Craig Wilen
@WilenLab
Physician-scientist. Dad. Husband. Associate Professor @yaleibio @yale_labmed. We study host-viral interactions #covid #norovirus @wilenlab.bsky.social
By flipping an evolutionarily disabled genetic switch involved in Vitamin A metabolism, researchers in Science have enabled ear tissue regeneration in mice. Learn more: scim.ag/44muTVr
How to pick the right lab for a postdoc if you want to stay in academia. [based on my experience in the US and partly Europe] 1. Make a list of possible groups in advance. Meet their students & postdocs at conferences. Listen to their feedback. Get opinions from the faculty in…
#WeekendRead! #EveryCellIsAnImmuneCell! Kaelberer Bohorquez &co show @Nature that via #TLR5 flagellin drives neuropeptide PYY release by gut colonic neuropod cells, activating vagal neurons that signal to #brain, reducing feeding via a “neurobiotic sense”! nature.com/articles/s4158…
We identified SAMD9 as a common sensor of cytosolic dsDNA and dsRNA molecules and a key host restriction factor of the infection of multiple dsRNA viruses in vitro and in vivo! rdcu.be/eiJHa
New paper! Combining epidemiology and experiments uncovers surprising drug-host-microbiome-pathogen interactions. Congrats @Aman_Kr25 @RobynTamblyn and the rest of the team. nature.com/articles/s4158…
Check out our paper @madisonstrine @KStDenis_ME @YalePediatrics @YaleIBIO
Exploring mucosal immune development and function in utero dlvr.it/TLrRcC
The July issue of Science #Immunology is out! This month's cover features a study that demonstrates how the transcription factor #SpiB regulates #TuftCell activation within the gut by inhibiting c-Kit and TSLP signaling. Read this research and more: scim.ag/3TiI6tB
A new paper discussing the importance of federal, institutional, and programmatic support for physician scientist trainees. The same can easily apply to biomedical trainees. We as a nation need to support the next generation of doctors and researchers! rdcu.be/etaiE
A powerful new piece in @NatureMedicine by APSA past presidents & board members discusses how funding cuts could disrupt the physician-scientist pipeline and future of biomedical innovation, and outline urgent solutions to safeguard the next generation. rdcu.be/etaiE
Memory T cell formation and phenotype varies across intestinal compartments: mucosalimmunology.org/article/S1933-…
news.yale.edu/2025/06/23/scr… @Yale_LabMed @YaleMed @YaleMedicine
On Sunday I traveled to the middle of the desert to capture this: The ISS against our sun. What I didn't expect: the sun producing a magnificent flare at the same time A once-in-a-lifetime shot I'm thrilled to share with you. See the uncropped shot or get the print in the reply
On leadership & support- meet the amazing first responder team (partial) who voluntarily worked during first 12h, in darkness, smoke, and ashes, to save a building's precious frozen biological samples (most saved). No words to describe the courage and dedication of these people.
For anyone who has had a federal grant cancelled, consider filling out this congressional survey for the Committee on Science, Space, and Technology (you can be on the record or anonymous) forms.office.com/pages/response…
In a new @Nature study, @YaleIBIO and @YaleIMed researchers say newly-discovered #TCells in the #brain carry information from the gut, with implications for conditions like #Parkinsons disease and multiple sclerosis: medicine.yale.edu/news-article/t…
Congrats to the authors @Yale on this exciting and important work! #BrainTCellsRule || The subfornical organ is a nucleus for gut-derived T cells that regulate behaviour | Nature nature.com/articles/s4158…
Congratulations to Mikey Grunst, #PhD! @YaleMicroPath @YaleMed medicine.yale.edu/micropath/news… #spikeprotein #microbiology
In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by @US_FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe,…
🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!