Alejandra Tomás
@TomasLab_ICL
Head of Section of Cell Biology and Functional Genomics @imperialcollege. Interested in spatiotemporal regulation of signalling of metabolically relevant GPCRs.
Lectureship position available in my section @ImperialMDR
Are you interested in developing a research programme in cell biology of diabetes? Do you work in pancreatic islets and/or other metabolically relevant cell types? We have a Lectureship position opening to establish a lab in our Section at @imperialcollege (link to apply below)
The GLP1 discontinuation rate in the real world is alarmingly high. 64% at 1 year and 84% at 2 years in those without diabetes‼️ Risk factors of discontinuation include lower income, older age, lower weight loss, cost, among others. 🔬Further research into the predictors of…
Good at bioinformatics? Keen learner? Come do a PhD with the Akerman Team! Fully funded for UK residents.. findaphd.com/phds/project/p…
Still time to apply to this Lectureship position in our Section. Deadline 25th March.
Lectureship position available in my section @ImperialMDR
Congratulations to @LilianeEleid who successfully passed her PhD viva yesterday! Here are some pictures of the post-viva celebrations. Many thanks to Prof David Hodson @daveyboyhod and Dr Bryn Owen @BrynMOwen for assessing her thesis and to David for his visit and Seminar.



Putting the brakes on mitochondrial fusion to prevent escape of mitochondrial DNA nature.com/articles/d4158…
Our newly revised manuscript on ER- mitochondria membrane contact site-localised GLP-1R signalling hub now out in bioRxiv: biorxiv.org/content/10.110…
A post over a decade in the making… 🙌beyond excited to share our work out today in @ScienceMagazine. We found that retrograde (mitonuclear) signaling regulates the identity and maturity of metabolic tissues.🧵 1/6 science.org/doi/10.1126/sc…
Our newest preprint about a new GLP-1R/GIPR dual agonist: biorxiv.org/content/10.110…
Last few days to apply for a postdoc position in my lab
A postdoctoral position is available in my lab @CellBiolMDR @ImperialMDR to study the subcellular organisation of signalling of the glucagon receptor family. For more information and to apply please click here: imperial.ac.uk/jobs/search-jo…
Our collaboration with the talented Sarah Rouse @ImperialLifeSci now out in bioRxiv: "Human class B1 GPCR modulation by plasma membrane lipids" biorxiv.org/content/10.110…
Still time to apply to this position! Application open until 15th Jan 2025.
A postdoctoral position is available in my lab @CellBiolMDR @ImperialMDR to study the subcellular organisation of signalling of the glucagon receptor family. For more information and to apply please click here: imperial.ac.uk/jobs/search-jo…
Open for submissions: The Impact of GIP/GIPR on Metabolic Diseases: How the Field Is Evolving @FrontEndocrinol frontiersin.org/researchtopic/…
Our attempt to tag endogenous GIPR in vivo with a Halo-tag biorxiv.org/content/10.110…
PhD Studentship available in the lab of Dr Paras Anand @anandparas at Imperial, in collaboration with me: findaphd.com/phds/project/d…
A postdoctoral position is available in my lab @CellBiolMDR @ImperialMDR to study the subcellular organisation of signalling of the glucagon receptor family. For more information and to apply please click here: imperial.ac.uk/jobs/search-jo…

Fantastic visit and talk from Aaron this past Thursday when he discussed his exciting work on GLP-1RAs! @ImperialMDR @ICL_Receptors @imperialcollege
Honored and excited to present our research on incretin-based molecular pharmacology at @imperialcollege @ICL_Receptors. Proud to represent @helmholtz_diabc
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New version of the preprint now in BioRxiv: In vivo functional profiling and structural characterisation of the human Glp1r A316T variant biorxiv.org/content/10.110…
The human Glp1r A316T variant exhibits characteristics of constitutive activation but dampened GLP-1RA responses @TomasLab_ICL @imperialcollege biorxiv.org/content/10.110… #T2D #obesity