Darko Barisic
@edeon
Assistant Professor of Cancer Biology @WeillCornell NIH K99/R00 Fellow @theNCI Chromatin & Epigenetics in Cancer.
Thrilled to share we are @theNCI R00-funded. 🥳 Looking for computational biologists or bioinformaticians. 👩💻👨💻 We have many exciting projects on the role of chromatin remodelers in blood cancers. 🩸🦀 Please share/DM/email if relevant. Our latest story: cell.com/cancer-cell/ab…

Lab night out on Broadway! 🎭 A well-earned pause from experiments. 🧬 @SixBroadway

I'm excited to share my lab's first preprint! It describes Affinity Map, a highly general method providing proteomic profiles of binding affinity for small molecules, peptides, and antibodies in cell lysate, organ extracts, and live cell surfaces. biorxiv.org/content/10.110…
I am thrilled to share with the world a new preprint, spearheaded by the truly amazing Jose Reyes in partnership with @LoweLabMSKCC. Focused on the benign to malignant transition in PDAC, uncovering roles of plasticity, tissue remodeling and P53 -> biorxiv.org/content/10.110…
Huge congratulations to my postdoc Jiali Yu 👏 who has been awarded a fellowship from the National Cancer Center. @NCC_Org She’ll be investigating how chromatin remodelers contribute to the onset and progression of blood cancers. So proud and excited for what’s ahead. 🚀

Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality dlvr.it/TKg2CZ
Huge congrats to @LabMelnick on being appointed the Director of the Josep Carreras Leukemia Research Institute in Barcelona! 🙌 👏
We are pleased to announce that Dr Ari Melnick has been appointed new Director of the Josep Carreras Leukaemia Research Institute. Dr Melnick will lead IJC in our mission to advance #research in #leukaemia and other malignant blood diseases. Read the full release here:…
I'm running the NYC half marathon on March 15 to keep raising funds for ALS research - please donate if you can! Thank you. secure.als-ny.org/goto/ChrisMason
So what's happening with medical research in the US? This is the cumulative award count from the NIH for the year. Doesn't look so good. But it gets worse. 1/
Absolutely fantastic work from magnificent @Yael_David__ lab! Incredible science and amazing out-of-the-box approach. Congrats to all the authors and highly recommend the read. 🙌
I am extremely proud to see our work about Hepatitis B now published in @CellCellPress. From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵 cell.com/cell/fulltext/…
🧬 We’re excited to introduce D&D-seq, a single-cell technology that maps DNA:Protein interactions through molecular footprinting.. Check it out here: biorxiv.org/content/10.110… #Genomics #Epigenetics
#ASH2024 Highly recommend this place for lunch. Also, highly recommend the company @jchellmuth ❤️


Great morning session with Panagiotis Ntziachristos on Lymphoid Oncogenesis – Molecular Insights Into Lymphoma and CLL. #ASH2024

Huge congrats to Béguelin lab at @WeillCornell. Fantastic new work showing how PRC2 inhibition boosts T cell immunotherapies. Out now in @Cancer_Cell. cell.com/cancer-cell/fu…
After recent changes to Elon Musk’s X, Bluesky has rapidly emerged as the new online gathering place for researchers. bit.ly/40UT4u3
🦋 for Science Starter packs for genomics, bioinformatics, #Rstats, Nextflow. Moderation lists. Feeds. Let's rebuild the old scitwitter community and keep this place nice. blog.stephenturner.us/p/bluesky-for-… 🧬🖥️🧪
Following the steps of my peers, I will be transitioning from X to the Bluesky 🦋 platform. I hope the rest of the scientific community follows. 🙌 Username: darkobar

Very sad that I will have to cancel my talk at the @Fusion_Conf Epigenetics Conference tomorrow due to travel issues. It looks like it will be a fantastic meetings with an amazing lineup of speakers and topics. See you next time hopefully. 🤞

Happy to contribute to this new preprint by @ElenaPugachev12, @boris_ctcf & Co. What determines differential CTCF binding, beyond DNA methylation and TF/nucleosome competition? Answer: a specific nucleosome downstream of CTCF motif. Directionality matters! biorxiv.org/content/10.110…
CTCF binding landscape is established by the epigenetic status of the nucleosome, well-positioned relative to CTCF motif orientation biorxiv.org/content/10.110…
Fantastic new work by @Anders_S_Hansen & Co. on chromatin architecture during M-to-G1 transition. 🙌 👏
(1/n) From @ViraatGoel @Irate_Physicist et al. collab w @blobelgroup @leonidmirny biorxiv.org/content/10.110… RCMC at the M-to-G1 transition reveals strong microcompartments between CREs (E,P) in mitosis, that weaken upon G1 entry Sims reveal chromosome compaction as key regulator