Julian Englert
@julian_englert
Engaging in self-constructive behavior. Protein data dealer at @adaptyvbio
Can you build this? Then come work with us at @adaptyvbio. Adaptyv is the cloud lab for protein designers. Our high-throughput wet lab enables protein designers to experimentally validate their proteins with the click of a button. We're building advanced molecular biology…
The biggest challenge for AI in biology isn't just models, it's the data used to train them. Standard biological data isn't built for AI. To unlock generative AI for drug discovery, we must rethink how we generate and capture data. 1/
People think i am making this up This is who got interviewed by them. 85% legacy stuff and their lobby arms
We need to bring back Lent, so there's a religious outlet for this form of aimless penance. Clearly it's a human need of some sort. But letting it feast on anti-AC, anti-nuclear, anti-energy sentiments is a European travesty.
Here you go - official survey by 🇪🇺 @EurobarometerEU The biggest hurdle to SME, startup and scale ups.. are the administrative burdens set by Member States and @EU_Commission Over 12 000 European companies surveyed. We ask @vonderleyen , @EU_Growth to 10x their ambition in…
SMEs in Europe remain ambitious but face major hurdles when trying to grow. The 2025 #Eurobarometer shows strong plans for expansion, yet barriers like regulation, skills gaps and late payments persist. Check out the Eurobarometer for more👇 europa.eu/!J88tQ3
Great work by the team at @chaidiscovery around @joshim5 & co! Was cool running wet lab validation for their new model Chai-2 on @adaptyvbio
Chai Discovery just released their new model Chai-2, validated on Adaptyv! Chai-2 enables generation of de novo proteins and epitope-specific antibodies using a multimodal generative architecture that integrates all-atom structure prediction and generative modeling. Chai…
not on my bingo card was james dyson engineering a mass production system for strawberries..."growing things is like making things, i'm a manufacturer, and so i suppose in a way ive approached farming from that point of view"
I have more twitter followers than George Church, Feng Zhang, David Liu.
I have more twitter followers than George Church, Feng Zhang, David Liu.
Future Eaux-Vives neighborhood vibe moodboard. Civic initiatives & courses incoming!
We're looking for talented people to join our team! Adaptyv is growing super fast and we need more hands on deck to manage our lab, BD and ops! Please send me a DM if you have recommendations for who we should hire
We're hiring! Come work with us to democratize protein engineering. At Adaptyv, our high-throughput cloud lab enables protein designers to experimentally validate their proteins with the click of a button. We're building advanced molecular biology workflows, assay automation…
Cool work by @hla_michael ! And nice job by our content machine @CotetTudor 💪 Want to test your own protein designs in our lab @adaptyvbio? Send us your ideas at [email protected]
Pro-1, a protein design model by @hla_michael, doesn’t just propose mutations — it explains why it made them. We tested 19 of its FGF-1 designs in our lab and 3 of them improved thermostability while maintaining binding. In this protein designer spotlight we explain how…
undisputed American cultural hegemony is European countries with kings having "no kings" protests bc the American left is upset with their president
This map shows some of the international locations of No Kings planned for tomorrow.
Excited to unveil Boltz-2, our new model capable not only of predicting structures but also binding affinities! Boltz-2 is the first AI model to approach the performance of FEP simulations while being more than 1000x faster! All open-sourced under MIT license! A thread… 🤗🚀
We're hosting a pretty epic summit this October in London. You'll probably enjoy coming if you're wrestling every day what it means to be human in a world of AGI, Robotics and advanced genetic medicine. Website is here: unrulyfutures.com
The way we regulate nuclear energy is insane
One principle makes nuclear power unaffordable. That’s Linear No Threshold: the theory that there is no safe level of radiation. It's wrong. But on Friday, the US President signed an executive order to reconsider it. 🧵 worksinprogress.co/issue/the-bad-…
Cool work by @hla_michael who designed proteins using his reasoning model Pro-1 and validated them in our lab at @adaptyvbio! We’re planning to run many more benchmarking and validation studies with people that have cool protein design idea! Reach out to me if you’re interested…
First Lab Validation for Reasoning Model Proteins With @adaptyvbio, we tested 19 FGF-1 sequences optimized by Pro-1 for thermal stability and binding affinity to human FGFR-1. Pro-1 produced 3 novel sequences that maintained binding affinity and expression compared to wild…
The grugbrained developer is on our mandatory cultural reading list. Inspired by it, I wrote up some general learnings from ~1.5 years as CEO of FutureHouse, on the topic of "How make tribe strong and be less confuse." Maybe useful, maybe not.
Unserious. Why would a good company raise money from the EIB when the world's best venture capitalists make decisions in days?
You should also go sit in a park and read @koeng101’s book
Over 20 years ago, Zuker et al. discovered the mammalian sweet taste receptors Now, an exciting collaboration between our labs @ColumbiaBiochem reveals the #cryoEM structure of the human sweet receptor-key to sweet taste perception-online @CellCellPress! sciencedirect.com/science/articl…
Speaking at @SynBioBeta today on the panel on “AI-Powered Biological Design”! We’ll explore where AI is accelerating protein design and discovery, where it’s still falling short, and how experimental and computational approaches can come together to unlock the next generation of…
