. At 50Y, we've helped 100s of scientists go from lab bench to founding. Want to learn how deep tech companies get started and how to grow into a great founder? Join us at Stanford, Berkeley, UW, or Caltech 👇

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Fifty Years@fiftyyears · 23 h

Startups are the best way to scale the impact of research. At 50Y, we've helped 100s of scientists go from lab bench to founding. Want to learn how deep tech companies get started and how to grow into a great founder? Join us at Stanford, Berkeley, UW, or Caltech 👇

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Rohan Krajeski@RohanKrajeski · Jul 22

5050 taught me this: great science isn't enough. You need to deeply understand the problem you're solving.

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Seth Bannon@sethbannon · Jul 21

A "MODIFIED SAFE" IS NOT A SAFE The point of the SAFE is that it's standard. Everyone knows they're getting a fair deal. Too many VCs claim they're "using a SAFE" when in reality they've added a bunch of special terms and conditions. If you don't see this in the doc, watch out.

sethbannon's tweet image. A "MODIFIED SAFE" IS NOT A SAFE

The point of the SAFE is that it's standard. Everyone knows they're getting a fair deal. Too many VCs claim they're "using a SAFE" when in reality they've added a bunch of special terms and conditions. If you don't see this in the doc, watch out.

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Seth Bannon@sethbannon · Jul 21

ראשי מערכת הביטחון- הרמטכ״ל, ר׳ המוסד ומ״מ ר׳ השב״כ, פינוי אוכלוסיה שלמה מבתיה ללא אבחנה, הריסת בתיה באופן שיטתי וריכוזה בתא שטח מצומצם ב״עיר הומניטרית״, לצורך ״גירושה מרצון״ - זו סדרה של פשעי מלחמה על פי דין, שלא לדבר על ערכי המוסר שלנו. הרעבת אוכלוסיה, כדי להביאה ל״גירוש מרצון״…

ממשה 'בּוֹגִי' יעלון@bogie_yaalon · Jul 21

ראשי מערכת הביטחון- הרמטכ״ל, ר׳ המוסד ומ״מ ר׳ השב״כ, פינוי אוכלוסיה שלמה מבתיה ללא אבחנה, הריסת בתיה באופן שיטתי וריכוזה בתא שטח מצומצם ב״עיר הומניטרית״, לצורך ״גירושה מרצון״ - זו סדרה של פשעי מלחמה על פי דין, שלא לדבר על ערכי המוסר שלנו. הרעבת אוכלוסיה, כדי להביאה ל״גירוש מרצון״…

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Grok@grok · Jul 20

LouisRLCM Food aid to Gaza is severely restricted: as of mid-July 2025, only ~250k daily meals for 2M people, with 500k in starvation per UN OCHA. Trucks average <100/day, far below needs. Photos may show less affected; malnutrition hits children hardest (e.g., emaciated cases…

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Seth Bannon@sethbannon · Jul 19

The most bizarre sort of fantasy. The markets don't want this. Utilities don't want this. Frackers certainly don't want this. No one who breaths air wants this. Drill baby drill, while vacuous, at least nods to commodities in demand.

UU.S. Department of Energy@ENERGY · Jul 19

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Seth Bannon@sethbannon · Jul 19

The President of the United States is suing one of America’s most respected newspapers over critical reporting. I’m sure all the free speech warriors on the right will rush to condemn this. Right? Right?

sethbannon's tweet image. The President of the United States is suing one of America’s most respected newspapers over critical reporting.

I’m sure all the free speech warriors on the right will rush to condemn this.

Right?

Right?

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Seth Bannon@sethbannon · Jul 18

Steve Jobs on "agents" in 1984: "The types of computers we have today are tools. They’re responders: you ask a computer to do something and it will do it. The next stage is going to be computers as 'agents.' In other words, it will be as if there’s a little person inside that…

sethbannon's tweet image. Steve Jobs on "agents" in 1984:

"The types of computers we have today are tools. They’re responders: you ask a computer to do something and it will do it. The next stage is going to be computers as 'agents.' In other words, it will be as if there’s a little person inside that…

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Seth Bannon@sethbannon · Jul 17

Wow, so cool that your cloud agent can almost do what my laptop has been doing this whole time. Except mine already has my logins, apps, and context. And doesn’t cost $0.15 per click. 🙃

OOpenAI@OpenAI · Jul 17

ChatGPT can now do work for you using its own computer. Introducing ChatGPT agent—a unified agentic system combining Operator’s action-taking remote browser, deep research’s web synthesis, and ChatGPT’s conversational strengths.

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Seth Bannon@sethbannon · Jul 17

At @fiftyyears we almost exclusively back deep tech founders. Substack is a rare exception. Why did we lead their seed? Because they’re building something civilization needs. Culture is an essential input to progress. But today, social media distorts culture -- toward…

HHamish McKenzie@hamishmckenzie · Jul 17

We’ve raised $100 million that we will put to work for creators and their audiences. Ownership for creators. Agency for audiences. Substack is a network built in service of people who care about culture. I’m pumped for this. Now we go big.

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Seth Bannon@sethbannon · Jul 16

When someone's falling apart online and your impulse is to joke, take a beat. They're likely carrying something heavy. Try compassion instead. It's better for everyone, you included.

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Seth Bannon@sethbannon · Jul 16

I've observed @markwbudde since the early days. Even then, he understood the need and was willing to do the tedious work of building an excellent operation and business first, which is rare. Love seeing all the scientists who are enabled by their products now.

MMark Budde 🦕🏆@markwbudde · Jul 16

Had a great chat with @fiftyyears telling the @plasmidsaurus story for their new Happy Warriors series. At Caltech, I was so frustrated with the stagnant DNA sequencing industry that I started a company out of my garage. Now we accelerate science around the globe, every day.

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Seth Bannon@sethbannon · Jul 15

The number of times I mention @plasmidsaurus to scientists and they start raving about how it has saved them days of work, massively accelerating their experiments is wild. Tune in to Happy Warriors to learn how deep tech founders are quietly sparking revolutions.

FFifty Years@fiftyyears · Jul 15

Introducing Happy Warriors -- stories of founders building what civilization needs. Episode 1 is here, featuring @Plasmidsaurus, the startup quietly speeding up biology worldwide.

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D. Scott Phoenix@fuelfive · Jul 15

What should you build in the age of AI? 🤔 I raised ~$250M from Elon, Zuck & Bezos for my AGI startup before selling to Alphabet in 2023. Join me at Stanford for my unhinged thoughts on the most important question of starting up: picking what to build. Register 👇

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Seth Bannon@sethbannon · Jul 15

Want to get even more fired up for the future? 👇

FFifty Years@fiftyyears · Jul 15

Founders building what matters most. That’s where hope begins. We’re relaunching the 50Y YouTube to tell their stories.

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