Mark Budde π¦π
@markwbudde
Co-founder & CEO - Plasmidsaurus π¦π¦π§¬ The only real DNA Sequencing as a Service company
Come build with us and accelerate the entirety of biotech. plasmidsaurus.com/careers
Can we use RNA to insert kilobases of DNA into the human genome, opening up a new way to engineer cells or treat disease? Excited to share our latest work turning a retrotransposon (a βjumping geneβ with an RNA intermediate) from songbirds into a genome editing tool. π§΅ (1/7)
Plasmidsaurus is wild. 10 labs. 4 countries. Profitable from day one. Customers were stunned by their overnight turnaround time. So what did they do? Rolled out same-day. Hear the story in Happy Warriors, our new video series.
Introducing Happy Warriors -- stories of founders building what civilization needs. Episode 1 is here, featuring @Plasmidsaurus, the startup quietly speeding up biology worldwide.
Introducing Eleven v3 (alpha) - the most expressive Text to Speech model ever. Supporting 70+ languages, multi-speaker dialogue, and audio tags such as [excited], [sighs], [laughing], and [whispers]. Now in public alpha and 80% off in June.
California should be the most agriculturally productive place on earth. We can make energy abundant and desalinate the ocean. Desal tech has advanced considerably, as has solar and nuclear. And the brine can be a feedstock for lithium, magnesium, and other critical minerals.β¦
No part of California is more than 350 miles from the ocean, a limitless supply of water. Every time an official wastes their life advising water conservation, or you drive past 100 miles of broke, fallow farms near the I5, or a city burns to the ground, remember. Waterβ¦
California should be the most agriculturally productive place on earth. We can make energy abundant and desalinate the ocean. Desal tech has advanced considerably, as has solar and nuclear. And the brine can be a feedstock for lithium, magnesium, and other critical minerals.β¦
Was looking at an issue of Scientific American from 1958 and I'm obsessed with the ads
Also true in biotech.
i left my phd before joining openai working in industry demands more rigor β you donβt just need to convince reviewer 2 with a nice graph and an ego-cite, it better actually work if itβs underwriting billions in research investment not saying it always pans out that way inβ¦
You heard that right β get full bacterial genome sequencing in 1 day. π€― Starting at $90. Order now: hubs.ly/Q03sGJW50 P.S. We're at ASM! Stop by booth 1241 to chat with us about our new services.
ChatGPT is a game changer for exploring foreign cities. I can take a picture of almost anything and get the backstory.

California is a coastal state, with unlimited sea water and solar energy. Water scarcity is a manufactured crisis. For less than we already spend on legacy water infrastructure, we could 2x our supply.
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This is exactly what happens inside our sequencing machines. π
Slowly but surely they are making a competent plasmid editor that lives in your browser. Bullish on the dinosaur.
π£ Coming soon to our plasmid viewer! You'll soon be able to see base-level alignments and feature labelsβbecause the details matter.
π£ Coming soon to our plasmid viewer! You'll soon be able to see base-level alignments and feature labelsβbecause the details matter.
Synthetic biology could enable new types of programmable therapeutics. Our new preprint introduces synthetic protein circuits that selectively trigger cell death in Ras-mutant cancer cells, with interesting advantages compared to existing approaches. biorxiv.org/content/10.110β¦
Wooow, never expected this level of speed, especially on Saturday. @plasmidsaurus
Day one! @ASGCTherapy has been fantastic so far. Had a quick look around the massive expo (and already identified @plasmidsaurus as my favourite booth (for the amazing swag/playing Jurassic Park π¦π¦
What's the best option for speech to text on a Mac? I used to use ChatGPT speech-to-text button, but now it crashes when the audio is more than about 60 seconds long. The integrated Mac speech to text is too inaccurate.