Patrick Collison
@patrickc
@Stripe CEO, @ArcInstitute cofounder.
This year, I read ten important historical novels: Jane Eyre, Middlemarch, To The Lighthouse, Bleak House, Portrait of a Lady, Anna Karenina, Life and Fate, Heart of Darkness, Madame Bovary, and The Magic Mountain. Reflections: • Four of these are more than 800 pages long. The…
Pieter Levels (@levelsio) and I sat down over a pint to talk about how he’s making $3m a year as a one-person company, what Europe can do to spur economic growth, and his experience as a digital nomad in over 150 cities across 40 countries. Timestamps 00:00 Intro 00:37 Pieter’s…
Best AI for shopping right now. No ads. Direct purchases within app with free shipping. No separate merchant checkouts. Commerce powered by Stripe.
At Perplexity, we’re excited about agentic shopping—helping users discover their next purchase, compare products, and buy seamlessly across many merchants. We’ve expanded our merchant coverage and improved our ability to fulfill complex shopping needs. Let us know what other…
One of the best parts of Stripe is working with the world's most interesting businesses. Taking advantage of this, we're launching a podcast where we host founders and leaders for a cheeky pint in our hastily-constructed office pub. Coming soon: episodes with @gdb, Meta’s Susan…
A conversation with @patrickc on old programming languages, software at industrial scale, and AI's effect on economics/biology/Patrick's daily life. 00:15 - Why Patrick wrote his first startup in Smalltalk 03:35 - LISP chatbots 06:09 - Good ideas from esoteric programming…
Stripe's usage-based billing platform has grown 145% YTD. There's lots of discussion about when the industry will shift from seat-based pricing to consumption models, but it's clear in our data that the transition is already happening. I'm curious what the second-order effects…
What will agentic commerce mean for the world? Emily covers this, Stripe's new foundation model, and more.
Had fun talking about all things AI at @stripe with @mattturck - agentic commerce, our new foundation model, and how we're boosting users’ revenue. youtube.com/watch?v=nvwglW…
We're very proud that 75,000 new businesses have started their journey with @stripe.
Atlas has now incorporated 75,000 companies! May was the largest month ever for startup formations on Atlas.
When I tell you I inhaled this book, I mean I read it in one sitting, then 7 times over again. I've recommended it 57 times, gifted 12 copies, and lovingly annotated it on 6 flights. Donald Braben's Scientific Freedom is an eulogy to scientific discovery, autopsied while it was…
It’s interesting to me that when we look for guidance on big topics like, ”What does it mean to be a good person?”, or “What makes for a meaningful, worthwhile life?”, many of the canonical texts we regularly refer to are very old. Nicomachean Ethics, Meditations and the Bible,…
Big news: we’re kicking off the search for ARIA’s next CEO. This is a once-in-a-lifetime opportunity to lead one of the most ambitious orgs in science and tech. 1/8
Register today for the Virtual Cell Challenge and use AI to solve one of biology’s most complex problems. Announced in @CellCellPress, the competition is hosted by Arc Institute and sponsored by @nvidia, @10xGenomics, and @UltimaGenomics.
"Slop" is one of the great coinages of the past few years. Kudos @simonw. (You should all follow his work if you don't.)
Congrats, @amasad! The rate at which great products like @Replit are growing usage and revenue continues to be quite remarkable. It's perhaps the most pro-upstart era we've ever seen. Like a lot of AI-native companies, Replit is built on @stripe's Optimized Checkout Suite (with…
.@Replit’s ARR since founding The space is … beyond on fire No one is going to code without AI again
Cells are dynamic, messy and context dependent. Scaling models across diverse states needs flexibility to capture heterogeneity Introducing State, a transformer that predicts perturbation effects by training over sets of cells Team effort led by the unstoppable @abhinadduri
Introducing Arc Institute’s first virtual cell model: STATE
Today @arcinstitute released the first version STATE, a virtual cell model. I wrote up a short blog post about it. You can check it out here: arcinstitute.org/news/virtual-c….
Introducing Arc Institute’s first virtual cell model: STATE
Arc's first virtual cell model. Am very excited about where this program is going.
Today @arcinstitute releases State, our first perturbation prediction AI model and an important step towards our goal of a virtual cell State is designed to learn how to shift cells between states (e.g. “diseased” to “healthy”) using drugs, cytokines, or genetic perturbations
Susan is amazing.
Susan Li is CFO of Meta and has never(!!) done a podcast. We talked about AI capex, whether your baseball hat should say FCF or EBITDA, how Meta allocates GPUs, and working with Mark Zuckerberg.