Cell Genomics

@CellGenomics

Cell Genomics is a new gold #OpenAccess and #OpenScience research journal that represents the forefront of #genetics and #genomics 🧬

Joined June 2020

855Following

8KFollowers

Pinned

Cell Genomics@CellGenomics · Sep 22, 2022

Meet with us to discuss your research or to learn more about the publishing process! hubs.li/Q01msqBt0

Cell Genomics@CellGenomics · Jul 18

Impact of polymorphisms on gene expression and splicing in response to exercise and diet-induced weight loss in human skeletal muscle tissues dlvr.it/TM00ws

CellGenomics's tweet card. Wang et al. conducted a 16-week lifestyle intervention in obese East Asians and profiled paired skeletal muscle transcriptomes. They identified hundreds of lifestyle-responsive and Asian-specific...

629

Cell Genomics@CellGenomics · Jul 17

Oncogenic roles of young human de novo genes and their potential as neoantigens in cancer immunotherapy dlvr.it/TLyzqP

CellGenomics's tweet card. Xiao et al. report 37 young de novo genes in humans within an updated genomic context. Their expression is temporospatially expanded across tumors. Depleting 57.1% of them reduces tumor cell prolif...

2.0K

Cell Genomics@CellGenomics · Jul 16

OmicsTweezer: A distribution-independent cell deconvolution model for multi-omics Data dlvr.it/TLy9XN

CellGenomics's tweet card. Yang et al. present OmicsTweezer, a unified deep learning framework for cell type deconvolution across bulk transcriptomics, spatial transcriptomics, and proteomics. By integrating optimal transport...

957

Cell Genomics@CellGenomics · Jul 16

The CST complex mediates a post-resection non-homologous end joining repair pathway and promotes local deletions in Saccharomyces cerevisiae dlvr.it/TLxxkV

CellGenomics's tweet card. Repair of DNA double-strand breaks is finely regulated to maintain genome integrity. Here, Ilioaia et al. demonstrate the contribution of the CST complex, known for its function at telomeres, to a...

387

Cell Genomics@CellGenomics · Jul 15

Exploring genetic adaptation and microbial dynamics in engineered anaerobic ecosystems via strain-level metagenomics dlvr.it/TLx6Zk

CellGenomics's tweet card. Ghiotto et al. track adaptive evolution over a year in a carbon dioxide-fixing anaerobic microbiota, leveraging strain-resolved metagenomics. They reveal long-term haplotype sweeps in Methanothermo...

354

Cell Genomics@CellGenomics · Jul 15

The extracellular vesicle transcriptome provides tissue-specific functional genomic annotation relevant to disease susceptibility in obesity dlvr.it/TLwtv0

CellGenomics's tweet card. Chatterjee et al. reveal that extracellular vesicles in the blood of obese individuals contain transcripts linked to pathways of inflammation and type 2 diabetes, providing potential avenues for...

606

Cell Genomics@CellGenomics · Jul 11

Stop codon context modulates NMD efficiency through translation termination kinetics dlvr.it/TLskTT

CellGenomics's tweet card. Nonsense-mediated mRNA decay efficiency varies unpredictably across transcripts containing premature termination codons. A new study by Kolakada et al. demonstrates that glycine residues preceding...

464

Cell Genomics@CellGenomics · Jul 11

Peripheral chromatin remodeling at the center of zygotic genome activation dlvr.it/TLsVw1

CellGenomics's tweet card. Pal and colleagues investigate the molecular regulation of LAD establishment in mouse preimplantation embryos. This study provides insights into the physiological remodeling of LADs, revealing that...

921

Cell Genomics@CellGenomics · Jul 11

SpaLinker identifies phenotype-associated spatial tumor microenvironment features by integrating bulk and spatial sequencing data dlvr.it/TLsNHY

CellGenomics's tweet card. Xiaojie Cheng et al. introduce SpaLinker, a novel framework that integrates spatial transcriptomics with bulk omics annotations to link tumor microenvironment features with clinical outcomes. This...

