Jacob Geri

I'm excited to share my lab's first preprint! It describes Affinity Map, a highly general method providing proteomic profiles of binding affinity for small molecules, peptides, and antibodies in cell lysate, organ extracts, and live cell surfaces. biorxiv.org/content/10.110…

We are actively recruiting a postdoc interested in working on developing new chemical biology tools for protein interaction discovery. If interested, please email me at [email protected]! gerilab.weill.cornell.edu/team

The Geri Lab is recruiting postdoctoral scholars to develop photocatalytic proximity labeling and proteomics technologies. Chemical biologists and chemists who want to learn chemical biology are welcome! gerilab.weill.cornell.edu/team The view from our recently expanded NYC lab space:

Happy photocatalyst Friday from the 16th floor of @WeillCornell

Excited to announce that our group's work on chemical biology technology at Weill Cornell Medicine at is now funded via a NIGMS R35 MIRA grant!

I was really impressed by the recent crop of text prompt to image AI tools and wanted to see how they would depict molecular interactions. Needless to say, I'll stick with Illustrator for now. Prompt: "MDM2 interacting with a peptide" Result (DALL-E 2):

Excited to share our latest work out today in @J_A_C_S using µMap to identify new SARS-CoV-2 entry receptors on human cells. Great collaboration between @JacobGeri1, @MacMillan_Lab and the @PlossLab, and hugely enabling for discovering new COVID biology.. pubs.acs.org/doi/10.1021/ja…

Me: Can I have a #structure of my #protein of interest? Alphafold: We have it in the #database, no need to make new one. Structure in the database:

Amazing to see a plan come together! This paper unambiguously shows the tight labeling radius of antibody-targeted µMap labeling compared to other methods, and how reactive intermediate lifetime can be exploited to tune proximity labeling radii. pnas.org/doi/abs/10.107…

Two PhD students and one postdoctoral scholar joined the lab this summer! Welcome Noah, Charlie, and Peter! @chardw98 @Noahyardeny93 @94peter

New R21 on identifying novel drug targets is getting funded! Excited to be working with @JacobGeri1 here at @WeillCornell

Our TIMSTof Pro 2 (a cutting edge LCMS for proteomics) is now installed and fully operational! Here is a picture of Alan, the Bruker rep, manuvering it with help from Maxim and Zahir. It extends vertically into the ceiling, as all awesome instruments should.

cen.acs.org/biological-che… Hidden "-omes" lie beyond our technological horizons. This is a highly underrated problem in chemical biology.

Had a fantastic weekend in Princeton celebrating Dave's Nobel! It was amazing to reconnect with so many old friends (like Tao Wang, pictured) and group alumni (>75!)- an unforgettable experience. @dmac68 @MacMillan_Lab

I remember being 7 years old and watching the man who played Capt Kirk on TV. Today I got the chance to chat with the real life astronaut @WilliamShatner and it was out of this world. Talked about organocatalysis, blue origin & carbon removal and he even said hi to Jim McCusker!