Rohan Krajeski
@RohanKrajeski
Curr.: PhD candidate @Cambridge_uni, 5050 UK Cohort 1 @FiftyYears VC | Prev.: @MIT, @UniofOxford, @UCL, Amaranth Foundation | #synbio #neuroscience #longevity
Delighted to announce the release of the Amaranth Foundation's latest white paper on combating brain aging (and 🧵👇): static1.squarespace.com/static/64becfb…
1/ The UK feels like a fully coiled spring, ready to unleash. It’s home to many of the finest technical minds on the planet, with 4 of the world’s top 10 research universities. But when it comes to turning science into world-changing startups, it’s lagging.
Precise DNA integration is key for many therapies, but inserting large, scarless sequences remains challenging. What if we could reprogram nature's mobile elements for programmable genome writing? Today we (+ @omarabudayyeh) debut Stitchr in @Nature
Super proud to have been a part of this work and thankful for the valuable mentorship of @jgooten and @omarabudayyeh 👏🏻
STITCHR was only possible as a massive team effort. Huge congrats to co-first authors @ChrisWFell, @lukas_villiger, Justin Lim, and Masahiro Hiraizumi; our collaborator @hnisimasu; @idmjky, @alisankayabolen, @_Dariomics_, @RohanKrajeski, and the rest of the AbuGoot Team!
Huge congratulations to first authors @ChrisWFell, @lukas_villiger, Justin Lim and Masahiro Hiraizumi on this work! This paper has been a long time coming! 👏
So excited to share our new paper out today in @Nature. We repurposed R2 retrotransposons to create STITCHR, a tool that can make diverse edits in mammalian genomes including scarless multi-kilobase scale insertions nature.com/articles/s4158…
Turning 32 (next week), but the lab decided to celebrate early… never thought I’d see my Google Scholar on a cake 😂
Super excited to share our recent work now out in @Nature! We introduce trans-synaptic tracing tools from circuit neuroscience to study the whole-brain connectome of glioblastoma. nature.com/articles/s4158…
Most synthetic biology efforts focus on individual cells. A biosensor, for instance, is typically built inside a single cell. That engineered cell is then "propagated" to form a clonal population, with each cell working in relative isolation. But this paper shows how communities…
Building on the growing success of the @CSHL meeting on 3D models and human brain development, I’m thrilled to announce an exciting new conference this December 2025: Assembloids and Complex Cell-Cell Interactions across Tissues and Organs. It’s an honor to co-organize this…
Harvard scientists are leaving academia for the private sector to fast-track biomedical breakthroughs. Michael Mina (eMed), Douglas Melton (Vertex), Stuart Schreiber (Arena Bioworks) cite funding delays & admin hurdles as key reasons. #BiomedicalResearch harvardmagazine.com/2025/01/harvar…
🚨 Interested in precise, multi-kilobase scale insertions into the genome? Check out our detailed protocol describing PASTE, out in @NatureProtocols ⬇️ nature.com/articles/s4159…
In NYC between 17-20th July! Down to grab coffee/lunch/dinner and discuss science! 🧬
The northern lights have made an appearance in the UK!
Beautiful and fruitful Friday afternoon working at @mng_ceb with amazing team members @belquis_haider @RohanKrajeski and Sulay Vora! Love this cute lab coat 🤩
Small molecule and cell contact-inducible systems for controlling expression and differentiation in stem cells ift.tt/5DfaRGQ #biorxiv_synbio
Come join us on March 7th at @Kings_College @Cambridge_Uni to hear more about Prof. Kouzarides and his career!
Amaranth retreat = done ✅. Spent the last 48 hours with an incredible team planning out some insane longevity moonshots for the coming year. Watch this space y’all! @jamesfickel @AlexJColville @RaianyRomanni @JoanneZPeng
