Chris Mason
@mason_lab
Professor of Genomics, Physiology, & Biophysics @WeillCornell Medicine. Co-Founder / COI @BiotiaNYC, @UrsaBio & @Onegevity (@thornehealth)
For 🌘Lunar, Mars missions, this study mined data across 🚀 plants (lettuce, arabidopsis) & humans (I4, JAXA, Twins), showing 🚀evidence of 🥬mineral deficiencies, disrupted calcium signaling, leaky gut syndrome; to argue for precision nutrition, pharmagenomics & bioengineered…
Just published in @Nature_NPJ , @bioastra and @NASAGeneLab uncover key challenges of eating plants grown on LEO —and solutions—for astronaut health nature.com/articles/s4152… Fantastic collaboration between brilliant people @mason_lab @EliahOverbey @Dr_Dick_Barker @RyanTScott
Our paper about extensive genomic data for a new broadly-consented pancreatic cancer cell line and matched normal tissue is now published at doi.org/10.1038/s41597…! Stay tuned for draft GIAB benchmarks for somatic variants, and assemblies from these data coming soon! 1/2
For other to learn more and considering joining any of the 9 topical Analysis Working Groups 🔗 awg.osdr.space/about Paper on the Open Science Data Repo, the expansion of @NASAGeneLab 🔗 doi.org/10.1093/nar/gk…
Thanks to @mason_lab for joining us for the 2nd talk in our new Center for Space Medicine Research seminar series at @CSRegenMedicine! 🚀 Fantastic talk on space -omics, humans adapting to the microgravity environment, and the biomedical future of space exploration.
reprogramming cells with transcription factors is our most expressive tool for engineering cell state traditionally, we found TFs by ~guesswork @icmlconf we're sharing @newlimit's SOTA AI models that can design reprogramming payloads by building on molecular foundation models
An honor to collaborate on this research between plant biology, nutrition, gut, and human health for 🚀🎉 The type of research which can only occur across disciplines. Kudos to the @bioastra team and all @NASAGeneLab Analysis Working Group members 💯
Any countermeasure developed to address the issue of leaky gut needs to address multiple factors simultaneously. The first would be the restoration of the intestinal barrier through support/stabilization of the mucous layer, protecting epithelial cell-cell junctions, or both. The…
"Feeding the cosmos: tackling personalized space nutrition and the leaky gut challenge" nature.com/articles/s4152…
I had the privilege of teaching an exceptional group of high school students earlier this summer at the @uaustinorg Summer Honors Program. Thank you @mason_lab for writing The Next 500 Years! It provided an excellent framework for discussing space colonization and genetic…
Counting my lucky stars⭐️ that not only do I get to work with these phenomenal scientists @JiwoonPark_ @mason_lab-but also give fun @CSHL lectures together 💪.Big thank you to @LGMartelotto @nicholas_navin Julea Vlassakis for uniting this #singlecell #spatial #dreamteam !
"Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair" nature.com/articles/s4159… congrats to the @WeillCornell lab team, Justin Zook, and @NIST for this key resource!
"Microbial growth in actual martian regolith in the form of Mars meteorite EETA79001"nature.com/articles/s4324…
Opening bid is $1.6M for a piece of Mars! sothebys.com/en/buy/auction…
BioAstra was thrilled to join @PittTweet's Space Health Research Day, organized by our advisor @AfshinBeheshti. Great insights shared by our Co-Founders @SaviGlowe & @mason_lab, and advisors @SylvainCostes, astronaut Kate Rubins & astronaut @johnpshoffner . #SpaceHealth…
“Give me your tired, your poor, Your huddled masses yearning to breathe free, The wretched refuse of your teeming shore. Send these, the homeless, tempest-tost to me, I lift my lamp beside the golden door!" —Emma Lazarus
I am happy to announce the my latest book - "Moonshot: A NASA Astronaut's Guide to Achieving the Impossible" - is now available in paperback! @gcpbalance
An adult human brain has about 400 miles of vasculature "highway" delivering nutrients, oxygen, and molecules
Recent work Ecological interactions and genomic innovation fueled the evolution of ray-finned fish endothermy science.org/doi/full/10.11…
🚀 Space Health Research Day – July 7 @PittTweet! Join @Astro_Kate7, @mason_lab, @ProfSaraSeager, @johnpshoffner, @CostesSylvain & leaders in space health & longevity. Discover how space research transforms medicine for Earth & beyond. @Pitt_Space 🔗 pi.tt/space-biomedic…
So cool, a novel archaeon with a super small genome and no metabolic genes! "An unprecedented level of metabolic dependence on a host, a condition that challenges the functional distinctions between minimal cellular life and viruses." biorxiv.org/content/10.110…