2.0K

Cell Genomics@CellGenomics · Jul 10

Pisces: A multi-modal data augmentation approach for drug combination synergy prediction dlvr.it/TLrrPQ

CellGenomics's tweet card. Hanwen Xu et al. propose a new machine learning approach, Pisces, to drug combination prediction by augmenting the existing dataset using 8 modalities of each drug. Pisces outperforms competing...

506

Cell Genomics@CellGenomics · Jul 10

Unraveling an enhancer-silencer regulatory element showing epistatic interaction with a variant that escaped genome-wide association studies dlvr.it/TLrgWX

CellGenomics's tweet card. Adjemout and Nisar et al. identify a dual enhancer-silencer regulatory element, the “ESpromoter.” They discovered an epistatic interaction between the ESpromoter haplotype and an LAX1 promoter...

2.0K

Cell Genomics@CellGenomics · Jul 10

Secure an exclusive 1:1 meeting with a Cell Press editor to discuss your research. Meetings are on-site only and you must be registered to attend the symposium #CSPrecisionGen25. Limited spaces! hubs.li/Q03wgqdC0 @CellSymposia

CellGenomics's tweet image. Secure an exclusive 1:1 meeting with a Cell Press editor to discuss your research. Meetings are on-site only and you must be registered to attend the symposium #CSPrecisionGen25. Limited spaces! hubs.li/Q03wgqdC0 @CellSymposia

385

Cell Genomics@CellGenomics · Jul 10

Early establishment and life course stability of sex biases in the human brain transcriptome dlvr.it/TLrRWx

CellGenomics's tweet card. Benoit-Pilven et al. explore the origins of the well-established sex differences in many brain-related phenotypes. Through comparing sex-biased gene expression in the prenatal and adult human...

375

Cell Genomics@CellGenomics · Jul 10

Single-cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization dlvr.it/TLrJ92

CellGenomics's tweet card. Liu et al. analyzed single-cell RNA sequencing from human bone metastases across eight cancer types, identifying three immune ecosystem archetypes. These archetypes demonstrate distinct yet converg...

602

Cell Genomics@CellGenomics · Jul 9

Sequential activation of transcription factors promotes liver regeneration through specific and developmental enhancers dlvr.it/TLqkhW

CellGenomics's tweet card. Llorens-Giralt et al. study how liver cells respond to partial hepatectomy by examining changes in gene activity and chromatin accessibility. They create a functional regulatory map of early liver...

105

6.0K

Cell Genomics@CellGenomics · Jul 9

CellWalker2: Multi-omic discovery using hierarchical cell type relationships dlvr.it/TLqYms

CellGenomics's tweet card. Hu et al. present CellWalker2, a graph-based model that improves comparisons of cell types across contexts and species. By integrating multimodal single-cell data and modeling hierarchical cell-type...

3.0K

Cell Genomics@CellGenomics · Jul 9

Phenotypic heterogeneity and plasticity in colorectal cancer metastasis dlvr.it/TLqKcg

CellGenomics's tweet card. Ogden and colleagues reveal regenerative and inflammatory cancer cell states in primary and metastatic colorectal cancer. They combine single-cell multiomics and spatial transcriptomics patient data...

2.0K

Cell Genomics@CellGenomics · Jul 7

Benchmarking of T cell receptor-epitope predictors with ePytope-TCR dlvr.it/TLnVH2

CellGenomics's tweet card. Drost et al. present ePytope-TCR, a unified framework of binding predictors for T cell receptors toward disease-derived epitopes. A comparative benchmark reveals biases and shortcomings of these...

567

Cell Genomics@CellGenomics · Jul 7

Coordinated regulation by lncRNAs results in tight lncRNA-target couplings dlvr.it/TLnKgm

CellGenomics's tweet card. Long non-coding RNAs are abundant and dysregulated in cancers, but their functions are largely unknown. Chiu et al. developed intelligent methods to infer their function, revealing that these poorly...

580

Cell Genomics@CellGenomics · Jul 7

Landscape and m6A post-transcriptional regulation of soybean proteome dlvr.it/TLn5bg

CellGenomics's tweet card. Yang et al. present a proteome and m6A methylome atlas encompassing diverse soybean organs. They explore the role of m6A in post-transcriptional protein regulation in soybeans and demonstrate that...

717