Filippo Caschera
@Stjle
Synthetic Biology, Artificial Cells, Amphiphile Systems, Machine Learning, Cell-Free Protein Synthesis: Italy, Denmark, Japan, USA, France, Germany, UK.
Pleased to share my latest review on Cell-Free Protein Synthesis #CFPS and #AI/ML for accelerating drug discovery sciencedirect.com/science/articl… #CellFree #SynBio
"high-throughput phage isolation using droplet microfluidics" PRISM: A platform for illuminating viral dark matter biorxiv.org/content/10.110…
Self-assembling protein materials with genetically programmable morphology and size biorxiv.org/content/10.110… #biorxiv_synbio
New synbio tools 4 the fastest growing bacteria! Check this out! @ATinyGreenCell doi.org/10.1093/nar/gk…
Amphiphilic Copolymers and Their Role in the Study of Membrane Proteins | The Journal of Physical Chemistry Letters pubs.acs.org/doi/10.1021/ac…
Machine Learning-Guided Evolution of Pyrrolysyl-tRNA Synthetase for Improved Incorporation Efficiency of Diverse Noncanonical Amino Acids @NatureComms Researchers have developed a novel machine learning framework to engineer pyrrolysyl-tRNA synthetase (PyIRS), significantly…
Excited to dive into this book and explore the fascinating connections between organisms, business, and beyond. Curious to see how biology fits into the bigger picture. 🏖️☀️😎🌊
Cell-Free Expression of Nipah Virus Transmembrane Proteins for Proteoliposome Vaccine Design | ACS Nano pubs.acs.org/doi/10.1021/ac…
CF2H: a Cell-Free Two-Hybrid platform for rapid protein binder screening biorxiv.org/content/10.110… #biorxiv_synbio
Design-Build-Test-Learn guided engineering of a whole-cell pyruvate biosensor based on transcription factor biorxiv.org/content/10.110… #biorxiv_synbio
I love the idea of "micropublications" micropublication.org (preparing one now)
A Data Guided Approach To Building An ML Ready Protein Expression Dataset A new project aims to create an openly available and extensible experimental platform and standardized data ontology for collecting soluble recombinant protein expression data across organisms. The…
A Lactose-Based Kluyveromyces lactis Cell-Free Protein Synthesis System It's interesting to note that the yield of different proteins depends on the specific formulation of the cell-free reaction pubs.acs.org/doi/10.1021/cb…
The PNAS Collective Artificial Intelligence and Evolutionary Dynamics Special Feature showcases recent advances in research at the intersection of game theory, artificial intelligence, and population dynamics. Explore the Special Feature: ow.ly/Nl3K50WoofX
Antimicrobial peptides: structure, functions and translational applications nature.com/articles/s4157…
Dual-payload ADCs move into first oncology clinical trials nature.com/articles/d4157…
Here in @NatureSynthesis I discuss with B. J. Rasor, @AMKueffner and @erblabs developments and opportunities for biosynthesis of targeted chemicals from C1 compounds. I focused on in vitro approaches towards cell-free systems capable of self-sustaining ! nature.com/articles/s4416…
Genetically encoded control of in vitro transcription-translation coupled DNA replication biorxiv.org/content/10.110… #biorxiv_synbio
Zero-shot antibody design in a 24-well plate biorxiv.org/content/10.110… #biorxiv_synbio
Fanjun and Amogh's paper is now published: "Continuous in situ synthesis of a complete set of tRNAs sustains steady-state translation in a recombinant cell-free system" nature.com/articles/s4146…