Simone Giaveri
@simone_giaveri
@EMBOFellows Scientist @erblabs studying artificial metabolic networks. Previously PhD @SuNMIL_EPFL & @MaerklLab working on bio-inspired recycling of polymers.
Super excited to share my main research @erblabs, new in @ScienceMagazine, where I engineered a cell-free system that self-regenerates using building blocks autonomously synthesized from CO2! 🧪🫧 Let me tell you more below 👇 science.org/doi/10.1126/sc…

Really happy to share that our work on constructing six glyoxylate / glycolate sensors covering a three order of magnitude concentration range is out now in @NatureComms ! 🔥 Read below to see how we developed the sensors and what they are good for 🥳. nature.com/articles/s4146…
Review article now online: Building complex biochemicals from one-carbon compounds by Blake Rasor, @simone_giaveri, @AMKueffner & Tobias Erb @erblabs nature.com/articles/s4416… ($)
Here in @NatureSynthesis I discuss with B. J. Rasor, @AMKueffner and @erblabs developments and opportunities for biosynthesis of targeted chemicals from C1 compounds. I focused on in vitro approaches towards cell-free systems capable of self-sustaining ! nature.com/articles/s4416…
Thanks @insalutenews for highlighting my Research and my Research Interests ! 🎉 insalutenews.it/in-salute/mate…
🧠 Mutations in the #SLC13A5 gene disrupt citrate transport in neurons, causing severe #epilepsy. In a new study published in @ScienceAdvances, CeMM researchers uncover the molecular mechanisms behind this disease. ➡️ Info: bit.ly/3T4u12N 🔗Study: bit.ly/3HRy8wR
Medicine = not only about our bodies, also about world around us. Fun to talk w/ great @AlanDangour @Gautam Dey @ EMBO meeting organized by Monica Bettencourt-Dias in Lisbon. Occasion to speak about new Ri.MED research institute in Sicily youtu.be/ena0uPCRxzw
🏆 Congratulations to Prof. Francesco Stellacci @frstella from @SuNMIL_EPFL @Materials_EPFL for receiving an ERC Advanced Grant for his project Engineering Protein Interactions Using Small Molecules. Find out more: actu.epfl.ch/news/epfl-rese…
Great @EMBO workshop organised by Caterina Alfano of the Ri.MED foundation ! Join us in Palermo ! ! meetings.embo.org/event/25-struc…
New Review Out! Can we truly build life from the bottom up by encapsulating proteins we find in nature? Or should we instead also bottom-up design the proteins we utilize? 🧵1/2
New Review out! Can we eventually design not only proteins, but entire cells from scratch? Check out the review I wrote in @natrevbioeng about how to combine protein design with synthetic cell science. @SchwilleLab Link: nature.com/articles/s4422…
Paper(s) alert from our @RESOLUTE_IMI project – In a compilation of four papers in Molecular Systems Biology we show how we were deciphering cellular logistics and present a comprehensive systematic blueprint of chemical transport pathways with #SoluteCarrier transporters
Thanks for inviting me to present at the #RiMEDSymposium2025 ! Join us at rimedsymposium.eu in Palermo, such an inspiring place !

👩🔬Our new paper is out in Chem! @FeringaLab. We unveil how light-driven rotary motors behave in lipid membranes—and why system-specific characterization is crucial. Structure & polarity shape membrane interaction and function. Read (or see comments): doi.org/10.1016/j.chem…
New paper out in @ACS_AMI 🥳 We present a straightforward chemical strategy enabling efficient direct cytosolic delivery of proteins without compromising their function 🤓 #ProteinTherapeutics #CytosolicDelivery 👇Read more: pubs.acs.org/doi/10.1021/ac…
Great fun to walk throug Palermo with Donata Sandri and Nadia Consiglio to show you where the #RiMEDSymposium2025 will take place. Incredible place. Register soon rimedsymposium.eu
🌿🔬How can we fix #CO2 more efficiently in biological systems? Our new study introduces the CORE cycle, a synthetic pathway that converts CO2 to formate at aerobic conditions and ambient CO2 levels! 🚀🦠 @erblabs @mpi_marburg nature.com/articles/s4146…
Thanks @synbiocentre and @BelluatiAndrea for inviting me at the SynBio Seminar Series @TUDarmstadt ! I look forward to visiting the center! 🧬🧪 tu-darmstadt.de/synbio/worksho…

Very happy to share my @buildacell seminar ! 😎 Thank you very much @KateAdamala for hosting me ! Build-a-Cell seminar Simone Giaveri : Toward self-sustaining minimal cells The video link is below 🎥⬇️ youtu.be/v0CAdz2Ja0Q?si… via @YouTube
I am happy to share that I am one of the finalists of this year's 2025 Global Change Award (hmfoundation.com/2025/03/10/top… ). If you want to understand what we do, please watch this video: youtube.com/watch?v=mDGrBW…
💥First research paper from the lab is out in Small! 👉We show how thermally driven dynamic behaviors in #polymeric #vesicles create a versatile platform for synthetic cell applications. #SynCells #SoftMatter onlinelibrary.wiley.com/doi/10.1002/sm…
Glad to see my main PhD project finally out @NatureMicrobiol nature.com/articles/s4156… We show for the first time that a synthetic and engineered pathway can indeed exceed nature at one-carbon fixation.