Frances Arnold

@francesarnold

Innovation by evolution, Linus Pauling Professor at Caltech, Nobel Prize in Chemistry (I am an engineer of the biological world)

Caltech

Joined June 2010

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Frances Arnold@francesarnold · Mar 25

My ACS Priestley Medal address can be found here. Many stories not told in science talks... fhalab.caltech.edu/wp-content/upl…

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Frances Arnold@francesarnold · 6 h

Really proud of this work by Jae Kennemur and Yueming Long. #Enzymes rock, with a little help from #directedevolution to do #chemistry not known in nature (and not easily done by humans).

EEnzyme Chemistry@EnzymeChemistry · 7 h

#Enzymatic Stereodivergent Synthesis of Azaspiro[2.y]alkanes by Jennifer L. Kennemur, Yueming Long, Catherine J. Ko, Anuvab Das, and @francesarnold at @CaltechCCE in @J_A_C_S pubs.acs.org/doi/10.1021/ja…

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Frances Arnold@francesarnold · Jul 17

Well, I have finally made it to the top! Thanks, @Jeopardy.

PPatt "Bluechecked" Morrison@pattmlatimes · Jul 17

Hah! @francesarnold was just a clue on @Jeopardy . @Caltech @NobelPrize [Spoiler: "What are enzymes?"]

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Frances Arnold@francesarnold · Jul 12

I saw it firsthand at the #Lindau2025 Nobel Laureates meeting--international young scientists welcomed and recruited in Germany and elsewhere. Some of the very best are leaving, and many of the best will no longer come. wsj.com/politics/polic…

francesarnold's tweet card. Research-funding cuts and immigration changes threaten some of America’s economic advantages.

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Frances Arnold@francesarnold · Jun 30

My opening comments at #LINO25. Let's make sure others enjoy and understand the benefits of science. timeshighereducation.com/news/nobelist-…

francesarnold's tweet card. Frances Arnold says US science is ‘paying the price’ for not explaining benefits of research funding for ‘far too long’

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Frances Arnold Retweeted

Pernilla Wittung@PernillaWittung · Jun 29

#LINO25 officially opened!! So happy to have so many young scientists and Nobel laureates here in beautiful Lindau for a week of chemistry!

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Frances Arnold@francesarnold · Jun 29

I'm thrilled to be @lindaunobel In beautiful #Lindau with 606 young scientists, and quite a few older ones, too.

PProf. Anima Anandkumar@AnimaAnandkumar · Jun 29

Great opening at Lindau Nobel laureate event by @francesarnold I will be speaking on the panel of AI in chemistry later in the week #LINO25

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Frances Arnold Retweeted

Sam Rodriques@SGRodriques · May 13

Chenghao Liu will work with FutureHouse and Nobel laureate Frances Arnold @francesarnold at Caltech to develop closed-loop generative machine learning workflows for de novo enzyme discovery. Chenghao was co-founder of Dreamfold and known for combining physical organic chemistry…

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Frances Arnold@francesarnold · Jun 27

Really enjoying #Repartzymes Repurposed and Artificial Enzymes meeting organized by #TomWard of Uni. Basel. Many former group members are here! rep.artzymes.info

francesarnold's tweet image. Really enjoying #Repartzymes Repurposed and Artificial Enzymes meeting organized by #TomWard of Uni. Basel. Many former group members are here! rep.artzymes.info

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Frances Arnold@francesarnold · May 23

I absolutely love this paper!! 🌟 Beautiful work by @jsunn_y @yisongyue and team to show that discrete diffusion models can be effectively guided by fitness data from low-throughput wet-lab assays! 🧪 I'm telling you guys: guided sequence generation is where it's at! 🤙

JJason Yang@jsunn_y · May 22

I'm excited to share our new preprint "Steering Generative Models with Experimental Data for Protein Fitness Optimization" (🧵1/5)! Paper: arxiv.org/abs/2505.15093 Code: github.com/jsunn-y/SGPO

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Frances Arnold Retweeted

Jason Yang@jsunn_y · May 22

I'm excited to share our new preprint "Steering Generative Models with Experimental Data for Protein Fitness Optimization" (🧵1/5)! Paper: arxiv.org/abs/2505.15093 Code: github.com/jsunn-y/SGPO

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FutureHouse@FutureHouseSF · May 13

Chenghao Liu will work with FutureHouse and Nobel laureate @francesarnold at Caltech to develop closed-loop generative machine learning workflows for de novo enzyme discovery. Chenghao was co-founder of Dreamfold and known for combining physical organic chemistry with generative…

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Frances Arnold@francesarnold · Mar 29

Fun at #ACSSpring2025 awards banquet with @Lu_Wei8 @CaltechCCE and Rick Kaner.

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Frances Arnold@francesarnold · Mar 27

Celebrating Jeff Moore @Merck award at the #ACSSpring2025 awards dinner! Way to go, Jeff. #enzymes #biocatalysis #directedevolutioh.

francesarnold's tweet image. Celebrating Jeff Moore @Merck award at the #ACSSpring2025 awards dinner! Way to go, Jeff. #enzymes #biocatalysis #directedevolutioh.

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Frances Arnold@francesarnold · Mar 27

Highlight of #ACSSpring2025 was gathering with current and former Arnold group members.

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C&EN (Chemical & Engineering News)@cenmag · Mar 13

Meet @francesarnold, 2025 Priestley Medalist, at #ACSSpring2025. Stop by the ACS Booth Theater in the Expo Hall to hear about her contributions to #chemistry and pick up a signed copy of her C&EN feature issue. RSVP: connect.discoveracs.org/cen-priestley-…

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TIME@TIME · Feb 6

Anima Anandkumar uses AI to make key discoveries, from advanced weather forecasting to novel medical devices time.com/7212504/time10…

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Frances Arnold@francesarnold · Jan 20

The White House web site with all the Biden PCAST products has been wiped clean. But, thanks to @erichorvitz, you can still find all our reports at erichorvitz.com/PCAST_reports_….

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Max Planck Institute for Terrestrial Microbiology@mpi_marburg · Jan 20

Exciting Opportunity! 📣 The Max Planck Institute for Terrestrial Microbiology is hiring a Head of the DNA Biofoundry. Join us in vibrant #Marburg to develop cutting-edge automation platforms that empower synthetic biology research. 🗓️ Apply by Feb 15, 2025. #ScienceJobs #SynBio

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